A calming hug: Design and validation of a tactile aid to ease anxiety

Anxiety disorders affect approximately one third of people during their lifetimes and are the ninth leading cause of global disability. Current treatments focus on therapy and pharmacological interventions. However, therapy is costly and pharmacological interventions often have undesirable side-effe...

Full description

Saved in:
Bibliographic Details
Published inPloS one Vol. 17; no. 3; p. e0259838
Main Authors Haynes, Alice C, Lywood, Annie, Crowe, Emily M, Fielding, Jessica L, Rossiter, Jonathan M, Kent, Christopher
Format Journal Article
LanguageEnglish
Published United States Public Library of Science 09.03.2022
Public Library of Science (PLoS)
Subjects
Online AccessGet full text

Cover

Loading…
Abstract Anxiety disorders affect approximately one third of people during their lifetimes and are the ninth leading cause of global disability. Current treatments focus on therapy and pharmacological interventions. However, therapy is costly and pharmacological interventions often have undesirable side-effects. Healthy people also regularly suffer periods of anxiety. Therefore, a non-pharmacological, intuitive, home intervention would be complementary to other treatments and beneficial for non-clinical groups. Existing at-home anxiety aids, such as guided meditations, typically employ visual and/or audio stimuli to guide the user into a calmer state. However, the tactile sense has the potential to be a more natural modality to target in an anxiety-calming device. The tactile domain is relatively under-explored, but we suggest that there are manifold physiological and affective qualities of touch that lend it to the task. In this study we demonstrate that haptic technology can offer an enjoyable, effective and widely accessible alternative for easing state anxiety. We describe a novel huggable haptic interface that pneumatically simulates slow breathing. We discuss the development of this interface through a focus group evaluating five prototypes with embedded behaviours ('breathing', 'purring', 'heartbeat' and 'illumination'). Ratings indicated that the 'breathing' prototype was most pleasant to interact with and participants described this prototype as 'calming' and 'soothing', reminding them of a person breathing. This prototype was developed into an ergonomic huggable cushion containing a pneumatic chamber powered by an external pump allowing the cushion to 'breathe'. A mixed-design experiment (n = 129) inducing anxiety through a group mathematics test found that the device was effective at reducing pre-test anxiety compared to a control (no intervention) condition and that this reduction in anxiety was indistinguishable from that of a guided meditation. Our findings highlight the efficacy of this interface, demonstrating that haptic technologies can be effective at easing anxiety. We suggest that the field should be explored in more depth to capture the nuances of different modalities in relation to specific situations and trait characteristics.
AbstractList Anxiety disorders affect approximately one third of people during their lifetimes and are the ninth leading cause of global disability. Current treatments focus on therapy and pharmacological interventions. However, therapy is costly and pharmacological interventions often have undesirable side-effects. Healthy people also regularly suffer periods of anxiety. Therefore, a non-pharmacological, intuitive, home intervention would be complementary to other treatments and beneficial for non-clinical groups. Existing at-home anxiety aids, such as guided meditations, typically employ visual and/or audio stimuli to guide the user into a calmer state. However, the tactile sense has the potential to be a more natural modality to target in an anxiety-calming device. The tactile domain is relatively under-explored, but we suggest that there are manifold physiological and affective qualities of touch that lend it to the task. In this study we demonstrate that haptic technology can offer an enjoyable, effective and widely accessible alternative for easing state anxiety. We describe a novel huggable haptic interface that pneumatically simulates slow breathing. We discuss the development of this interface through a focus group evaluating five prototypes with embedded behaviours (‘breathing’, ‘purring’, ‘heartbeat’ and ‘illumination’). Ratings indicated that the ‘breathing’ prototype was most pleasant to interact with and participants described this prototype as ‘calming’ and ‘soothing’, reminding them of a person breathing. This prototype was developed into an ergonomic huggable cushion containing a pneumatic chamber powered by an external pump allowing the cushion to ‘breathe’. A mixed-design experiment (n = 129) inducing anxiety through a group mathematics test found that the device was effective at reducing pre-test anxiety compared to a control (no intervention) condition and that this reduction in anxiety was indistinguishable from that of a guided meditation. Our findings highlight the efficacy of this interface, demonstrating that haptic technologies can be effective at easing anxiety. We suggest that the field should be explored in more depth to capture the nuances of different modalities in relation to specific situations and trait characteristics.
