Effect on physiological parameters and anaesthetic dose requirement of isoflurane when tramadol given as a continuous rate infusion vs a single intravenous bolus injection during ovariohysterectomy in dogs

• Published in: PloS one Vol. 18; no. 2; p. e0281602
• Main Authors: Costa, Giovanna L., Di Pietro, Simona, Interlandi, Claudia, Leonardi, Fabio, Macrì, Daniele, Ferrantelli, Vincenzo, Macrì, Francesco
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 08.02.2023; Public Library of Science (PLoS)
• Subjects: Abnormalities; Acepromazine; Alveoli; Anesthesia; Anesthetics; Animals; Biology and Life Sciences; Blood pressure; Body temperature; Complications and side effects; Dogs; Drug delivery systems; Female; Health aspects; Heart beat; Heart rate; Humans; Injection; Intravenous administration; Intubation; Isoflurane; Laboratories; Medicine and Health Sciences; Narcotics; Normal distribution; Ovaries; Oxygen; Parameters; Patient outcomes; Physiological aspects; Physiological effects; Physiology; Reduction; Respiration; Respiratory rate; Sevoflurane; Skin; Statistical analysis; Sutures; Tachycardia; Tiletamine - pharmacology; Tramadol; Twitching; Zolazepam - pharmacology; Italy; United States > US

Tramadol produces a significant reduction in both sevoflurane and isoflurane minimum alveolar concentrations in dogs under experimental conditions. This study aims to compare the effects of tramadol administered as a constant rate infusion (CRI) with those of tramadol administered as a single intrav...