Sera selected from national STI surveillance system shows Chlamydia trachomatis PgP3 antibody correlates with time since infection and number of previous infections

• Published in: PloS one Vol. 13; no. 12; p. e0208652
• Main Authors: Blomquist, Paula B, Mighelsen, Stephanie J, Wills, Gillian, McClure, Eleanor, Ades, Anthony E, Kounali, Daphne, Dunbar, J Kevin, McClure, Myra O, Soldan, Kate, Woodhall, Sarah C, Horner, Patrick
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 17.12.2018; Public Library of Science (PLoS)
• Subjects: Adolescent; Adult; Age; Analysis; Antibodies; Antibodies, Bacterial - blood; Antibodies, Bacterial - immunology; Antibody response; Antigens, Bacterial - immunology; Bacteria; Bacterial Proteins - immunology; Biology and Life Sciences; Chlamydia; Chlamydia infections; Chlamydia Infections - blood; Chlamydia Infections - diagnosis; Chlamydia Infections - epidemiology; Chlamydia Infections - immunology; Chlamydia trachomatis; Chlamydia trachomatis - immunology; Collaboration; Computed tomography; Condoms; Confidence intervals; Cross-Sectional Studies; Diagnosis; England; Enzyme-linked immunosorbent assay; Enzymes; Epidemiological Monitoring; Estimation; Female; Follow-Up Studies; Hepatitis; Humans; Hygiene; Immune response; Immunoglobulin G - blood; Incidence; Infections; Infectious diseases; Inflammatory diseases; Laboratories; Longitudinal Studies; Medical diagnosis; Medicine; Medicine and Health Sciences; People and places; Pneumonia; Population; Public health; Research and Analysis Methods; Sentinel surveillance; Seroepidemiologic Studies; Serologic tests; Serology; Sexually transmitted diseases; STD; Surveillance; Womens health; Young Adult; England; United Kingdom > UK

Seroprevalence surveys of Chlamydia trachomatis (CT) antibodies are promising for estimating age-specific CT cumulative incidence, however accurate estimates require improved understanding of antibody response to CT infection. We used GUMCAD, England's national sexually transmitted infection (S...