Audience Academic
Author Haynes, Alice C
Rossiter, Jonathan M
Crowe, Emily M
Lywood, Annie
Fielding, Jessica L
Kent, Christopher
AuthorAffiliation 5 School of Psychological Science, University of Bristol, Bristol, United Kingdom
University of Pennsylvania Perelman School of Medicine, UNITED STATES
2 Soft Robotics Group, Bristol Robotics Laboratory, Bristol, United Kingdom
4 Faculty of Behavioural and Movement Sciences, Vrije Universiteit, Amsterdam, Netherlands
1 Engineering Mathematics Department, University of Bristol, Bristol, United Kingdom
3 Bonnie Binary Ltd, Bristol, United Kingdom
AuthorAffiliation_xml – name: University of Pennsylvania Perelman School of Medicine, UNITED STATES
– name: 3 Bonnie Binary Ltd, Bristol, United Kingdom
– name: 5 School of Psychological Science, University of Bristol, Bristol, United Kingdom
– name: 4 Faculty of Behavioural and Movement Sciences, Vrije Universiteit, Amsterdam, Netherlands
– name: 2 Soft Robotics Group, Bristol Robotics Laboratory, Bristol, United Kingdom
– name: 1 Engineering Mathematics Department, University of Bristol, Bristol, United Kingdom
Author_xml – sequence: 1
  givenname: Alice C
  orcidid: 0000-0003-2146-6902
  surname: Haynes
  fullname: Haynes, Alice C
  organization: Soft Robotics Group, Bristol Robotics Laboratory, Bristol, United Kingdom
– sequence: 2
  givenname: Annie
  surname: Lywood
  fullname: Lywood, Annie
  organization: Bonnie Binary Ltd, Bristol, United Kingdom
– sequence: 3
  givenname: Emily M
  orcidid: 0000-0001-8265-7791
  surname: Crowe
  fullname: Crowe, Emily M
  organization: Faculty of Behavioural and Movement Sciences, Vrije Universiteit, Amsterdam, Netherlands
– sequence: 4
  givenname: Jessica L
  orcidid: 0000-0002-0950-4788
  surname: Fielding
  fullname: Fielding, Jessica L
  organization: School of Psychological Science, University of Bristol, Bristol, United Kingdom
– sequence: 5
  givenname: Jonathan M
  surname: Rossiter
  fullname: Rossiter, Jonathan M
  organization: Soft Robotics Group, Bristol Robotics Laboratory, Bristol, United Kingdom
– sequence: 6
  givenname: Christopher
  surname: Kent
  fullname: Kent, Christopher
  organization: School of Psychological Science, University of Bristol, Bristol, United Kingdom
BackLink https://www.ncbi.nlm.nih.gov/pubmed/35263344$$D View this record in MEDLINE/PubMed
BookMark eNqNkk1r3DAQhk1JaZJt_0FpDYXSHnYrS7Jk9VBY0rRdCAT6dRWyPrwKWmlrySH599VmnbAuORQdNMjPvOOZeU-LIx-8LoqXFVhUiFYfrsLQe-EW2_y8ALBmDWqeFCcVQ3BOIEBHB_FxcRrjFQA1agh5VhyjGhKEMD4pzpelFG5jfVeuh-5j-VlH2_lSeFVeC2eVSDb4MphSlEnIZJ0uhVVlCqUWMcf-xup0-7x4aoSL-sV4z4pfX85_nn2bX1x-XZ0tL-aSMJjmuazWNWUSEAxqUqscCIVNAzEGjMqaYIhUZaiRwhjQ4hYwhElLjYasIRjNitd73a0LkY8TiDw3Q2sKIa0ysdoTKogrvu3tRvS3PAjL7x5C33HRJyud5lhRVrdUNMAwLFnTNMa0CtWsxqpFFc1an8ZqQ7vRSmqfeuEmotMv3q55F655wwAhuM4C70aBPvwZdEx8Y6PUzgmvw3D33w2oEKQso2_-QR_vbqQ6kRuw3oRcV-5E-ZIwAmFF8l5nxeIRKh-lN1Zmu5i8xmnC-0lCZpK-SZ0YYuSrH9__n738PWXfHrBrLVxax-CGnafiFMR7UPYhxl6bhyFXgO_cfj8NvnM7H92e014dLugh6d7e6C-VmPjN
CitedBy_id crossref_primary_10_1007_s12369_023_01037_6
crossref_primary_10_1145_3610099
