Beyond Streptococcus mutans: Dental Caries Onset Linked to Multiple Species by 16S rRNA Community Analysis

• Published in: PloS one Vol. 7; no. 10; p. e47722
• Main Authors: Gross, Erin L., Beall, Clifford J., Kutsch, Stacey R., Firestone, Noah D., Leys, Eugene J., Griffen, Ann L.
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 16.10.2012; Public Library of Science (PLoS)
• Subjects: Acids; Analysis; Anesthesia; Bacteria; Bacteria - genetics; Bacteria - isolation & purification; Bacteriology; Biodiversity; Biofilms; Biology; Case-Control Studies; Causes of; Child, Preschool; Children; Cloning; Communities; Dental caries; Dental Caries - microbiology; Dentistry; Dentition; Development and progression; Disease; Disease prevention; Dominant species; Ecology; Enamel; Female; Fluorides; Gene sequencing; Health; Health aspects; Humans; Infant; Lactic acid; Male; Medicine; Microbiota; Microorganisms; Oral hygiene; Pathogenesis; Pediatrics; Phylogeny; Physiological aspects; Redundancy; Resilience; Restoration; RNA, Ribosomal, 16S - genetics; rRNA 16S; Species diversity; Streptococcus; Streptococcus gordonii; Streptococcus infections; Streptococcus mutans; Streptococcus mutans - classification; Streptococcus mutans - genetics; Streptococcus mutans - isolation & purification; Teeth; United States; United States > US; Ohio

Dental caries in very young children may be severe, result in serious infection, and require general anesthesia for treatment. Dental caries results from a shift within the biofilm community specific to the tooth surface, and acidogenic species are responsible for caries. Streptococcus mutans, the m...