Grape Seed Proanthocyanidin Extract Ameliorates Diabetic Bladder Dysfunction via the Activation of the Nrf2 Pathway - Chen, Shouzhen; Zhu, Yaofeng; Liu, Zhifeng; Gao, Zhaoyun; Li, Baoying; Zhang, Dongqing; Zhang, Zhaocun; Jiang, Xuewen; Liu, Zhengfang; Meng, Lingquan; Yang, Yue; Shi, Benkang (PloS one, 2015)
Keywords: Analysis; Animals; Antioxidants; Antioxidants (Nutrients); Apoptosis; Apoptosis - drug effects; BAX protein; Bcl-2 protein; Bladder; Care and treatment; Caspase; Caspase-3; Chromatography; Complications and side effects; Diabetes; Diabetes Complications - drug therapy; Diabetes Complications - pathology; Diabetes Complications - physiopathology; Diabetes mellitus; Diabetes Mellitus, Experimental - complications; DNA nucleotidylexotransferase; Female; Grape Seed Extract - therapeutic use; Growth factors; Health aspects; Hyperglycemia; Metabolism; Nerve growth factor; Neuroprotection; NF-E2-Related Factor 2 - metabolism; Oxidative stress; Oxidative Stress - drug effects; Pharmacology; Plant extracts; Proanthocyanidins; Proanthocyanidins - therapeutic use; Proteins; Rats; Rats, Wistar; Rodents; Signal Transduction - drug effects; Smooth muscle; Streptozocin; Studies; Urinary bladder; Urinary Bladder - drug effects; Urinary Bladder - pathology; Urinary Bladder - physiopathology; Urology; China