crossref_primary_10_3390_electronics12163479
crossref_primary_10_1038_s41562_024_01841_8
crossref_primary_10_1080_17439760_2023_2170273
crossref_primary_10_1371_journal_pone_0285002
crossref_primary_10_1145_3648615
crossref_primary_10_20517_ss_2023_52
crossref_primary_10_3389_fphys_2024_1393497
crossref_primary_10_1109_LRA_2023_3262177
Cites_doi 10.1016/j.jad.2012.11.026
10.1145/2971648.2971752
10.14302/issn.2576-6694.jbbs-18-1887
10.31887/DCNS.2015.17.3/bbandelow
10.1145/3357236.3395532
10.1016/j.ctcp.2014.07.002
10.1007/978-3-319-57987-0_39
10.3389/fnhum.2018.00353
10.1007/978-3-319-21383-5_75
10.3389/fpsyg.2018.01192
10.1371/journal.pone.0164822
10.1007/978-3-030-34230-2_6
10.1145/2839462.2839480
10.1145/3313831.3376757
10.1016/j.tvjl.2018.02.014
10.3389/fpsyt.2020.555058
10.1038/srep03034
10.1145/3374920.3374938
10.1080/10253890601029751
10.1016/j.neubiorev.2008.09.011
10.1159/000119004
10.1371/journal.pone.0146131
10.1111/j.2044-8279.2012.02081.x
10.1016/j.physbeh.2017.05.006
10.1080/00207450590956459
10.1016/S0034-5687(87)80018-X
10.1371/journal.pone.0171220
10.1155/2018/3281040
10.1145/3334480.3382938
10.1016/j.biopsycho.2017.07.007
10.3928/00989134-20150806-44
10.1016/j.mehy.2006.02.042
10.1038/s41598-019-56204-5
10.1111/ajag.12099
10.1371/journal.pone.0173457
10.1080/24735132.2019.1593295
10.1038/s41598-017-02274-2
10.2752/175303712X13316289505468
10.4187/respcare.01655
10.1080/10705500802222972
10.1145/2851581.2892452
10.1097/PSY.0b013e318187aef7
10.36227/techrxiv.14601192.v1
10.1016/j.paid.2005.11.025
10.1037/0022-0663.97.2.268
10.3389/fpsyg.2015.01986
10.1109/TOH.2015.2396896
10.1016/j.cpr.2008.02.008
10.1007/s40750-016-0052-x
10.1089/acm.2010.0007
10.1121/1.4777098
10.1111/ppc.12184
10.1097/01.psy.0000170341.88395.47
10.1111/j.2044-8260.1992.tb00997.x
10.1016/j.biopsycho.2004.11.002
10.3109/10641963.2010.531850
10.1016/j.jmbbm.2016.03.001
10.1080/08964280309596065
10.1145/2971485.2996727
10.1145/3191760
10.1145/3170427.3188616
10.1016/j.isci.2020.100996
10.2752/175303712X13240472427311
10.1109/JBHI.2014.2349153
10.1002/9780470479216.corpsy0943
10.1145/3275476.3275492
10.1016/j.autneu.2010.06.011
10.1016/j.mehy.2012.01.021
10.1016/0031-9384(94)90315-8
10.1152/jappl.1994.77.3.1548
10.1183/20734735.009817
10.1145/1979742.1979831
10.1037/0022-3514.85.2.348
10.3233/JAD-160703
10.3389/fpsyg.2016.00537
10.1109/EMBC44109.2020.9175900
10.1145/3290605.3300687
10.7551/mitpress/9959.001.0001
10.1007/s12671-019-01178-8
10.1109/TAFFC.2015.2457893
10.1155/2013/743504
10.3389/fpsyg.2017.00874
10.1016/j.biopsycho.2015.04.001
ContentType Journal Article
Copyright COPYRIGHT 2022 Public Library of Science
2022 Haynes et al. This is an open access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.
2022 Haynes et al 2022 Haynes et al
Copyright_xml – notice: COPYRIGHT 2022 Public Library of Science
– notice: 2022 Haynes et al. This is an open access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.
– notice: 2022 Haynes et al 2022 Haynes et al
DBID CGR
CUY
CVF
ECM
EIF
NPM
AAYXX
CITATION
IOV
ISR
3V.
