Evaluating trajectories of episodic memory in normal cognition and mild cognitive impairment: Results from ADNI

• Published in: PloS one Vol. 14; no. 2; p. e0212435
• Main Authors: Ding, Xiuhua, Charnigo, Richard J., Schmitt, Frederick A., Kryscio, Richard J., Abner, Erin L.
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 25.02.2019; Public Library of Science (PLoS)
• Subjects: Age; Aged; Aged, 80 and over; Aging; Alzheimer Disease - diagnosis; Alzheimer Disease - psychology; Alzheimer's disease; Apolipoprotein E; Apolipoprotein E4; Apolipoproteins; Auditory discrimination learning; Biology and Life Sciences; Biomarkers; Care and treatment; Cognition; Cognition & reasoning; Cognitive ability; Cognitive disorders; Cognitive Dysfunction - diagnosis; Cognitive Dysfunction - psychology; Data processing; Dementia; Dementia disorders; Diagnosis; Diagnostic systems; Disease Progression; Episodic memory; Female; Humans; Impairment; Intelligence tests; Longitudinal Studies; Male; Medical imaging; Medicine and Health Sciences; Memory; Memory and Learning Tests; Memory, Episodic; Middle Aged; Models, Psychological; Models, Statistical; Neuroimaging; Neurology; Older people; Physiological aspects; Population; Prognosis; Risk analysis; Risk Factors; Shape memory; Social Sciences; Studies; Trajectory analysis; Verbal learning; United States; United States > US; Kentucky

Memory assessment is a key factor for the diagnosis of cognitive impairment. However, memory performance over time may be quite heterogeneous within diagnostic groups. To identify latent trajectories in memory performance and their associated risk factors, we analyzed data from Alzheimer's Dise...