The Effects of Lung Protective Ventilation or Hypercapnic Acidosis on Gas Exchange and Lung Injury in Surfactant Deficient Rabbits - Hummler, Helmut D.; Banke, Katharina; Wolfson, Marla R.; Buonocore, Giuseppe; Ebsen, Michael; Bernhard, Wolfgang; Tsikas, Dimitrios; Fuchs, Hans (PloS one, 2016)
Keywords: Acidosis; Acidosis, Respiratory - etiology; Acidosis, Respiratory - physiopathology; Alveoli; Analysis; Animal models; Animals; Biology and Life Sciences; Biomarkers; Blood Gas Analysis; Bronchoalveolar lavage; Bronchoalveolar Lavage Fluid; Bronchus; Carbon dioxide; Critical care; Disease Models, Animal; Drug therapy; Engineering and Technology; Gas exchange; Hemodynamics; Histology; Hospitals; Hypercapnia; Hypercapnia - complications; Hypoventilation; Inflammation; Inflammatory response; Injury prevention; Interleukin; Interleukin 8; Laboratory animals; Lactic acid; Lung Injury - blood; Lung Injury - etiology; Lung Injury - pathology; Lung Injury - prevention & control; Lung Injury - therapy; Lungs; Mechanical ventilation; Medicine and Health Sciences; Newborn babies; Pediatric respiratory diseases; Pediatrics; pH effects; Physical Sciences; Pulmonary Surfactants; Rabbits; Respiration, Artificial - methods; Respiratory distress syndrome; Rodents; Surface active agents; Surfactants; Tidal Volume; Ventilation; Ventilators; Germany