7QG
7QL
7QO
7RV
7SN
7SS
7T5
7TG
7TM
7U9
7X2
7X7
7XB
88E
8AO
8C1
8FD
8FE
8FG
8FH
8FI
8FJ
8FK
ABJCF
ABUWG
AFKRA
ARAPS
ATCPS
AZQEC
BBNVY
BENPR
BGLVJ
BHPHI
C1K
CCPQU
D1I
DWQXO
FR3
FYUFA
GHDGH
GNUQQ
H94
HCIFZ
K9.
KB.
KB0
KL.
L6V
LK8
M0K
M0S
M1P
M7N
M7P
M7S
NAPCQ
P5Z
P62
P64
PATMY
PDBOC
PIMPY
PQEST
PQQKQ
PQUKI
PRINS
PTHSS
PYCSY
RC3
7X8
5PM
DOA
DOI 10.1371/journal.pone.0259838
DatabaseName Medline
MEDLINE
MEDLINE (Ovid)
MEDLINE
MEDLINE
PubMed
CrossRef
Gale In Context: Opposing Viewpoints
Gale In Context: Science
ProQuest Central (Corporate)
Animal Behavior Abstracts
Bacteriology Abstracts (Microbiology B)
Biotechnology Research Abstracts
Proquest Nursing & Allied Health Source
Ecology Abstracts
Entomology Abstracts (Full archive)
Immunology Abstracts
Meteorological & Geoastrophysical Abstracts
Nucleic Acids Abstracts
Virology and AIDS Abstracts
Agricultural Science Collection
ProQuest - Health & Medical Complete保健、医学与药学数据库
ProQuest Central (purchase pre-March 2016)
Medical Database (Alumni Edition)
ProQuest Pharma Collection
ProQuest Public Health Database
Technology Research Database
ProQuest SciTech Collection
ProQuest Technology Collection
ProQuest Natural Science Collection
Hospital Premium Collection
Hospital Premium Collection (Alumni Edition)
ProQuest Central (Alumni) (purchase pre-March 2016)
Materials Science & Engineering Collection
ProQuest Central (Alumni)
ProQuest Central
Advanced Technologies & Aerospace Database‎ (1962 - current)
Agricultural & Environmental Science Collection
ProQuest Central Essentials
Biological Science Collection
ProQuest Central
Technology Collection
ProQuest Natural Science Collection
Environmental Sciences and Pollution Management
ProQuest One Community College
ProQuest Materials Science Collection
ProQuest Central
Engineering Research Database
Health Research Premium Collection
Health Research Premium Collection (Alumni)
ProQuest Central Student
AIDS and Cancer Research Abstracts
SciTech Premium Collection
ProQuest Health & Medical Complete (Alumni)
Materials Science Database
Nursing & Allied Health Database (Alumni Edition)
Meteorological & Geoastrophysical Abstracts - Academic
ProQuest Engineering Collection
Biological Sciences
Agriculture Science Database
Health & Medical Collection (Alumni Edition)
PML(ProQuest Medical Library)
Algology Mycology and Protozoology Abstracts (Microbiology C)
Biological Science Database
Engineering Database
Nursing & Allied Health Premium
Advanced Technologies & Aerospace Database
ProQuest Advanced Technologies & Aerospace Collection
Biotechnology and BioEngineering Abstracts
Environmental Science Database
Materials Science Collection
ProQuest Publicly Available Content database
ProQuest One Academic Eastern Edition (DO NOT USE)
ProQuest One Academic
ProQuest One Academic UKI Edition
ProQuest Central China
Engineering Collection
Environmental Science Collection
Genetics Abstracts
MEDLINE - Academic
PubMed Central (Full Participant titles)
DOAJ Directory of Open Access Journals
DatabaseTitle MEDLINE
Medline Complete
MEDLINE with Full Text
PubMed
MEDLINE (Ovid)
CrossRef
Agricultural Science Database
Publicly Available Content Database
ProQuest Central Student
ProQuest Advanced Technologies & Aerospace Collection
ProQuest Central Essentials
Nucleic Acids Abstracts
SciTech Premium Collection
ProQuest Central China
Environmental Sciences and Pollution Management
Health Research Premium Collection
Meteorological & Geoastrophysical Abstracts
Natural Science Collection
Biological Science Collection
ProQuest Medical Library (Alumni)
Engineering Collection
Advanced Technologies & Aerospace Collection
Engineering Database
Virology and AIDS Abstracts
