Multi-omics subtyping pipeline for chronic obstructive pulmonary disease - Gillenwater, Lucas A.; Helmi, Shahab; Stene, Evan; Pratte, Katherine A.; Zhuang, Yonghua; Schuyler, Ronald P.; Lange, Leslie; Castaldi, Peter J.; Hersh, Craig P.; Banaei-Kashani, Farnoush; Bowler, Russell P.; Kechris, Katerina J. (PloS one, 2021)
Keywords: Age Factors; Aged; Biology and Life Sciences; Blood tests; Carbon monoxide; Care and treatment; Chronic obstructive pulmonary disease; Clinical medicine; Cluster Analysis; Clustering; College campuses; Computer science; Databases, Factual; Datasets; Diagnosis; Engineering schools; Female; Fibrillation; Gene expression; Gene Expression Profiling - methods; Gene Expression Regulation; Gene Regulatory Networks; Health risk assessment; Heterogeneity; Humans; Immune response; Informatics; Lung diseases; Lung diseases, Obstructive; Male; Medicine; Medicine and Health Sciences; Metabolites; Metabolomics; Metabolomics - methods; Methods; Middle Aged; Molecular biology; Obstructive lung disease; Phenotype; Phenotypes; Proteins; Proteomes; Proteomics; Proteomics - methods; Public health; Pulmonary Disease, Chronic Obstructive - blood; Pulmonary Disease, Chronic Obstructive - classification; Pulmonary Disease, Chronic Obstructive - genetics; Research and Analysis Methods; Risk factors; Sample size; Sphingomyelin; Support Vector Machine; Support vector machines; Transcriptomes; United States; United States--US; Colorado