Safety and preliminary efficacy of orally administered lyophilized fecal microbiota product compared with frozen product given by enema for recurrent Clostridium difficile infection: A randomized clinical trial - Jiang, Zhi-Dong; Jenq, Robert R.; Ajami, Nadim J.; Petrosino, Joseph F.; Alexander, Ashley A.; Ke, Shi; Iqbal, Tehseen; DuPont, Andrew W.; Muldrew, Kenneth; Shi, Yushu; Peterson, Christine; Do, Kim-Anh; et al. (PloS one, 2018)
Keywords: Administration, Oral; Adult; Adults; Aged; Aged, 80 and over; Analysis; Antibiotics; Bacteria; Biology and Life Sciences; Cancer; Capsules; Care and treatment; Clinical trials; Clostridium difficile - isolation & purification; Clostridium infections; Clostridium Infections - therapy; Colon; Colonoscopy; Comparative analysis; Cryopreservation; Effectiveness; Enema; Enema - adverse effects; Enema - methods; Epidemiology; Fecal Microbiota Transplantation - adverse effects; Fecal Microbiota Transplantation - methods; Fecal microflora; Feces; Female; Freeze Drying; Health care; Humans; Infections; Infectious diseases; Male; Medicine and Health Sciences; Microbiomes; Microbiota; Middle Aged; Oral administration; Pathogens; Product safety; Public health; Rectum; Recurrent infection; Safety; Spore-forming bacteria; Transplantation; Transplants & implants; Treatment outcome; Virology; Young Adult; United States--US