ProQuest Biological Science Collection
ProQuest One Academic Eastern Edition
Agricultural Science Collection
ProQuest Hospital Collection
ProQuest Technology Collection
Health Research Premium Collection (Alumni)
Biological Science Database
Ecology Abstracts
ProQuest Hospital Collection (Alumni)
Biotechnology and BioEngineering Abstracts
Environmental Science Collection
Entomology Abstracts
Nursing & Allied Health Premium
ProQuest Health & Medical Complete
ProQuest One Academic UKI Edition
Environmental Science Database
ProQuest Nursing & Allied Health Source (Alumni)
Engineering Research Database
ProQuest One Academic
Meteorological & Geoastrophysical Abstracts - Academic
Technology Collection
Technology Research Database
Materials Science Collection
ProQuest Health & Medical Complete (Alumni)
ProQuest Central (Alumni Edition)
ProQuest One Community College
ProQuest Natural Science Collection
ProQuest Pharma Collection
ProQuest Central
Genetics Abstracts
ProQuest Engineering Collection
Biotechnology Research Abstracts
Health and Medicine Complete (Alumni Edition)
ProQuest Central Korea
Bacteriology Abstracts (Microbiology B)
Algology Mycology and Protozoology Abstracts (Microbiology C)
Agricultural & Environmental Science Collection
AIDS and Cancer Research Abstracts
Materials Science Database
ProQuest Materials Science Collection
ProQuest Public Health
ProQuest Nursing & Allied Health Source
ProQuest SciTech Collection
Advanced Technologies & Aerospace Database
ProQuest Medical Library
Animal Behavior Abstracts
Materials Science & Engineering Collection
Immunology Abstracts
ProQuest Central (Alumni)
MEDLINE - Academic
DatabaseTitleList
Agricultural Science Database


CrossRef
MEDLINE


Database_xml – sequence: 1
  dbid: DOA
  name: DOAJ Directory of Open Access Journals
  url: https://www.doaj.org/
  sourceTypes: Open Website
– sequence: 2
  dbid: NPM
  name: PubMed
  url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed
  sourceTypes: Index Database
– sequence: 3
  dbid: EIF
  name: MEDLINE
  url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search
  sourceTypes: Index Database
– sequence: 4
  dbid: 8FG
  name: ProQuest Technology Collection
  url: https://search.proquest.com/technologycollection1
  sourceTypes: Aggregation Database
DeliveryMethod fulltext_linktorsrc
Discipline Sciences (General)
Mathematics
DocumentTitleAlternate Design and validation of a tactile aid to ease anxiety
EISSN 1932-6203
Editor Oathes, Desmond J.
Editor_xml – sequence: 1
  givenname: Desmond J.
  surname: Oathes
  fullname: Oathes, Desmond J.
EndPage e0259838
ExternalDocumentID 2637572271
oai_doaj_org_article_4d795b7a80f94c9888ffbd35954db317
A696221663
10_1371_journal_pone_0259838
35263344
Genre Research Support, Non-U.S. Gov't
Journal Article
GeographicLocations United Kingdom
United Kingdom--UK
GeographicLocations_xml – name: United Kingdom
– name: United Kingdom--UK
GrantInformation_xml – fundername: ;
  grantid: EP/T020792/1
– fundername: ;
  grantid: Seedcorn
– fundername: ;
  grantid: EP/R02961X/1
– fundername: ;
  grantid: EP/M020460/1
– fundername: ;
  grantid: EP/S026096/1
– fundername: ;
  grantid: EP/N509619/1
GroupedDBID ---
123
29O
2WC
3V.
53G
5VS
7RV
7X2
7X7
7XC
88E
8AO
8C1
8CJ
8FE
8FG
8FH
8FI
8FJ
A8Z
AAFWJ
ABDBF
ABIVO
ABJCF
ABUWG
ACGFO
ACIHN
ACIWK
ACPRK
ADBBV
ADRAZ
AEAQA
AENEX
AFKRA
AFPKN
AFRAH
AHMBA
ALIPV
ALMA_UNASSIGNED_HOLDINGS
AOIJS
APEBS
ARAPS
ATCPS
BAWUL
BBNVY
BBORY
BCNDV
BENPR
BGLVJ
BHPHI
BKEYQ
BPHCQ
BVXVI
BWKFM
CCPQU
CGR
CS3
CUY
CVF
D1I
D1J
D1K
DIK
DU5
E3Z
EAP
EAS
EBD
ECM
EIF
EMOBN
ESTFP
ESX
EX3
F5P
FPL
FYUFA
GROUPED_DOAJ
GX1
HCIFZ
HH5
HMCUK
HYE
IAO
IEA
IHR
IHW
INH
INR
IOV
IPNFZ
IPY
ISE
ISR
ITC
K6-
KB.
