Phospholipase D2 is involved in the formation of Golgi tubules and ArfGAP1 recruitment
Lipids and lipid-modifying enzymes play a key role in the biogenesis, maintenance and fission of transport carriers in the secretory and endocytic pathways. In the present study we demonstrate that phosphatidic acid generated by phospholipase D2 (PLD2) is involved in the formation of Golgi tubules....
Saved in:
Published in | PloS one Vol. 9; no. 10; p. e111685 |
---|---|
Main Authors | , , , |
Format | Journal Article |
Language | English |
Published |
United States
Public Library of Science
29.10.2014
Public Library of Science (PLoS) |
Subjects | |
Online Access | Get full text |
Cover
Loading…
Abstract | Lipids and lipid-modifying enzymes play a key role in the biogenesis, maintenance and fission of transport carriers in the secretory and endocytic pathways. In the present study we demonstrate that phosphatidic acid generated by phospholipase D2 (PLD2) is involved in the formation of Golgi tubules. The main evidence to support this is: 1) inhibitors of phosphatidic acid formation and PLD2 depletion inhibit the formation of tubules containing resident enzymes and regulators of intra-Golgi transport in a low temperature (15°C) model of Golgi tubulation but do not affect brefeldin A-induced tubules, 2) inhibition of PLD2 enzymatic activity and PLD2 depletion in cells cultured under physiological conditions (37°C) induce the formation of tubules specifically containing Golgi matrix proteins, and, 3) over-expression of PLD2 induces the formation of a tubular network. In addition, it was found that the generation of this lipid by the isoenzyme is necessary for ArfGAP1 recruitment to Golgi membranes. These results suggest that both proteins are involved in the molecular mechanisms which drive the formation of different types of Golgi tubules. |
---|---|
AbstractList | Lipids and lipid-modifying enzymes play a key role in the biogenesis, maintenance and fission of transport carriers in the secretory and endocytic pathways. In the present study we demonstrate that phosphatidic acid generated by phospholipase D2 (PLD2) is involved in the formation of Golgi tubules. The main evidence to support this is: 1) inhibitors of phosphatidic acid formation and PLD2 depletion inhibit the formation of tubules containing resident enzymes and regulators of intra-Golgi transport in a low temperature (15°C) model of Golgi tubulation but do not affect brefeldin A-induced tubules, 2) inhibition of PLD2 enzymatic activity and PLD2 depletion in cells cultured under physiological conditions (37°C) induce the formation of tubules specifically containing Golgi matrix proteins, and, 3) over-expression of PLD2 induces the formation of a tubular network. In addition, it was found that the generation of this lipid by the isoenzyme is necessary for ArfGAP1 recruitment to Golgi membranes. These results suggest that both proteins are involved in the molecular mechanisms which drive the formation of different types of Golgi tubules. |
Audience | Academic |
Author | Ballesta, José Martínez-Martínez, Narcisa Martínez-Alonso, Emma Martínez-Menárguez, José A |
AuthorAffiliation | National Cancer Institute, United States of America Department of Cell Biology and Histology, Medical School, IMIB-Arrixaca, University of Murcia, Murcia, Spain |
AuthorAffiliation_xml | – name: Department of Cell Biology and Histology, Medical School, IMIB-Arrixaca, University of Murcia, Murcia, Spain – name: National Cancer Institute, United States of America |
Author_xml | – sequence: 1 givenname: Narcisa surname: Martínez-Martínez fullname: Martínez-Martínez, Narcisa organization: Department of Cell Biology and Histology, Medical School, IMIB-Arrixaca, University of Murcia, Murcia, Spain – sequence: 2 givenname: Emma surname: Martínez-Alonso fullname: Martínez-Alonso, Emma organization: Department of Cell Biology and Histology, Medical School, IMIB-Arrixaca, University of Murcia, Murcia, Spain – sequence: 3 givenname: José surname: Ballesta fullname: Ballesta, José organization: Department of Cell Biology and Histology, Medical School, IMIB-Arrixaca, University of Murcia, Murcia, Spain – sequence: 4 givenname: José A surname: Martínez-Menárguez fullname: Martínez-Menárguez, José A organization: Department of Cell Biology and Histology, Medical School, IMIB-Arrixaca, University of Murcia, Murcia, Spain |
BackLink | https://www.ncbi.nlm.nih.gov/pubmed/25354038$$D View this record in MEDLINE/PubMed |
BookMark | eNqNkl2L1DAUhousuB_6D0QLgujFjPlokvZGGFYdBxZ20WVvQ5om0wxpMybpoP_ezE53mcpeSC4STp7znpyT9zw76V2vsuw1BHOIGfy0cYPvhZ1vU3gOIIS0JM-yM1hhNKMI4JOj82l2HsIGAIJLSl9kp4hgUgBcnmV3N60L29ZZsxVB5V9QbkJu-p2zO9WkQx5blWvnOxGN63On86Wza5PHoR6sCrnom3zh9XJxA3OvpB9M7FQfX2bPtbBBvRr3i-z229fby--zq-vl6nJxNZO0QnHGBGJYQkkp0xpIzAgVNdSEQYwIQRQQWikpBKzqSuuKNVQqUhdVoQiTVOCL7O1Bdmtd4ONEAocUlpCgAhaJWB2IxokN33rTCf-HO2H4fcD5NRc-GmkVr2pFoZCsLGtcpPcJLGtRsIZUFcOqYEnr81htqDvVyNSnF3YiOr3pTcvXbscLBDGgMAl8GAW8-zWoEHlnglTWil654f7dFYa4BGVC3_2DPt3dSK1FasD02qW6ci_KFwVkGGEMUKLmT1BpNaozMtlHmxSfJHycJCQmqt9xLYYQ-Ornj_9nr--m7PsjtlXCxjY4O-ytFaZgcQCldyF4pR-HDAHfu_9hGnzvfj66P6W9Of6gx6QHu-O_MMf_Uw |
CitedBy_id | crossref_primary_10_1038_s41416_019_0610_7 crossref_primary_10_1002_1873_3468_13563 crossref_primary_10_1088_1748_6041_10_5_055014 crossref_primary_10_1038_ncomms12148 crossref_primary_10_1371_journal_pone_0160838 crossref_primary_10_1371_journal_pone_0135260 |
