Mu Opioid Receptor Binding Correlates with Nicotine Dependence and Reward in Smokers - Kuwabara, Hiroto; Heishman, Stephen J.; Brasic, James R.; Contoreggi, Carlo; Cascella, Nicola; Mackowick, Kristen M.; Taylor, Richard; Rousset, Olivier; Willis, William; Huestis, Marilyn A.; Concheiro, Marta; Wand, Gary; et al. (PloS one, 2014)
Keywords: Addictions; Adult; Alcohol; Binding; Biology and Life Sciences; Biomarkers - blood; Brain; Brain - diagnostic imaging; Brain - drug effects; Brain - metabolism; Brain research; Carbon Radioisotopes; Cigarette smoking; Cigarettes; Correlation analysis; Cortex (frontal); Cortex (temporal); Dopamine; Drug abuse; Drug addiction; Drug dependence; Endogenous opioids; Female; Fentanyl - analogs & derivatives; Human subjects; Humans; Male; Medical imaging; Metabolism; Middle Aged; Narcotics; Neuroimaging; Neurosciences; Nicotine; Nicotine - administration & dosage; Nicotine - blood; Nicotinic Agonists - administration & dosage; Nicotinic Agonists - blood; Opioid receptors (type mu); Positron emission; Positron emission tomography; Psychiatry; Psychopharmacology; Radiology; Radiopharmaceuticals; Receptors; Receptors, Opioid, mu - metabolism; Reinforcement; Reward; Science; Self Report; Severity of Illness Index; Smokers; Smoking; Smoking - metabolism; Smoking - psychology; Temporal lobe; Tobacco Use Disorder - diagnostic imaging; Tobacco Use Disorder - metabolism; Tobacco Use Disorder - psychology; Tomography; Young Adult; United States--US; Baltimore Maryland