Ibuprofen Blunts Ventilatory Acclimatization to Sustained Hypoxia in Humans - Basaran, Kemal Erdem; Villongco, Michael; Ho, Baran; Ellis, Erika; Zarndt, Rachel; Antonova, Julie; Hopkins, Susan R.; Powell, Frank L. (PloS one, 2016)
Keywords: Acclimatization; Acclimatization - drug effects; Adolescent; Adult; Altitude; Altitude effects; Animal models; Anti-inflammatory agents; Anti-Inflammatory Agents, Non-Steroidal - adverse effects; Anti-Inflammatory Agents, Non-Steroidal - pharmacology; Brain stem; Breathing; Carotid body; Carotid Body - drug effects; Carotid Body - physiopathology; Chemoreceptor Cells - drug effects; Chemoreceptors; Chemoreceptors (internal); Chronic Disease; Cross-Over Studies; Dosage and administration; Double-Blind Method; Female; Gene expression; High altitude; High-altitude environments; Humans; Hypoventilation; Hypoxemia; Hypoxia; Hypoxia (Aquatic ecology); Hypoxia - physiopathology; Ibuprofen; Ibuprofen - adverse effects; Ibuprofen - pharmacology; Inflammation; Lung diseases; Male; Measurement methods; Medicine; Neural plasticity; Neuronal Plasticity - drug effects; Neuroplasticity; Nonsteroidal anti-inflammatory drugs; Oxygen - blood; Pain; Partial Pressure; Physiology; Respiration - drug effects; Respiratory Center - drug effects; Respiratory Center - physiopathology; Rodents; Sea level; Signaling; Ventilation; Ventilatory behavior; Young Adult