Metformin doses to ensure efficacy and safety in patients with reduced kidney function - Kuan, Isabelle H. S.; Wilson, Luke C.; Leishman, Jed C.; Cosgrove, Samuel; Walker, Robert J.; Putt, Tracey L.; Schollum, John B. W.; Wright, Daniel F. B. (PloS one, 2021)
Keywords: Acidosis; Adult; Aged; Antidiabetics; Bioavailability; Biology and Life Sciences; Collaboration; Creatinine; Diabetes; Diabetes Mellitus, Type 2 - complications; Diabetes Mellitus, Type 2 - drug therapy; Dosage; Dosage and administration; Drug Dosage Calculations; Drug dosages; Drug therapy; Epidemiology; Epidermal growth factor receptors; Evaluation; Female; Humans; Hypoglycemic Agents - administration & dosage; Hypoglycemic Agents - adverse effects; Hypoglycemic Agents - pharmacokinetics; Hypoglycemic Agents - therapeutic use; Kidney diseases; Kidney Diseases - complications; Kidney Function Tests; Kidneys; Lower bounds; Male; Medicine; Medicine and Health Sciences; Metformin; Metformin - administration & dosage; Metformin - adverse effects; Metformin - pharmacokinetics; Metformin - therapeutic use; Middle Aged; Patients; Pharmacokinetics; Pharmacy; Plasma; Practice guidelines (Medicine); Quantitative analysis; Research and Analysis Methods; Simulation; Young Adult; Europe; New Zealand