Hybrid spectral CT reconstruction

• Published in: PloS one Vol. 12; no. 7; p. e0180324
• Main Authors: Clark, Darin P., Badea, Cristian T.
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 06.07.2017; Public Library of Science (PLoS)
• Subjects: Animals; Barium; Barium - pharmacokinetics; Biology and Life Sciences; Calcium; Calcium - pharmacokinetics; Computed tomography; Computer and Information Sciences; Computer simulation; Contrast agents; Contrast Media - pharmacokinetics; Data acquisition; Decomposition; Detection equipment; Drug dosages; Energy; Energy resolution; Engineering and Technology; Feasibility studies; Health physics; High resolution; Iodine; Iodine - pharmacokinetics; Iterative methods; Medical imaging; Medicine and Health Sciences; Mice; Microscopy; Neural networks; Noise; Phantoms, Imaging; Photons; Physical Sciences; Physics; Point spread functions; Radiographic Image Interpretation, Computer-Assisted - methods; Rankings; Reconstruction; Research and Analysis Methods; Sarcoma; Sarcoma - diagnostic imaging; Sarcoma - pathology; Sensors; Separation; Simulation; Soft Tissue Neoplasms - diagnostic imaging; Soft Tissue Neoplasms - pathology; Spatial discrimination; Spatial resolution; Spectra; Tomography, X-Ray Computed - methods; X ray detectors; X-rays
• ISSN: 1932-6203; 1932-6203
• DOI: 10.1371/journal.pone.0180324

Current photon counting x-ray detector (PCD) technology faces limitations associated with spectral fidelity and photon starvation. One strategy for addressing these limitations is to supplement PCD data with high-resolution, low-noise data acquired with an energy-integrating detector (EID). In this...