KQ8
L6V
LK5
LK8
M0K
M1P
M48
M7P
M7R
M7S
M~E
NAPCQ
NPM
O5R
O5S
OK1
P2P
P62
PATMY
PDBOC
PIMPY
PQQKQ
PROAC
PSQYO
PTHSS
PV9
PYCSY
RIG
RNS
RPM
RZL
SV3
TR2
UKHRP
WOQ
WOW
~02
~KM
AAYXX
CITATION
7QG
7QL
7QO
7SN
7SS
7T5
7TG
7TM
7U9
7XB
8FD
8FK
AZQEC
C1K
DWQXO
FR3
GNUQQ
H94
K9.
KL.
M7N
P64
PQEST
PQUKI
PRINS
RC3
7X8
5PM
-
02
AAPBV
ABPTK
ADACO
BBAFP
KM
ID FETCH-LOGICAL-c692t-352ee579c0640565dc06ad4f8244097c56423d1f7fcaff0b4b09346b7fe298643
IEDL.DBID RPM
ISSN 1932-6203
IngestDate Sun Apr 03 16:01:27 EDT 2022
Fri Jul 05 11:31:00 EDT 2024
Tue Sep 17 21:26:01 EDT 2024
Wed Jul 24 18:57:47 EDT 2024
Fri Sep 13 05:41:36 EDT 2024
Thu Feb 22 23:23:22 EST 2024
Fri Feb 02 04:03:39 EST 2024
Thu Aug 01 19:54:54 EDT 2024
Thu Aug 01 20:28:08 EDT 2024
Tue Aug 20 22:05:06 EDT 2024
Fri Aug 23 02:06:21 EDT 2024
Sat Sep 28 08:20:58 EDT 2024
IsDoiOpenAccess true
IsOpenAccess true
IsPeerReviewed true
IsScholarly true
Issue 3
Language English
License This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Creative Commons Attribution License
LinkModel DirectLink
MergedId FETCHMERGED-LOGICAL-c692t-352ee579c0640565dc06ad4f8244097c56423d1f7fcaff0b4b09346b7fe298643
Notes ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
Competing Interests: The commercial affiliation with Bonnie Binary does not alter our adherence to PLOS ONE policies on sharing data and materials. There are no patents, products in development or marketed products associated with this research to declare.
ACH, JMR and CK are primary authors of this work. ACH, AL and JMR authors developed the prototypes and hardware for this study. JLF and CK authors were primary supervisors for the experiment in this study.
ORCID 0000-0003-2146-6902
0000-0001-8265-7791
0000-0002-0950-4788
OpenAccessLink https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8906645/
PMID 35263344
PQID 2637572271
PQPubID 1436336
PageCount e0259838
ParticipantIDs plos_journals_2637572271
doaj_primary_oai_doaj_org_article_4d795b7a80f94c9888ffbd35954db317
pubmedcentral_primary_oai_pubmedcentral_nih_gov_8906645
proquest_miscellaneous_2638013279
proquest_journals_2637572271
gale_infotracmisc_A696221663
gale_infotracacademiconefile_A696221663
gale_incontextgauss_ISR_A696221663
gale_incontextgauss_IOV_A696221663
gale_healthsolutions_A696221663
crossref_primary_10_1371_journal_pone_0259838
pubmed_primary_35263344
PublicationCentury 2000
PublicationDate 20220309
PublicationDateYYYYMMDD 2022-03-09
PublicationDate_xml – month: 3
  year: 2022
  text: 20220309
  day: 9
PublicationDecade 2020
PublicationPlace United States
PublicationPlace_xml – name: United States
– name: San Francisco
– name: San Francisco, CA USA
PublicationTitle PloS one
PublicationTitleAlternate PLoS One
PublicationYear 2022
Publisher Public Library of Science
Public Library of Science (PLoS)
Publisher_xml – name: Public Library of Science
– name: Public Library of Science (PLoS)
References C Regehr (pone.0259838.ref003) 2013; 148
C Triscoli (pone.0259838.ref014) 2017; 128
T Field (pone.0259838.ref011) 2005; 115
MA Russo (pone.0259838.ref058) 2017; 13
R Martos-Montes (pone.0259838.ref026) 2019; 8
S Yoshida (pone.0259838.ref037) 2020
S Keshmiri (pone.0259838.ref051) 2018; 9
YF Chen (pone.0259838.ref059) 2017; 53
A Suga (pone.0259838.ref041) 2019; 9
W Chen (pone.0259838.ref044) 2014; 19