Cites_doi | 10.1073/pnas.0611360104 10.1034/j.1600-0854.2003.00078.x 10.1016/j.bmcl.2009.02.057 10.1007/s00418-013-1114-9 10.1074/jbc.M110.183772 10.1016/j.cellbi.2006.09.020 10.7554/eLife.02009 10.1155/2013/126731 10.1038/nature02108 10.1016/j.tcb.2006.08.008 10.1034/j.1600-0854.2000.010608.x 10.1091/mbc.E07-04-0334 10.1091/mbc.E02-11-0730 10.1016/j.bbalip.2012.04.004 10.1242/jcs.117705 10.1134/S0006297912010014 10.1016/0092-8674(90)90096-W 10.1083/jcb.200108017 10.1038/nrm1784 10.1016/j.febslet.2009.10.031 10.1038/ncb2273 10.1074/jbc.272.49.30848 10.1016/S0021-9258(17)36324-X 10.1016/S0960-9822(06)00153-9 10.1016/j.ceb.2007.06.003 10.1091/mbc.E08-03-0256 10.1016/j.plipres.2006.01.005 10.1091/mbc.12.4.943 10.1242/jcs.111.22.3411 10.1016/j.bbalip.2009.04.001 10.1074/jbc.M202969200 10.1038/ncb1180 10.1091/mbc.E03-05-0295 10.1111/j.1600-0854.2004.00242.x 10.1016/j.ceb.2010.05.002 10.1111/j.1600-0854.2006.00533.x 10.1021/cr200296t 10.1016/S0960-9822(97)70090-3 10.1021/jm100814g 10.1016/j.plipres.2011.12.003 10.1021/bi0478502 10.1042/bj3600707 10.1101/cshperspect.a005181 10.1091/mbc.02-04-0059 10.1016/0003-9861(87)90199-8 10.1016/j.bbamem.2011.05.006 10.1091/mbc.E02-11-0711 10.1016/S0092-8674(03)01079-1 10.1111/j.1748-1716.2011.02298.x 10.1038/ncb1774 10.1016/j.semcdb.2010.07.002 10.1074/jbc.M804528200 10.1111/j.1600-0854.2008.00711.x |
ContentType | Journal Article |
Copyright | COPYRIGHT 2014 Public Library of Science 2014 Martínez-Martínez et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. 2014 Martínez-Martínez et al 2014 Martínez-Martínez et al |
Copyright_xml | – notice: COPYRIGHT 2014 Public Library of Science – notice: 2014 Martínez-Martínez et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. – notice: 2014 Martínez-Martínez et al 2014 Martínez-Martínez et al |
DBID | CGR CUY CVF ECM EIF NPM AAYXX CITATION IOV ISR 3V. 7QG 7QL 7QO 7RV 7SN 7SS 7T5 7TG 7TM 7U9 7X2 7X7 7XB 88E 8AO 8C1 8FD 8FE 8FG 8FH 8FI 8FJ 8FK ABJCF ABUWG AFKRA ARAPS ATCPS AZQEC BBNVY BENPR BGLVJ BHPHI C1K CCPQU D1I DWQXO FR3 FYUFA GHDGH GNUQQ H94 HCIFZ K9. KB. KB0 KL. L6V LK8 M0K M0S M1P M7N M7P M7S NAPCQ P5Z P62 P64 PATMY PDBOC PIMPY PQEST PQQKQ PQUKI PTHSS PYCSY RC3 7X8 5PM DOA |
DOI | 10.1371/journal.pone.0111685 |
DatabaseName | Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed CrossRef Gale In Context: Opposing Viewpoints Gale In Context: Science ProQuest Central (Corporate) Animal Behavior Abstracts Bacteriology Abstracts (Microbiology B) Biotechnology Research Abstracts Nursing & Allied Health Database Ecology Abstracts Entomology Abstracts (Full archive) Immunology Abstracts Meteorological & Geoastrophysical Abstracts Nucleic Acids Abstracts Virology and AIDS Abstracts Agricultural Science Collection Health & Medical Collection ProQuest Central (purchase pre-March 2016) Medical Database (Alumni Edition) ProQuest Pharma Collection Public Health Database Technology Research Database ProQuest SciTech Collection ProQuest Technology Collection ProQuest Natural Science Collection Hospital Premium Collection Hospital Premium Collection (Alumni Edition) ProQuest Central (Alumni) (purchase pre-March 2016) Materials Science & Engineering Collection ProQuest Central (Alumni) ProQuest Central Advanced Technologies & Aerospace Collection Agricultural & Environmental Science Collection ProQuest Central Essentials Biological Science Collection ProQuest Central Technology Collection Natural Science Collection Environmental Sciences and Pollution Management ProQuest One Community College ProQuest Materials Science Collection ProQuest Central Korea Engineering Research Database Health Research Premium Collection Health Research Premium Collection (Alumni) ProQuest Central Student AIDS and Cancer Research Abstracts SciTech Premium Collection ProQuest Health & Medical Complete (Alumni) Materials Science Database Nursing & Allied Health Database (Alumni Edition) Meteorological & Geoastrophysical Abstracts - Academic ProQuest Engineering Collection Biological Sciences Agriculture Science Database Health & Medical Collection (Alumni Edition) Medical Database Algology Mycology and Protozoology Abstracts (Microbiology C) Biological Science Database Engineering Database Nursing & Allied Health Premium Advanced Technologies & Aerospace Database ProQuest Advanced Technologies & Aerospace Collection Biotechnology and BioEngineering Abstracts Environmental Science Database Materials Science Collection Publicly Available Content Database ProQuest One Academic Eastern Edition (DO NOT USE) ProQuest One Academic ProQuest One Academic UKI Edition Engineering Collection Environmental Science Collection Genetics Abstracts MEDLINE - Academic PubMed Central (Full Participant titles) DOAJ Directory of Open Access Journals |
