Circulating CTRP9 correlates with the prevention of aortic calcification in renal allograft recipients

• Published in: PloS one Vol. 15; no. 1; p. e0226526
• Main Authors: Miyatake, Nobuhiko, Adachi, Hiroki, Nomura-Nakayama, Kanae, Okada, Keiichiro, Okino, Kazuaki, Hayashi, Norifumi, Fujimoto, Keiji, Furuichi, Kengo, Yokoyama, Hitoshi
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 16.01.2020; Public Library of Science (PLoS)
• Subjects: Adiponectin; Adiponectin - blood; Adult; Aging; Analysis; Aorta; Aorta - pathology; Arteries; Arteriosclerosis; Atherosclerosis; Berries; Biology and Life Sciences; Calcification; Calcification (ectopic); Calcification (Physiology); Cardiovascular disease; Cardiovascular diseases; CAT scans; Cholesterol; Computed tomography; Coronary vessels; Correlation; Death; Diabetes; Drug use; Enzymes; Epidermal growth factor receptors; Female; Fluorescent antibody technique; Glomerular Filtration Rate; Heart diseases; Humans; Immunofluorescence; Immunoglobulins; Insulin; Kidney transplantation; Kidney Transplantation - methods; Kidneys; Kinases; Lipids; Male; Medical prognosis; Medicine; Medicine and Health Sciences; Molecular weight; Multiple regression analysis; Nephrology; Organ transplant recipients; Organ transplantation; Physical Sciences; Prevention; Proteins; Receptors; Regression analysis; Research and Analysis Methods; Statistical analysis; Surgery; Transplantation; Transplantation, Homologous; Transplants & implants; Tumor Necrosis Factor Receptor-Associated Peptides and Proteins - blood; Tumor necrosis factor-α; Vascular Calcification - blood; Vascular Calcification - prevention & control; Young Adult; Japan

Cardiovascular disease (CVD) due to atherosclerosis is a major cause of death in renal allograft recipients. Recently, C1q/TNF-α related protein-9 (CTRP9), which is a paralog of adiponectin (ADPN), has been suggested to be related to the prevention of atherosclerosis and the occurrence of CVD, but t...