H Olausson (pone.0259838.ref036) 2010; 34
KE Barrett (pone.0259838.ref081) 2019
H Mason (pone.0259838.ref082) 2013; 2013
pone.0259838.ref027
D Macher (pone.0259838.ref008) 2013; 83
KM Grewen (pone.0259838.ref013) 2005; 67
C Gustafsson (pone.0259838.ref032) 2015; 41
I Morrison (pone.0259838.ref016) 2016; 2
MS Chapell (pone.0259838.ref007) 2005; 97
TG Sato (pone.0259838.ref067) 2015; 8
TM Marteau (pone.0259838.ref091) 1992; 31
E Dijkstra (pone.0259838.ref078) 2018; 234
RT Azevedo (pone.0259838.ref019) 2017; 7
A Serin (pone.0259838.ref020) 2018; 1
H Walach (pone.0259838.ref093) 2006; 40
L Lindgren (pone.0259838.ref015) 2010; 158
H Kaneko (pone.0259838.ref085) 2012; 57
KM Grewen (pone.0259838.ref039) 2003; 29
M Eckstein (pone.0259838.ref024) 2020; 11
DA Dimitriev (pone.0259838.ref005) 2016; 11
H Cho (pone.0259838.ref061) 2016; 11
X Ma (pone.0259838.ref080) 2017; 8
KS Cheng (pone.0259838.ref096) 2019; 10
BW Smith (pone.0259838.ref092) 2008; 15
pone.0259838.ref048
pone.0259838.ref047
J Holt-Lunstad (pone.0259838.ref010) 2008; 70
pone.0259838.ref046
S Shea (pone.0259838.ref084) 1987; 68
MP Sammon (pone.0259838.ref043) 1994; 77
YS Sefidgar (pone.0259838.ref023) 2015; 7
K NAz (pone.0259838.ref083) 2004; 38
P Kolisko (pone.0259838.ref055) 2004; 34
T McDaniel (pone.0259838.ref073) 2020
N Weekes (pone.0259838.ref004) 2006; 9
C Streeter (pone.0259838.ref053) 2012; 78
pone.0259838.ref077
pone.0259838.ref074
KC Light (pone.0259838.ref038) 2005; 69
pone.0259838.ref076
pone.0259838.ref075
PE Paredes (pone.0259838.ref069) 2018; 2
pone.0259838.ref070
GK Pal (pone.0259838.ref060) 2004; 120
pone.0259838.ref072
pone.0259838.ref071
Z Zhang (pone.0259838.ref006) 2011; 33
R Pawling (pone.0259838.ref034) 2017; 12
PJ Seignourel (pone.0259838.ref099) 2008; 28
R Jerath (pone.0259838.ref056) 2006; 67
T Field (pone.0259838.ref040) 2014; 20
D Tran (pone.0259838.ref086) 2016; 60
WA Lu (pone.0259838.ref054) 2011; 17
M Van Puyvelde (pone.0259838.ref042) 2015; 108
pone.0259838.ref066
E von Muggenthaler (pone.0259838.ref030) 2001; 110
pone.0259838.ref068
pone.0259838.ref063
pone.0259838.ref062
pone.0259838.ref065
pone.0259838.ref064
H Sumioka (pone.0259838.ref049) 2013; 3
C Triscoli (pone.0259838.ref012) 2017; 177
L Handlin (pone.0259838.ref029) 2012; 25
R Yamazaki (pone.0259838.ref050) 2016; 7
DM Ellingsen (pone.0259838.ref025) 2016; 6
pone.0259838.ref018
pone.0259838.ref017
A Sugawara (pone.0259838.ref028) 2012; 25
RD Morey (pone.0259838.ref079) 2008; 4
CC Streeter (pone.0259838.ref052) 2010; 16
pone.0259838.ref098
pone.0259838.ref097
pone.0259838.ref094
X Zhang (pone.0259838.ref033) 2018; 2018
H Hahn (pone.0259838.ref009) 2017; 12
H Robinson (pone.0259838.ref022) 2015; 34
pone.0259838.ref090
EW Ingersoll (pone.0259838.ref045) 1994; 56
C Treadaway (pone.0259838.ref021) 2019; 3
A Zaccaro (pone.0259838.ref057) 2018; 12
JJ Gross (pone.0259838.ref095) 2003; 85
pone.0259838.ref088
pone.0259838.ref002
S Petersen (pone.0259838.ref031) 2017; 55
pone.0259838.ref087
C Kirschbaum (pone.0259838.ref089) 1993; 28
P Taneja (pone.0259838.ref035) 2019
B Bandelow (pone.0259838.ref001) 2015; 17
References_xml – volume: 148
  start-page: 1
  issue: 1
  year: 2013
  ident: pone.0259838.ref003
  article-title: Interventions to reduce stress in university students: A review and meta-analysis
