Histopathological and prognostic significance of the expression of sex hormone receptors in bladder cancer: A meta-analysis of immunohistochemical studies

• Published in: PloS one Vol. 12; no. 3; p. e0174746
• Main Authors: Ide, Hiroki, Inoue, Satoshi, Miyamoto, Hiroshi
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 31.03.2017; Public Library of Science (PLoS)
• Subjects: Activation; Activin; Analysis; Androgen receptors; Androgens; Antibodies; Arches; Bibliographies; Biology and Life Sciences; Biotechnology; Bladder; Bladder cancer; Breast; Breast carcinoma; Cancer; Carcinogenesis; Carcinogens; Cell lines; Cell proliferation; Chemotherapy; Classification; Data processing; Development and progression; DNA microarrays; Documents; Estrogen Receptor alpha - metabolism; Estrogen Receptor beta - metabolism; Estrogen receptors; Estrogens; Female; Flow cytometry; Formaldehyde; Gene expression; Geographical distribution; Health risk assessment; Health risks; Histopathology; Hormone receptors; Hormones; Humans; Immunohistochemistry; Immunohistochemistry - methods; Male; Markers; Medical prognosis; Medicine; Medicine and Health Sciences; Meta-analysis; Metastases; Multivariate analysis; Neoplasms; Pathology; Pharmacology; Physical Sciences; Physiological aspects; Prognosis; Quality; Quality control; Quantitative analysis; Radiation therapy; Receptors, Androgen - metabolism; Research and Analysis Methods; Retrospective Studies; Risk; Sex; Software; Studies; Survival; Tumors; Urinary bladder; Urinary Bladder Neoplasms - metabolism; Urinary Bladder Neoplasms - pathology; Urinary tract; Urology; United States; New York; United States > US; Maryland; Baltimore Maryland

Emerging preclinical evidence suggests the involvement of sex hormones and their receptor signals in the development and progression of bladder cancer. Meanwhile, previous studies have demonstrated conflicting results on the relationship between the status of sex hormone receptors in urothelial tumo...