Myeloid-specific deletion of NOX2 prevents the metabolic and neurologic consequences of high fat diet - Pepping, Jennifer K.; Vandanmagsar, Bolormaa; Fernandez-Kim, Sun-Ok; Zhang, Jingying; Mynatt, Randall L.; Bruce-Keller, Annadora J. (PloS one, 2017)
Keywords: Adipose tissue; Albinism; Animals; Biology and Life Sciences; Biomedical research; Body Composition - genetics; Body weight; Body Weight - genetics; Brain; Brain - physiology; Brain injury; Cardiovascular disease; Catalysis; Cell injury; Cell Lineage; Cholesterol; Clonal deletion; Cognition; CYBB protein; Data processing; Dementia; Diabetes; Diet; Diet, High-Fat - adverse effects; Gene Deletion; Gene expression; Gene Knockout Techniques; Genetic aspects; Glucose; Head injuries; Health aspects; High fat diet; Infiltration; Inflammation; Inhibition; Insulin resistance; Intra-Abdominal Fat - metabolism; Laboratory animals; Lipids; Macrophages; Medicine and Health Sciences; Membrane Glycoproteins - deficiency; Membrane Glycoproteins - genetics; Metabolic syndrome; Mice; Monocytes; Myeloid Cells - metabolism; NAD(P)H oxidase; NADPH Oxidase 2; NADPH Oxidases - deficiency; NADPH Oxidases - genetics; NMR; Nuclear magnetic resonance; Nutrition research; Obesity; Oxidases; Oxidizing agents; Pathogenesis; Pathology; Physiological aspects; Rodents; Stem cells; Baton Rouge Louisiana; United States--US