Genetic Diversity of Cryptosporidium in Children in an Urban Informal Settlement of Nairobi, Kenya

• Published in: PloS one Vol. 10; no. 12; p. e0142055
• Main Authors: Mbae, Cecilia, Mulinge, Erastus, Waruru, Anthony, Ngugi, Benjamin, Wainaina, James, Kariuki, Samuel
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 21.12.2015; Public Library of Science (PLoS)
• Subjects: Ambulatory care facilities; Analysis; Animals; Bacteria; Base Sequence; Child, Preschool; Children; Cryptosporidiosis - epidemiology; Cryptosporidiosis - genetics; Cryptosporidium; Cryptosporidium - classification; Cryptosporidium - genetics; Cryptosporidium - isolation & purification; Cryptosporidium hominis; Cryptosporidium meleagridis; Deoxyribonucleic acid; Diarrhea; DNA; Enterocytozoon bieneusi; Epidemiology; Female; Gene polymorphism; Gene sequencing; Genetic aspects; Genetic diversity; Genetic polymorphisms; Genetic variability; Genomes; Genotypes; Giardia; Glycoproteins; HIV; HIV Infections - epidemiology; HIV Infections - microbiology; Human immunodeficiency virus; Humans; Identification; Infant; Infant, Newborn; Kenya - epidemiology; Male; Medical research; Microscopy; Molecular Sequence Data; Pediatrics; Polymerase chain reaction; Polymorphism; Polymorphism, Restriction Fragment Length; Population genetics; Population studies; Protozoan Proteins - genetics; Public health; Restriction fragment length polymorphism; RNA, Protozoan - genetics; RNA, Ribosomal, 18S - genetics; Species; Studies; Urban Population; Varieties; Zoonoses; Kenya; South Africa; Nairobi Kenya

Globally Cryptosporidium and Giardia species are the most common non-bacterial causes of diarrhoea in children and HIV infected individuals, yet data on their role in paediatric diarrhoea in Kenya remains scant. This study investigated the occurrence of Cryptosporidium species, genotypes and subtype...