DatabaseTitle | MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) CrossRef Agricultural Science Database Publicly Available Content Database ProQuest Central Student ProQuest Advanced Technologies & Aerospace Collection ProQuest Central Essentials Nucleic Acids Abstracts SciTech Premium Collection Environmental Sciences and Pollution Management Health Research Premium Collection Meteorological & Geoastrophysical Abstracts Natural Science Collection Biological Science Collection ProQuest Medical Library (Alumni) Engineering Collection Advanced Technologies & Aerospace Collection Engineering Database Virology and AIDS Abstracts ProQuest Biological Science Collection ProQuest One Academic Eastern Edition Agricultural Science Collection ProQuest Hospital Collection ProQuest Technology Collection Health Research Premium Collection (Alumni) Biological Science Database Ecology Abstracts ProQuest Hospital Collection (Alumni) Biotechnology and BioEngineering Abstracts Environmental Science Collection Entomology Abstracts Nursing & Allied Health Premium ProQuest Health & Medical Complete ProQuest One Academic UKI Edition Environmental Science Database ProQuest Nursing & Allied Health Source (Alumni) Engineering Research Database ProQuest One Academic Meteorological & Geoastrophysical Abstracts - Academic Technology Collection Technology Research Database Materials Science Collection ProQuest Health & Medical Complete (Alumni) ProQuest Central (Alumni Edition) ProQuest One Community College ProQuest Natural Science Collection ProQuest Pharma Collection ProQuest Central Genetics Abstracts ProQuest Engineering Collection Biotechnology Research Abstracts Health and Medicine Complete (Alumni Edition) ProQuest Central Korea Bacteriology Abstracts (Microbiology B) Algology Mycology and Protozoology Abstracts (Microbiology C) Agricultural & Environmental Science Collection AIDS and Cancer Research Abstracts Materials Science Database ProQuest Materials Science Collection ProQuest Public Health ProQuest Nursing & Allied Health Source ProQuest SciTech Collection Advanced Technologies & Aerospace Database ProQuest Medical Library Animal Behavior Abstracts Materials Science & Engineering Collection Immunology Abstracts ProQuest Central (Alumni) MEDLINE - Academic |
DatabaseTitleList | Agricultural Science Database MEDLINE |
Database_xml | – sequence: 1 dbid: DOA name: Directory of Open Access Journals url: https://www.doaj.org/ sourceTypes: Open Website – sequence: 2 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 3 dbid: EIF name: MEDLINE url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search sourceTypes: Index Database – sequence: 4 dbid: 8FG name: ProQuest Technology Collection url: https://search.proquest.com/technologycollection1 sourceTypes: Aggregation Database |
DeliveryMethod | fulltext_linktorsrc |
Discipline | Sciences (General) Biology |
DocumentTitleAlternate | Phospholipase D2 and Golgi Tubules |
EISSN | 1932-6203 |
Editor | Randazzo, Paul A. |
Editor_xml | – sequence: 1 givenname: Paul A. surname: Randazzo fullname: Randazzo, Paul A. |
EndPage | e111685 |
ExternalDocumentID | 1618152414 oai_doaj_org_article_9be61ac788b34c69a3cba47d59973e47 3475417321 A417323302 10_1371_journal_pone_0111685 25354038 |
Genre | Research Support, Non-U.S. Gov't Journal Article |
GeographicLocations | Spain |
GeographicLocations_xml | – name: Spain |
GroupedDBID | --- 123 29O 2WC 3V. 53G 5VS 7RV 7X2 7X7 7XC 88E 8AO 8C1 8CJ 8FE 8FG 8FH 8FI 8FJ A8Z AAFWJ ABDBF ABIVO ABJCF ABUWG ACGFO ACIHN ACIWK ACPRK ADBBV ADRAZ AEAQA AENEX AFKRA AFRAH AHMBA ALIPV ALMA_UNASSIGNED_HOLDINGS AOIJS APEBS ARAPS ATCPS BAWUL BBNVY BBORY BCNDV BENPR BGLVJ BHPHI BKEYQ BPHCQ BVXVI BWKFM CCPQU CGR CS3 CUY CVF D1I D1J D1K DIK DU5 E3Z EAP EAS EBD ECM EIF EMOBN ESTFP ESX EX3 F5P FPL FYUFA GROUPED_DOAJ GX1 HCIFZ HH5 HMCUK HYE IAO IEA IHR IHW INH INR IOV IPNFZ IPY ISE ISR ITC K6- KB. KQ8 L6V LK5 LK8 M0K M1P M48 M7P M7R M7S M~E NAPCQ NPM O5R O5S OK1 P2P P62 PATMY PDBOC PIMPY PQQKQ PROAC PSQYO PTHSS PV9 PYCSY RIG RNS RPM RZL SV3 TR2 UKHRP WOQ WOW ~02 ~KM AAYXX CITATION AFPKN 7QG 7QL 7QO 7SN 7SS 7T5 7TG 7TM 7U9 7XB 8FD 8FK AZQEC C1K DWQXO FR3 GNUQQ H94 K9. KL. M7N P64 PQEST PQUKI RC3 7X8 5PM - 02 AAPBV ABPTK ADACO BBAFP KM |
ID | FETCH-LOGICAL-c692t-7a273c1c667ff0c3756ab1f5713255260569ecaa19b9ff97d6ce5b494e57c6a3 |
IEDL.DBID | RPM |
ISSN | 1932-6203 |
IngestDate | Fri Nov 26 17:12:27 EST 2021 Tue Oct 22 15:16:03 EDT 2024 Tue Sep 17 21:18:16 EDT 2024 Fri Oct 25 05:04:29 EDT 2024 Sat Nov 09 13:09:49 EST 2024 Tue Nov 19 21:04:42 EST 2024 Tue Nov 12 22:54:47 EST 2024 Thu Aug 01 20:27:47 EDT 2024 Thu Aug 01 19:50:36 EDT 2024 Tue Aug 20 21:52:39 EDT 2024 Fri Nov 22 00:54:46 EST 2024 Tue Oct 15 23:48:20 EDT 2024 |
IsDoiOpenAccess | true |
IsOpenAccess | true |
IsPeerReviewed | true |
IsScholarly | true |
Issue | 10 |
Language | English |
License | This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited. Creative Commons Attribution License |
LinkModel | DirectLink |
MergedId | FETCHMERGED-LOGICAL-c692t-7a273c1c667ff0c3756ab1f5713255260569ecaa19b9ff97d6ce5b494e57c6a3 |
Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 Competing Interests: The authors have declared that no competing interests exist. Conceived and designed the experiments: NM-M EM-A JB JAM-M. Performed the experiments: NM-M EM-A. Analyzed the data: NM-M EM-A JB JAM-M. Contributed to the writing of the manuscript: NM-M EM-A JB JAM-M. |
OpenAccessLink | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4213061/ |
PMID | 25354038 |
PQID | 1618152414 |
PQPubID | 1436336 |
ParticipantIDs | plos_journals_1618152414 doaj_primary_oai_doaj_org_article_9be61ac788b34c69a3cba47d59973e47 pubmedcentral_primary_oai_pubmedcentral_nih_gov_4213061 proquest_miscellaneous_1619313808 proquest_journals_1618152414 gale_infotracmisc_A417323302 gale_infotracacademiconefile_A417323302 gale_incontextgauss_ISR_A417323302 gale_incontextgauss_IOV_A417323302 gale_healthsolutions_A417323302 crossref_primary_10_1371_journal_pone_0111685 pubmed_primary_25354038 |
PublicationCentury | 2000 |
PublicationDate | 2014-10-29 |
PublicationDateYYYYMMDD | 2014-10-29 |
PublicationDate_xml | – month: 10 year: 2014 text: 2014-10-29 day: 29 |
