Therapeutic Role of Ursolic Acid on Ameliorating Hepatic Steatosis and Improving Metabolic Disorders in High-Fat Diet-Induced Non-Alcoholic Fatty Liver Disease Rats - Li, Songtao; Meng, Fanyu; Liao, Xilu; Wang, Yemei; Sun, Zongxiang; Guo, Fuchuan; Li, Xiaoxia; Meng, Man; Li, Ying; Sun, Changhao (PloS one, 2014)
Keywords: Acid resistance; Acids; Animals; Biology; CD36 Antigens - genetics; CD36 Antigens - metabolism; Diabetes mellitus; Diacylglycerol O-Acyltransferase - genetics; Diacylglycerol O-Acyltransferase - metabolism; Diet; Diet, High-Fat; Dietary Fats - adverse effects; Disorders; Enzymes; Fatty liver; Fatty Liver - drug therapy; Fatty Liver - etiology; Fatty Liver - metabolism; Fatty Liver - pathology; Gene Expression; Health aspects; High fat diet; Insulin; Insulin Resistance; Laboratory animals; Lipase - genetics; Lipase - metabolism; Lipid metabolism; Lipid Metabolism - drug effects; Lipids; Liver; Liver - drug effects; Liver - metabolism; Liver - pathology; Liver diseases; Male; Medicine; Metabolic disorders; Metabolism; mRNA; Non-alcoholic Fatty Liver Disease; Obesity; Obesity - drug therapy; Obesity - etiology; Obesity - metabolism; Obesity - pathology; Oxidation resistance; Oxidative stress; Peroxisome proliferator-activated receptors; Plants (botany); PPAR alpha - antagonists & inhibitors; PPAR alpha - genetics; PPAR alpha - metabolism; Rats; Rats, Sprague-Dawley; RNA; RNA, Messenger - genetics; RNA, Messenger - metabolism; RNA, Small Interfering - genetics; RNA, Small Interfering - metabolism; Rodents; Steatosis; Triterpenes - pharmacology; Ursolic Acid