Serum Concentrations of Fibroblast Growth Factors 19 and 21 in Women with Gestational Diabetes Mellitus: Association with Insulin Resistance, Adiponectin, and Polycystic Ovary Syndrome History

• Published in: PloS one Vol. 8; no. 11; p. e81190
• Main Authors: Wang, Dongyu, Zhu, Wenjing, Li, Jieming, An, Chongyou, Wang, Zilian
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 19.11.2013; Public Library of Science (PLoS)
• Subjects: Adiponectin; Adiponectin - blood; Adiponectin - genetics; Adult; Analysis; Anthropometry; Case-Control Studies; Correlation; Dextrose; Diabetes Complications - blood; Diabetes Complications - etiology; Diabetes Complications - physiopathology; Diabetes in pregnancy; Diabetes mellitus; Diabetes, Gestational - blood; Diabetes, Gestational - physiopathology; Enzyme-linked immunosorbent assay; Enzymes; Female; Fibroblast growth factors; Fibroblast Growth Factors - blood; Fibroblast Growth Factors - genetics; Gene Expression; Gestational Age; Gestational diabetes; Glucose; Glucose tolerance; Growth factors; Homeostasis; Humans; Insulin; Insulin - blood; Insulin - genetics; Insulin Resistance; Kinases; Medical research; Medicine, Experimental; Patients; Polycystic ovary syndrome; Polycystic Ovary Syndrome - blood; Polycystic Ovary Syndrome - complications; Polycystic Ovary Syndrome - physiopathology; Pregnancy; Pregnant women; Rodents; Serum levels; Stein-Leventhal syndrome; Triglycerides; Triglycerides - blood; Type 2 diabetes; Womens health; China

Fibroblast growth factor 19 (FGF19) and FGF21 are considered to be novel adipokines that improve glucose tolerance and insulin sensitivity. In the current study, we investigated serum FGF19 and FGF21 levels in patients with gestational diabetes mellitus (GDM) and explored their relationships with an...