PublicationDecade | 2010 |
PublicationPlace | United States |
PublicationPlace_xml | – name: United States – name: San Francisco – name: San Francisco, USA |
PublicationTitle | PloS one |
PublicationTitleAlternate | PLoS One |
PublicationYear | 2014 |
Publisher | Public Library of Science Public Library of Science (PLoS) |
Publisher_xml | – name: Public Library of Science – name: Public Library of Science (PLoS) |
References | 23591818 - J Cell Sci. 2013 Jun 15;126(Pt 12):2641-55 9788882 - J Cell Sci. 1998 Nov;111 ( Pt 22):3411-25 9388229 - J Biol Chem. 1997 Dec 5;272(49):30848-51 22212660 - Prog Lipid Res. 2012 Apr;51(2):71-81 9133344 - Curr Biol. 1997 May 1;7(5):301-7 2178778 - Cell. 1990 Mar 9;60(5):821-36 22806901 - Histol Histopathol. 2012 Sep;27(9):1143-53 17274796 - Traffic. 2007 Apr;8(4):359-68 22562055 - Biochim Biophys Acta. 2012 Aug;1821(8):1078-88 12694560 - Traffic. 2003 Apr;4(4):214-21 16365634 - Nat Rev Mol Cell Biol. 2006 Jan;7(1):9-19 15502824 - Nat Cell Biol. 2004 Nov;6(11):1071-81 19037109 - Mol Biol Cell. 2009 Feb;20(3):780-90 15697235 - Biochemistry. 2005 Feb 15;44(6):2097-102 21169361 - J Biol Chem. 2011 Feb 25;286(8):6832-43 17360540 - Proc Natl Acad Sci U S A. 2007 Mar 13;104(11):4425-30 18776900 - Nat Cell Biol. 2008 Oct;10(10):1146-53 11294898 - Mol Biol Cell. 2001 Apr;12(4):943-55 17567948 - Mol Biol Cell. 2007 Sep;18(9):3250-63 15569243 - Traffic. 2005 Jan;6(1):32-44 20735042 - J Med Chem. 2010 Sep 23;53(18):6706-19 12960426 - Mol Biol Cell. 2003 Dec;14(12):4885-95 9395408 - Curr Biol. 1997 Mar 1;7(3):191-201 12388557 - J Biol Chem. 2002 Dec 13;277(50):48965-75 18693248 - J Biol Chem. 2008 Oct 10;283(41):27717-23 14654841 - Nature. 2003 Dec 4;426(6966):563-6 16956762 - Trends Cell Biol. 2006 Oct;16(10):e1-4 19840796 - FEBS Lett. 2009 Dec 3;583(23):3847-56 20605711 - Curr Opin Cell Biol. 2010 Aug;22(4):430-6 12429836 - Mol Biol Cell. 2002 Nov;13(11):3930-42 21725317 - Nat Cell Biol. 2011 Aug;13(8):996-1003 21936578 - Chem Rev. 2011 Oct 12;111(10):6064-119 11736663 - Biochem J. 2001 Dec 15;360(Pt 3):707-15 23812035 - Histochem Cell Biol. 2013 Sep;140(3):327-39 11748249 - J Cell Biol. 2001 Dec 24;155(7):1199-212 12925777 - Mol Biol Cell. 2003 Aug;14(8):3459-69 16574237 - Prog Lipid Res. 2006 May;45(3):250-78 17085061 - Cell Biol Int. 2007 Feb;31(2):148-55 21502307 - Cold Spring Harb Perspect Biol. 2011 Jul;3(7). pii: a005181. doi: 10.1101/cshperspect.a005181 24867214 - Elife. 2014;3. doi: 10.7554/eLife.02009 22339628 - Biochemistry (Mosc). 2012 Jan;77(1):1-14 11208136 - Traffic. 2000 Jun;1(6):504-11 12808027 - Mol Biol Cell. 2003 Jun;14(6):2250-61 19362164 - Biochim Biophys Acta. 2009 Sep;1791(9):881-8 21447092 - Acta Physiol (Oxf). 2012 Feb;204(2):219-26 2999135 - J Biol Chem. 1985 Dec 15;260(29):15762-70 18331383 - Traffic. 2008 May;9(5):786-97 20637885 - Semin Cell Dev Biol. 2011 Feb;22(1):3-9 19268584 - Bioorg Med Chem Lett. 2009 Apr 1;19(7):1916-20 21600869 - Biochim Biophys Acta. 2011 Sep;1808(9):2119-27 7045286 - J Neurochem. 1982 Aug;39(2):299-305 3032105 - Arch Biochem Biophys. 1987 Mar;253(2):453-61 17651957 - Curr Opin Cell Biol. 2007 Aug;19(4):426-35 14744428 - Cell. 2004 Jan 23;116(2):153-66 Z Freyberg (ref32) 2002; 13 JA Martínez-Menárguez (ref1) 2013; 2013 E Martínez-Alonso (ref8) 2013; 140 K Bi (ref24) 1997; 7 R Lavieri (ref34) 2010; 53 V Haucke (ref11) 2007; 19 MJ López-Andreo (ref29) 2003; 14 JA Lewis (ref33) 2009; 19 J Bigay (ref22) 2003; 426 WJ Brown (ref26) 2008; 9 J Moelleken (ref52) 2007; 104 X Peng (ref37) 2012; 204 GV Beznoussenko (ref55) 2014; 3 L Asp (ref15) 2009; 20 E Gutiérrez-Martínez (ref17) 2013; 126 RS Polishchuk (ref9) 2009; 583 Z Nie (ref47) 2002; 277 P De Figueiredo (ref13) 2000; 1 TR Graham (ref12) 2010; 22 I Fernández-Ulibarri (ref16) 2007; 18 KD Ha (ref41) 2012; 1821 J-H Jang (ref36) 2012; 51 WC Colley (ref40) 1997; 7 TR Pettitt (ref51) 2001; 306 EE Kooijman (ref38) 2009; 1791 J Lippincott-Schwartz (ref4) 1990; 60 O Koul (ref25) 1987; 253 R Chalifour (ref42) 1982; 39 B Antonny (ref21) 1997; 272 R García-Mata (ref5) 2003; 14 J-S Yang (ref19) 2011; 13 Y Shiba (ref46) 2012; 27 J Lippincott-Schwartz (ref35) 2006; 16 J Klumperman (ref43) 1998; 111 J-S Yang (ref18) 2008; 10 J Bonifacino (ref2) 2004; 116 X Wang (ref30) 2006; 45 Z Freyberg (ref31) 2001; 12 H Kim (ref39) 2007; 31 T Kurooka (ref48) 2011; 286 J Lanoix (ref53) 2001; 155 E Martínez-Alonso (ref6) 2005; 6 P González-Rubio (ref49) 2011; 1808 E Martínez-Alonso (ref7) 2007; 8 MP East (ref45) 2011; 22 YS Kolesnikov (ref44) 2012; 77 D De Chaffoy de Courcelles (ref28) 1985; 260 M Krauss (ref20) 2008; 283 EE Kooijman (ref50) 2005; 44 PE Selvy (ref23) 2011; 111 J Zimmerberg (ref10) 2006; 7 A1 Trucco (ref54) 2004; 6 J Klumperman (ref3) 2011; 3 WJ Brown (ref14) 2003; 4 D Drecktrah (ref27) 2003; 14 |
