Correlation study of FGF23/D-serine in maintenance hemodialysis patients with combined hearing impairment

• Published in: PloS one Vol. 18; no. 1; p. e0280378
• Main Authors: Yuan, Dunlu, Li, Jiaqing, Guo, Min, Yang, Qing, Huang, Jingjing, Nie, Jingwen, Li, Ruomei, Li, Qing
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 17.01.2023; Public Library of Science (PLoS)
• Subjects: Age; Audiometry; Biology and Life Sciences; Biomarkers; Blood; Care and treatment; Case-Control Studies; Chromatography; Chronic kidney failure; Complications and side effects; Consent; Correlation; Correlation analysis; Correlation of Data; Creatinine; D-Serine; Data collection; Diagnosis; Drug use; Ear diseases; End-stage renal disease; Enzyme-linked immunosorbent assay; Enzymes; Failure; Family medical history; Fibroblast growth factor 23; Fibroblast Growth Factors; Growth factors; Health aspects; Health risks; Hearing; Hearing disorders; Hearing loss; Hemodialysis; Hemodialysis patients; High performance liquid chromatography; Humans; Impairment; Kidney diseases; Kidney Failure, Chronic - complications; Kidney Failure, Chronic - therapy; Laboratories; Liquid chromatography; Maintenance; Measurement; Medicine and Health Sciences; Metabolism; Phosphorus; Physiology; Potassium; Questionnaires; Regression analysis; Renal Dialysis; Renal failure; Renal Insufficiency, Chronic - complications; Risk analysis; Risk factors; Serine; Statistical analysis; Variables; China; Denmark

Recent studies have reported an association between chronic renal failure and hearing impairment. Yet, the exact mechanism of action is still not fully understood. In this study, we investigated the expression of fibroblast growth factor 23 (FGF23) and D-serine in maintenance hemodialysis (MHD) pati...