How methodologic differences affect results of economic analyses: a systematic review of interferon gamma release assays for the diagnosis of LTBI

• Published in: PloS one Vol. 8; no. 3; p. e56044
• Main Authors: Oxlade, Olivia, Pinto, Marcia, Trajman, Anete, Menzies, Dick
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 07.03.2013; Public Library of Science (PLoS)
• Subjects: Analysis; Biological response modifiers; Cost analysis; Cost effectiveness; Cost-Benefit Analysis; Decision analysis; Decision Support Techniques; Economic analysis; Economic aspects; Epidemiology; Health aspects; Humans; Impact prediction; Infection; Infections; Interferon; Interferon gamma; Interferon-gamma Release Tests - economics; Interferon-gamma Release Tests - methods; Latent Tuberculosis - diagnosis; Latent Tuberculosis - economics; Latent Tuberculosis - epidemiology; Mass Screening - economics; Mass Screening - methods; Mathematical models; Medical diagnosis; Medicine; Models, Statistical; Quality; Quality Control; Quality-Adjusted Life Years; Reviews; Science Policy; Skin tests; Studies; Systematic review; Tuberculin; Tuberculin Test - economics; Tuberculin Test - methods; Tuberculosis; γ-Interferon; Brazil; Canada; Montreal Quebec Canada; Rio de Janeiro Brazil

Cost effectiveness analyses (CEA) can provide useful information on how to invest limited funds, however they are less useful if different analysis of the same intervention provide unclear or contradictory results. The objective of our study was to conduct a systematic review of methodologic aspects...