References_xml | – volume: 104 start-page: 4425 year: 2007 ident: ref52 article-title: Differential localization of coatomer complex isoforms within the Golgi apparatus publication-title: Proc Natl Acad Sci U S A doi: 10.1073/pnas.0611360104 contributor: fullname: J Moelleken – volume: 4 start-page: 214 year: 2003 ident: ref14 article-title: Phospholipase A2 (PLA2) enzymes in membrane trafficking: mediators of membrane shape and function publication-title: Traffic doi: 10.1034/j.1600-0854.2003.00078.x contributor: fullname: WJ Brown – volume: 39 start-page: 299 year: 1982 ident: ref42 article-title: Fatty acid activation and temperature perturbation of rat brain microsomal phospholipase D. J Neurochem contributor: fullname: R Chalifour – volume: 19 start-page: 1916 year: 2009 ident: ref33 article-title: Design and synthesis of isoform-selective phospholipase D (PLD) inhibitors. Part I: Impact of alternative halogenated privileged structures for PLD1 specificity publication-title: Bioorg Med Chem Lett doi: 10.1016/j.bmcl.2009.02.057 contributor: fullname: JA Lewis – volume: 140 start-page: 327 year: 2013 ident: ref8 article-title: Golgi tubules: their structure, formation and role in intra-Golgi transport publication-title: Histochem Cell Biol doi: 10.1007/s00418-013-1114-9 contributor: fullname: E Martínez-Alonso – volume: 286 start-page: 6832 year: 2011 ident: ref48 article-title: Dual regulation of RA-RhoGAP activity by phosphatidic acid and Rap1 during neurite outgrowth publication-title: J Biol Chem doi: 10.1074/jbc.M110.183772 contributor: fullname: T Kurooka – volume: 31 start-page: 148 year: 2007 ident: ref39 article-title: Differential expression of phospholipases D1 and D2 in mouse tissues publication-title: Cell Biol Int doi: 10.1016/j.cellbi.2006.09.020 contributor: fullname: H Kim – volume: 3 year: 2014 ident: ref55 article-title: Transport of soluble proteins through the Golgi occurs by diffusion via continuities across cisternae publication-title: Elife doi: 10.7554/eLife.02009 contributor: fullname: GV Beznoussenko – volume: 2013 start-page: 1 year: 2013 ident: ref1 article-title: Intra-Golgi transport: roles for vesicles, tubules, and cisternae publication-title: ISRN Cell Biol doi: 10.1155/2013/126731 contributor: fullname: JA Martínez-Menárguez – volume: 426 start-page: 563 year: 2003 ident: ref22 article-title: Lipid packing sensed by ArfGAP1 couples COPI coat disassembly to membrane bilayer curvature publication-title: Nature doi: 10.1038/nature02108 contributor: fullname: J Bigay – volume: 16 start-page: e1 year: 2006 ident: ref35 article-title: Insights into COPI coat assembly and function in living cells publication-title: Trends Cell Biol doi: 10.1016/j.tcb.2006.08.008 contributor: fullname: J Lippincott-Schwartz – volume: 1 start-page: 504 year: 2000 ident: ref13 article-title: Phospholipase A2 antagonists inhibit constitutive retrograde membrane traffic to the endoplasmic reticulum publication-title: Traffic doi: 10.1034/j.1600-0854.2000.010608.x contributor: fullname: P De Figueiredo – volume: 18 start-page: 3250 year: 2007 ident: ref16 article-title: Diacylglycerol is required for the formation of COPI vesicles in the Golgi-to-ER transport pathway publication-title: Mol Biol Cell doi: 10.1091/mbc.E07-04-0334 contributor: fullname: I Fernández-Ulibarri – volume: 14 start-page: 2250 year: 2003 ident: ref5 article-title: ADP-ribosylation factor/COPI-dependent events at the endoplasmic reticulum-Golgi interface are regulated by the guanine nucleotide exchange factor GBF1 publication-title: Mol Biol Cell doi: 10.1091/mbc.E02-11-0730 contributor: fullname: R García-Mata – volume: 1821 start-page: 1078 year: 2012 ident: ref41 article-title: Regulation of the Golgi complex by phospholipid remodeling enzymes publication-title: Biochim Biophys Acta doi: 10.1016/j.bbalip.2012.04.004 contributor: fullname: KD Ha – volume: 126 start-page: 2641 year: 2013 ident: ref17 article-title: Lipid phosphate phosphatase 3 participates in transport carrier formation and protein trafficking in the early secretory pathway publication-title: J Cell Sci doi: 10.1242/jcs.117705 contributor: fullname: E Gutiérrez-Martínez – volume: 77 start-page: 1 year: 2012 ident: ref44 article-title: Molecular structure of phospholipase D and regulatory mechanisms of its activity in plant and animal cells publication-title: Biochem Biokhimiia doi: 10.1134/S0006297912010014 contributor: fullname: YS Kolesnikov – volume: 60 start-page: 821 year: 1990 ident: ref4 article-title: Microtubule-dependent retrograde transport of proteins into the ER in the presence of brefeldin a suggests an ER recycling pathway publication-title: Cell doi: 10.1016/0092-8674(90)90096-W contributor: fullname: J Lippincott-Schwartz – volume: 155 start-page: 1199 year: 2001 ident: ref53 article-title: Sorting of Golgi resident proteins into different subpopulations of COPI vesicles: a role for ArfGAP1 publication-title: J Cell Biol doi: 10.1083/jcb.200108017 contributor: fullname: J Lanoix – volume: 7 start-page: 9 year: 2006 ident: ref10 article-title: How proteins produce cellular membrane curvature publication-title: Nat Rev Mol Cell Biol doi: 10.1038/nrm1784 contributor: fullname: J Zimmerberg – volume: 583 start-page: 3847 year: 2009 ident: ref9 article-title: Shaping tubular carriers for intracellular membrane transport publication-title: FEBS Lett doi: 10.1016/j.febslet.2009.10.031 contributor: fullname: RS Polishchuk – volume: 13 start-page: 996 year: 2011 ident: ref19 article-title: COPI acts in both vesicular and tubular transport publication-title: Nat Cell Biol doi: 10.1038/ncb2273 contributor: fullname: J-S Yang – volume: 272 start-page: 30848 year: 1997 ident: ref21 article-title: Activation of ADP-ribosylation factor 1 GTPase-activating protein by phosphatidylcholine-derived diacylglycerols publication-title: J Biol Chem doi: 10.1074/jbc.272.49.30848 contributor: fullname: B Antonny – volume: 260 start-page: 15762 year: 1985 ident: ref28 article-title: R 59 022, a diacylglycerol kinase inhibitor. Its effect on diacylglycerol