Fluid Flow along Venous Adventitia in Rabbits: Is It a Potential Drainage System Complementary to Vascular Circulations?

• Published in: PloS one Vol. 7; no. 7; p. e41395
• Main Authors: Li, Hong-yi, Chen, Min, Yang, Jie-fu, Yang, Chong-qing, Xu, Liang, Wang, Fang, Tong, Jia-bin, Lv, You, Suonan, Caidan
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 26.07.2012; Public Library of Science (PLoS)
• Subjects: Acupuncture; Adventitia - diagnostic imaging; Adventitia - physiology; Adventitia - ultrastructure; Animal experimentation; Animal research; Animals; Biology; Blood Circulation - physiology; Blood vessels; Cardiology; Collagen; Collagen (type I); Collagenase; Comparative analysis; Connective tissues; Effusion; Electric properties; Electron microscopy; Experiments; Extracellular matrix; Fluid dynamics; Fluid flow; Fluorescein; Fluorescein - pharmacology; Histology; Hospitals; Humans; Hydraulic conductivity; Hydrogeology; Intestine; Limbs; Low molecular weights; Lymphangiography; Lymphatic system; Lymphatic Vessels - diagnostic imaging; Lymphatic Vessels - physiology; Lymphatic Vessels - ultrastructure; Magnetic resonance; Magnetic Resonance Angiography; Magnetic resonance imaging; Medicine; Molecular weight; Permeability coefficient; Photography; Rabbits; Radioactive Tracers; Radiography; Rodents; Skin; Sodium; Studies; Tissues; Tracers; Tracers (Biology); Veins - physiology; Veins - ultrastructure; Beijing China; China

Our previous research and other studies with radiotracers showed evidence of a centripetal drainage pathway, separate from blood or lymphatic vessels, that can be visualized when a small amount of low molecular weight tracer is injected subcutaneously into a given region on skin of humans. In order...