High Environmental Ozone Levels Lead to Enhanced Allergenicity of Birch Pollen

• Published in: PloS one Vol. 8; no. 11; p. e80147
• Main Authors: Beck, Isabelle, Jochner, Susanne, Gilles, Stefanie, McIntyre, Mareike, Buters, Jeroen T. M., Schmidt-Weber, Carsten, Behrendt, Heidrun, Ring, Johannes, Menzel, Annette, Traidl-Hoffmann, Claudia
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 20.11.2013; Public Library of Science (PLoS)
• Subjects: Air Pollutants - analysis; Air pollution; Allergenicity; Allergens; Allergens - immunology; Allergies; Allergy; Anthropogenic factors; Archives & records; Betula - immunology; Birch trees; Cell migration; Climate change; Dendritic cells; Dermatology; Dinoprostone - metabolism; Ecosystems; Education; Environmental factors; Enzyme-Linked Immunosorbent Assay; Future climates; Global temperature changes; Human influences; Humans; Immunology; In vivo methods and tests; Interleukin; Interleukin 12; Interleukins; Leukocyte migration; Leukotriene B4 - metabolism; Lipid composition; Lipids; Nitrogen dioxide; Ozone; Ozone - analysis; Pollen; Pollen - immunology; Pollution monitoring; Skin; Skin Tests; Studies; Temperature; Trends; Urban areas; Urbanization; Germany

Evidence is compelling for a positive correlation between climate change, urbanisation and prevalence of allergic sensitisation and diseases. The reason for this association is not clear to date. Some data point to a pro-allergenic effect of anthropogenic factors on susceptible individuals. To evalu...