and thrombin-induced C kinase activation in the intact platelet publication-title: J Biol Chem doi: 10.1016/S0021-9258(17)36324-X contributor: fullname: D De Chaffoy de Courcelles – volume: 7 start-page: 301 year: 1997 ident: ref24 article-title: Phosphatidic acid formation by phospholipase D is required for transport from the endoplasmic reticulum to the Golgi complex publication-title: Curr Biol doi: 10.1016/S0960-9822(06)00153-9 contributor: fullname: K Bi – volume: 19 start-page: 426 year: 2007 ident: ref11 article-title: Lipids and lipid modifications in the regulation of membrane traffic publication-title: Curr Opin Cell Biol doi: 10.1016/j.ceb.2007.06.003 contributor: fullname: V Haucke – volume: 20 start-page: 780 year: 2009 ident: ref15 article-title: Early stages of Golgi vesicle and tubule formation require diacylglycerol publication-title: Mol Biol Cell doi: 10.1091/mbc.E08-03-0256 contributor: fullname: L Asp – volume: 45 start-page: 250 year: 2006 ident: ref30 article-title: Signaling functions of phosphatidic acid publication-title: Prog Lipid Res doi: 10.1016/j.plipres.2006.01.005 contributor: fullname: X Wang – volume: 12 start-page: 943 year: 2001 ident: ref31 article-title: Intracellular localization of phospholipase D1 in mammalian cells publication-title: Mol Biol Cell doi: 10.1091/mbc.12.4.943 contributor: fullname: Z Freyberg – volume: 27 start-page: 1143 year: 2012 ident: ref46 article-title: ArfGAP1 function in COPI mediated membrane traffic: Currently debated models and comparison to other coat-binding ArfGAPs publication-title: Histol Histopathol contributor: fullname: Y Shiba – volume: 111 start-page: 3411 year: 1998 ident: ref43 article-title: The recycling pathway of protein ERGIC-53 and dynamics of the ER-Golgi intermediate compartment publication-title: J Cell Sci doi: 10.1242/jcs.111.22.3411 contributor: fullname: J Klumperman – volume: 1791 start-page: 881 year: 2009 ident: ref38 article-title: Biophysics and function of phosphatidic acid: a molecular perspective publication-title: Biochim Biophys Acta doi: 10.1016/j.bbalip.2009.04.001 contributor: fullname: EE Kooijman – volume: 277 start-page: 48965 year: 2002 ident: ref47 article-title: AGAP1, an endosome-associated, phosphoinositide-dependent ADP-ribosylation factor GTPase-activating protein that affects actin cytoskeleton publication-title: J Biol Chem doi: 10.1074/jbc.M202969200 contributor: fullname: Z Nie – volume: 6 start-page: 1071 year: 2004 ident: ref54 article-title: Secretory traffic triggers the formation of tubular continuities across Golgi sub-compartments publication-title: Nat Cell Biol doi: 10.1038/ncb1180 contributor: fullname: A1 Trucco – volume: 14 start-page: 4885 year: 2003 ident: ref29 article-title: The simultaneous production of phosphatidic acid and diacylglycerol is essential for the translocation of protein kinase Cepsilon to the plasma membrane in RBL-2H3 cells publication-title: Mol Biol Cell doi: 10.1091/mbc.E03-05-0295 contributor: fullname: MJ López-Andreo – volume: 6 start-page: 32 year: 2005 ident: ref6 article-title: Structure and dynamics of the Golgi complex at 15°C: low temperature induces the formation of Golgi-derived tubules publication-title: Traffic doi: 10.1111/j.1600-0854.2004.00242.x contributor: fullname: E Martínez-Alonso – volume: 22 start-page: 430 year: 2010 ident: ref12 article-title: Interplay of proteins and lipids in generating membrane curvature publication-title: Curr Opin Cell Biol doi: 10.1016/j.ceb.2010.05.002 contributor: fullname: TR Graham – volume: 8 start-page: 359 year: 2007 ident: ref7 article-title: Low-temperature-induced Golgi tubules are transient membranes enriched in molecules regulating intra-Golgi transport publication-title: Traffic doi: 10.1111/j.1600-0854.2006.00533.x contributor: fullname: E Martínez-Alonso – volume: 111 start-page: 6064 year: 2011 ident: ref23 article-title: Phospholipase D: enzymology, functionality, and chemical modulation publication-title: Chem Rev doi: 10.1021/cr200296t contributor: fullname: PE Selvy – volume: 7 start-page: 191 year: 1997 ident: ref40 article-title: Phospholipase D2, a distinct phospholipase D isoform with novel regulatory properties that provokes cytoskeletal reorganization publication-title: Curr Biol doi: 10.1016/S0960-9822(97)70090-3 contributor: fullname: WC Colley – volume: 53 start-page: 6706 year: 2010 ident: ref34 article-title: Design, synthesis, and biological evaluation of halogenated N-(2-(4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)ethyl)benzamides: discovery of an isoform-selective small molecule phospholipase D2 inhibitor publication-title: J Med Chem doi: 10.1021/jm100814g contributor: fullname: R Lavieri – volume: 51 start-page: 71 year: 2012 ident: ref36 article-title: Understanding of the roles of phospholipase D and phosphatidic acid through their binding partners publication-title: Prog Lipid Res doi: 10.1016/j.plipres.2011.12.003 contributor: fullname: J-H Jang – volume: 44 start-page: 2097 year: 2005 ident: ref50 article-title: Spontaneous curvature of phosphatidic acid and lysophosphatidic acid publication-title: Biochemistry doi: 10.1021/bi0478502 contributor: fullname: EE Kooijman – volume: 306 start-page: 707 year: 2001 ident: ref51 article-title: Phospholipase D1b and D2a generate structurally identical phosphatidic acid species in mammalian cells publication-title: Biochem J doi: 10.1042/bj3600707 contributor: fullname: TR Pettitt – volume: 3 start-page: a005181 year: 2011 ident: ref3 article-title: Architecture of the mammalian Golgi publication-title: Cold Spring Harb Perspect Biol doi: 10.1101/cshperspect.a005181 contributor: fullname: J Klumperman – volume: 13 start-page: 3930 year: 2002 ident: ref32 article-title: Phospholipase D2 is localised to the rims of the Golgi apparatus in mammalian cells publication-title: Mol Biol Cell doi: 10.1091/mbc.02-04-0059 contributor: fullname: Z Freyberg – volume: 253 start-page: 453 year: 1987 ident: ref25 article-title: Modulation of rat brain cytosolic phosphatidate phosphohydrolase: Effect of cationic amphiphilic drugs and divalent cations publication-title: Arch Biochem Biophys doi: 10.1016/0003-9861(87)90199-8 contributor: fullname: O Koul – volume: 1808 start-page: 2119 year: 2011 ident: ref49 article-title: Amphipathic-Lipid-Packing-Sensor interactions with lipids assessed by atomistic molecular dynamics publication-title: Biochim Biophys Acta doi: 10.1016/j.bbamem.2011.05.006 contributor: fullname: P González-Rubio – volume: 14 start-page: 3459 year: 2003 ident: ref27 article-title: Inhibition of a Golgi complex lysophospholipid acyltransferase induces membrane tubule formation and retrograde trafficking publication-title: Mol Biol Cell doi: 10.1091/mbc.E02-11-0711 contributor: fullname: D Drecktrah – volume: 116 start-page: 153 year: 2004 ident: ref2 article-title: The mechanisms of vesicle budding and fusion publication-title: Cell doi: 10.1016/S0092-8674(03)01079-1 contributor: fullname: J Bonifacino – volume: 204 start-page: 219 year: 2012 ident: ref37 article-title: Mammalian phospholipase D physiological and pathological roles publication-title: Acta Physiol doi: 10.1111/j.1748-1716.2011.02298.x contributor: fullname: X Peng – volume: 10 start-page: 1146 year: 2008 ident: ref18 article-title: COPI vesicle fission: a role for phosphatidic acid and insight into Golgi maintenance publication-title: Nat Cell Biol doi: 10.1038/ncb1774 contributor: fullname: J-S Yang – volume: 22 start-page: 3 year: 2011 ident: ref45 article-title: Models for the functions of Arf GAPs publication-title: Semin Cell Dev Biol doi: 10.1016/j.semcdb.2010.07.002 contributor: fullname: MP East – volume: 283 start-page: 27717 year: 2008 ident: ref20 article-title: Arf1-GTP-induced tubule formation suggests a function of Arf family proteins in curvature acquisition at sites of vesicle budding publication-title: J Biol Chem doi: 10.1074/jbc.M804528200 contributor: fullname: M Krauss – volume: 9 start-page: 786 year: 2008 ident: ref26 article-title: The lysophospholipid acyltransferase antagonist CI-976 inhibits a late step in COPII vesicle budding publication-title: Traffic doi: 10.1111/j.1600-0854.2008.00711.x contributor: fullname: WJ Brown |
SSID | ssj0053866 |
Score | 2.2095828 |
Snippet | Lipids and lipid-modifying enzymes play a key role in the biogenesis, maintenance and fission of transport carriers in the secretory and endocytic pathways. In... |
SourceID | plos doaj pubmedcentral proquest gale crossref pubmed |
SourceType | Open Website Open Access Repository Aggregation Database Index Database |
StartPage | e111685 |
SubjectTerms | Acids Analysis Biology Biology and Life Sciences Brefeldin A Depletion Employee recruitment Endoplasmic reticulum Enzymatic activity Enzymes Golgi apparatus GTPase-Activating Proteins - genetics GTPase-Activating Proteins - metabolism HeLa Cells Histology Humans Kinases Lipids Low temperature Medical schools Membranes Molecular modelling Overexpression Phosphatidic acid Phosphatidic Acids - metabolism Phospholipase Phospholipase D - antagonists & inhibitors Phospholipase D - genetics Phospholipase D - metabolism Phospholipase D2 Phospholipases Physiological aspects Protein Transport Proteins Recruitment Regulation trans-Golgi Network - metabolism Transport Tubules |
SummonAdditionalLinks | – databaseName: DOAJ Directory of Open Access Journals dbid: DOA link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwrV3db9MwELdQn3hBjAELjGEQEvCQLf6IXT-Wj20gAROMaW-W7ThbpCqploa_n3PiRg2aBA-8Vb2r296X79q73yH0ijsI-kKYdG4JSyHgkdTQvEgz64ynThVZD8fw5as4_ck_X-aXW6u-Qk_YAA88CO5IWS-IcVCpWQYHK8OcNVwWuVKSeT7MkWd0U0wNMRi8WIg4KMckOYp6OVw1tT8M29VF2J28dRH1eP1jVJ6tlk17W8r5Z-fk1lV0fB_dizkkXgyffQfd8fUDtBO9tMVvIpT02110cXbdtCsIcNUKbiv8geKqxVUNIemXL-ABhvQPj_OLuCnxSbO8qvC6s90SjjJ1AW9TnizOCIbQeNNVfVP6Q3R-_PH8_WkaNymkIDG6TqWBLMUR0Issy8wxmQtjSZlDhQolRShphPLOGKKsKkslC-F8brniPpdOGPYIzWoQ3R7CBWN5MYckyzrCibEBAM9ByceFybIidwlKN1LVqwEvQ_d_mkmoMwbx6KAFHbWQoHdB9CNvQLvunwAb0NEG9N9sIEHPg-L0MDo6-qxecCIZZSyjCXrZcwTEizq01FyZrm31p28X_8D04_uE6XVkKhswAWfiGAN8p4CkNeHcn3CC37oJeS-Y2UYqrQ6rCyCb4oTDKzemdzv5xUgOh4Y2udo3Xc-jGGHzbJ6gx4OljpKlefiJjwFFTmx4Ivoppa6ue8BxTiHTEeTJ_9DVU3QXck4ern-q9tFsfdP5Z5DXre1B78K_AXOrSTI priority: 102 providerName: Directory of Open Access Journals – databaseName: ProQuest Technology Collection dbid: 8FG link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwjV3db9MwELegCIkXxMbHCgMMQgIessWxY9dPqHy0KxIwwZj2FtlO0lWqkrA0SPz33CVOWdCEeO1dkua-fOecf0fIC-Eg6EtpgollPICAxwITxWkQWmeyyOk0bOEYPn2WR9_Fx7P4zG-41b6tso-JbaBOS4d75IcI7A5rjWDiTfUjwKlR-HXVj9C4Tm6wSEls6ZvM5n0kBl-W0h-X44odeu0cVGWRHeCMdYkTlC8tRy1q_zY2j6p1WV-VeP7dP3lpQZrdIbd9Jkmnnep3yLWs2CU3u9mSv3bJjvfamr7y0NKv75LT4_OyriDgrSpYvej7iC5quiggRP3MUroqKKSDdNafZ6RlTuflermiJ41t1nArU6TwwHw-PWYUE85m1Tap3yMnsw8n744CP1khcFJHm0AZyFocAz2pPA8dV7E0luUxVKxQYmCJI3XmjGHa6jzXKpUui63QIouVk4bfJ6MChLhHaMp5nE4g6bKOCWYsAuI5KAGFNGGYxm5Mgl6-SdXhZyTtRzQFdUcnqAT1kXh9jMlbVMKWF9Gv2x_Ki2XinSnRNpPMOKjeLQdj04Y7a4RKY60Vz4Qak6eowqQ7Srr14WQqmOIR52E0Js9bDkTAKLDFZmmauk4WX07_g-nb1wHTS8-Ul2AMzvhjDfBOiKw14NwfcIIfuwF5Dw2ul0qd_LF4uLI3wqvJz7ZkvCm2zRVZ2bQ8mjM-CSdj8qCz2a1koxi3_DhQ1MCaB6IfUorVeQtALiLIfCR7-O-_9YjcguxS4EIf6X0y2lw02WPI4Db2SeumvwHkoUKy priority: 102 providerName: ProQuest – databaseName: Scholars Portal Open Access Journals dbid: M48 link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwjV3db9MwELdGeeEFMb5WGGAQEvCQKf6uHxAqH92KNJigm_YW2Y7TVaqS0jQI_nvOaRIRVKS99i6O-vOd_bv4fIfQS-5g0ZfSRCNLWAQLHokMFWkUW2c8dTqN63IMp1_kyTn_fCku91Dbs7UBsNwZ2oV-Uufr5dGvH7_fgcO_rbs2KNI-dLQqcn8UeqfLkbiBblLYG0OS1ynvzhXAu-vTy8BaIklj1lym-98ovc2qrunfrdyD1bIod9HSf7Mr_9quJnfQ7YZn4vHWMPbRns_vov3Gk0v8uik3_eYeuji7KsoV4LBYwY6GP1I8LfE0h2Xrp0_xIsdAEfGkveOIiwwfF8v5As8qWy1hKJOn8JrseHxGcCCh1aJOXL-PZpNPsw8nUdNtIXJS002kDDAZR2DuVJbFjikhjSWZgCgWwo4Q9kjtnTFEW51lWqXSeWG55l4oJw17gAY5QHeAcMqYSEdAxKwjnBgbiuQ5CAu5NHGcCjdEUYtqstrW1EjqgzUFscgWniTMQtLMwhC9D9B3uqEidv1DsZ4njYMl2npJjIOI3jIwQG2Ys4arVGitmOdqiJ6FiUu210s7v07GnChGGYvpEL2oNUJVjDyk3cxNVZbJ9OvFNZS-f-spvWqUsgJMwJnmqgP8p1Btq6d52NME33Y98UEwsxaVMgntDYBxccLhydb0doufd-IwaEily31R1TqaETaKR0P0cGupHbJUhM-ADCSqZ8M96PuSfHFVFyXnFNiQJI-ug89jdAt4Jw8UgOpDNNisK_8EuN3GPq3d9Q8bbEl6 priority: 102 providerName: Scholars Portal |
Title | Phospholipase D2 is involved in the formation of Golgi tubules and ArfGAP1 recruitment |
URI | https://www.ncbi.nlm.nih.gov/pubmed/25354038 https://www.proquest.com/docview/1618152414 https://search.proquest.com/docview/1619313808 https://pubmed.ncbi.nlm.nih.gov/PMC4213061 https://doaj.org/article/9be61ac788b34c69a3cba47d59973e47 http://dx.doi.org/10.1371/journal.pone.0111685 |
Volume | 9 |
hasFullText | 1 |
inHoldings | 1 |
isFullTextHit | |
isPrint | |
link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV3Nb9MwFLe2cuGCGF_LGMUgJOCQNo4dOz52Ze2K1FGNMu0W2U7SVeqSaGn5-3nOR7WgHRAXH-qXpH3fL33vZ4Q-MQNOn3PlhppQFxwecZUfxK6njUp8I2OvgmOYX_KLX-z7TXBzgIJ2FqZq2jd6Pcg2d4NsfVv1VhZ3Ztj2iQ0X8zHzwfNyMjxEhxB-2xK9dr9gwJw3M3JUkGEjkkGRZ8nAHqzOQ3tajR_YFx52KuVBOKpQ-_e-uVds8vKxxPPv_skHAWnyHD1rMkk8qr_xETpIshfoqLHVEn9pAKW_vkTXi9u8LMDNrQuIWfibj2clnmXgmH4nMV5nGJJAPGmnGHGe4mm-Wa3xcqd3wAusshgek05HC4JtmrlbV63pr9Bycr4cX7jNeQqu4dLfukJBrmIISEekqWeoCLjSJA2gToXCwhY2XCZGKSK1TFMpYm6SQDPJkkAYruhr1MuAi8cIx5QGcQipljaEEaUtDJ6Bwo9x5XlxYBzktlyNiho1I6r-OhNQbdTsiaxAokYgDjqzrN_TWszr6oP8fhU1ko-kTjhRBmp2TUHFpKJGKybiQEpBEyYc9N4KLqoHSPeWG40YEdSn1PMd9LGisLgXmW2sWaldWUazH9f_QPTzqkP0uSFKc1ABo5phBvhNFk-rQ3naoQTrNZ3tY6tmLVfKyB5gADkVIwyubFXv8e0P-217U9sslyX5rqKRlNDQCx30ptbUPWdbvXeQ6Ohwh_XdHbDCCna8sbqT_77yLXoK6Sazkd-Xp6i3vd8l7yCl2-o-GPKNgDUcE7tOpn305Oz8cnHVr16SwDpnYb8y9D_hxU6x |
link.rule.ids | 230,314,727,780,784,864,885,2102,2221,12056,12223,12765,21388,24318,27924,27925,31719,31720,33266,33267,33373,33374,33744,33745,43310,43579,43600,43805,53791,53793,73745,74014,74035,74302 |
linkProvider | National Library of Medicine |
linkToHtml | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwjV3db9MwELegE4IXxMbHCoMZhAQ8ZItjx66fUAfbWthKNbppb5HtJF2lKglLg8R_zzlxyoImxGvvkjT35Tvn_DuE3jIDQZ9z5Q00oR4EPOKpIIw9XxuVBEbGfg3HcDrho3P25TK8dBtupWurbGNiHajj3Ng98n0L7A5rDSPsY_HDs1Oj7NdVN0LjLtqwyOlhD20cHE6mZ20sBm_m3B2Yo4LsO_3sFXmW7Nkp69zOUL6xINW4_evo3CuWeXlb6vl3B-WNJenoEXrockk8bJS_ie4k2Ra610yX_LWFNp3flvi9A5f-8BhdTK_ysoCQtyhg_cKfAzwu8TiDIPUzifEiw5AQ4qP2RCPOU3ycL-cLPKt0tYRbqSyGB6bHwynBNuWsFnWb-hM0OzqcfRp5braCZ7gMVp5QkLcYApoSaeobKkKuNElDqFmhyLBFDpeJUYpILdNUipibJNRMsiQUhiv6FPUyEOI2wjGlYTyAtEsbwojSFhLPQBHIuPL9ODR95LXyjYoGQSOqP6MJqDwaQUVWH5HTRx8dWCWseS3-df1Dfj2PnDtFUiecKAP1u6ZgblJRoxUTcSiloAkTfbRrVRg1h0nXXhwNGRE0oNQP-uhNzWExMDLbZDNXVVlG428X_8H0_azD9M4xpTkYg1HuYAO8k8XW6nDudDjBk02HvG0NrpVKGf2xebiyNcLbya_XZHtT2ziXJXlV80hKwDcGffSssdm1ZIPQbvpRoIiONXdE36Vki6sagpwFkPtw8vzff2sX3R_NTk-ik_Hk6wv0AHJNZpf9QO6g3uq6Sl5CPrfSr5zT_gaVb0cD |
linkToPdf | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwjV3db9MwELegE4gXxMbHCoMZhAQ8ZI1jx66fUMfWrXyUapRpb5HtJF2lKglLg8R_zzlxyoImxGvvmjb3-bvkfIfQa2Yg6HOuvKEm1IOARzwVhLHna6OSwMjYr8cxfJny0-_s40V44fqfStdW2cbEOlDHubHPyAd2sDvkGkbYIHVtEbOj8fvih2c3SNk3rW6dxm20BVnRD3po6_B4Ojtr4zJ4Nufu8BwVZOB0dVDkWXJgN65zu0_5WnKqZ_hvInWvWOXlTTD0727Ka-lp_ADdd7gSjxpD2Ea3kmwH3Wk2Tf7aQdvOh0v81g2afvcQnc8u87KA8LcsIJfhowBPSjzJIGD9TGK8zDCAQzxuTzfiPMUn-WqxxPNKVyu4lMpi-MH0ZDQj2MLPalm3rD9C8_Hx_MOp5_YseIbLYO0JBRjGENCaSFPfUBFypUkaQv0KBYcteLhMjFJEapmmUsTcJKFmkiWhMFzRx6iXgRB3EY4pDeMhQDBtCCNK2_F4BgpCxpXvx6HpI6-Vb1Q00zSi-pWagCqkEVRk9RE5ffTRoVXChtfOwq4_yK8WkXOtSOqEE2WgltcUTE8qarRiIg6lFDRhoo_2rQqj5mDpxqOjESOCBhRMpY9e1Rx2HkZmLWuhqrKMJl_P_4Pp21mH6Y1jSnMwBqPcIQe4Jztnq8O51-EErzYd8q41uFYqZfTH_uGbrRHeTH65IduL2ia6LMmrmkdSQof-sI-eNDa7kWwQ2geAFCiiY80d0Xcp2fKyHkfOAsBBnDz999_aR3fBX6PPk-mnZ-gewE5mEUAg91BvfVUlzwHarfUL57O_ARn2SzA |
openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Phospholipase+D2+Is+Involved+in+the+Formation+of+Golgi+Tubules+and+ArfGAP1+Recruitment&rft.jtitle=PloS+one&rft.au=Mart%C3%ADnez-Mart%C3%ADnez%2C+Narcisa&rft.au=Mart%C3%ADnez-Alonso%2C+Emma&rft.au=Ballesta%2C+Jos%C3%A9&rft.au=Mart%C3%ADnez-Men%C3%A1rguez%2C+Jos%C3%A9+A&rft.date=2014-10-29&rft.pub=Public+Library+of+Science&rft.issn=1932-6203&rft.eissn=1932-6203&rft.volume=9&rft.issue=10&rft_id=info:doi/10.1371%2Fjournal.pone.0111685&rft.externalDBID=ISR&rft.externalDocID=A417323302 |
thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=1932-6203&client=summon |
thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=1932-6203&client=summon |
thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=1932-6203&client=summon |