  publication-title: Journal of affective disorders
  doi: 10.1016/j.jad.2012.11.026
  contributor:
    fullname: C Regehr
– ident: pone.0259838.ref047
  doi: 10.1145/2971648.2971752
– volume: 1
  start-page: 42
  issue: 2
  year: 2018
  ident: pone.0259838.ref020
  article-title: The Therapeutic Effect of Bilateral Alternating Stimulation Tactile Form Technology on the Stress Response
  publication-title: Journal of Biotechnology and Biomedical Science
  doi: 10.14302/issn.2576-6694.jbbs-18-1887
  contributor:
    fullname: A Serin
– volume: 17
  start-page: 327
  issue: 3
  year: 2015
  ident: pone.0259838.ref001
  article-title: Epidemiology of anxiety disorders in the 21st century
  publication-title: Dialogues in clinical neuroscience
  doi: 10.31887/DCNS.2015.17.3/bbandelow
  contributor:
    fullname: B Bandelow
– volume: 38
  start-page: 396
  issue: 3
  year: 2004
  ident: pone.0259838.ref083
  article-title: Relationship between color and emotion: A study of college students
  publication-title: College Student J
  contributor:
    fullname: K NAz
– ident: pone.0259838.ref048
  doi: 10.1145/3357236.3395532
– volume: 20
  start-page: 224
  issue: 4
  year: 2014
  ident: pone.0259838.ref040
  article-title: Massage therapy research review
  publication-title: Complementary therapies in clinical practice
  doi: 10.1016/j.ctcp.2014.07.002
  contributor:
    fullname: T Field
– ident: pone.0259838.ref074
  doi: 10.1007/978-3-319-57987-0_39
– volume: 12
  start-page: 353
  year: 2018
  ident: pone.0259838.ref057
  article-title: How breath-control can change your life: a systematic review on psycho-physiological correlates of slow breathing
  publication-title: Frontiers in human neuroscience
  doi: 10.3389/fnhum.2018.00353
  contributor:
    fullname: A Zaccaro
– volume: 17
  start-page: 8
  issue: 4
  year: 2011
  ident: pone.0259838.ref054
  article-title: Foot reflexology can increase vagal modulation, decrease sympathetic modulation, and lower blood pressure in healthy subjects and patients with coronary artery disease
  publication-title: Alternative therapies in health and medicine
  contributor:
    fullname: WA Lu
– ident: pone.0259838.ref070
  doi: 10.1007/978-3-319-21383-5_75
– volume: 9
  start-page: 1192
  year: 2018
  ident: pone.0259838.ref051
  article-title: Bodily-contact communication medium induces relaxed mode of brain activity while increasing its dynamical complexity: a pilot study
  publication-title: Frontiers in psychology
  doi: 10.3389/fpsyg.2018.01192
  contributor:
    fullname: S Keshmiri
– volume: 11
  start-page: e0164822
  issue: 10
  year: 2016
  ident: pone.0259838.ref061
  article-title: The effectiveness of daily mindful breathing practices on test anxiety of students
  publication-title: PloS one
  doi: 10.1371/journal.pone.0164822
  contributor:
    fullname: H Cho
– start-page: 149
  volume-title: Haptic Interfaces for Accessibility, Health, and Enhanced Quality of Life
  year: 2020
  ident: pone.0259838.ref073
  doi: 10.1007/978-3-030-34230-2_6
  contributor:
    fullname: T McDaniel
– ident: pone.0259838.ref065
  doi: 10.1145/2839462.2839480
– ident: pone.0259838.ref068
  doi: 10.1145/3313831.3376757
– volume: 234
  start-page: 96
  year: 2018
  ident: pone.0259838.ref078
  article-title: Respiratory rate of clinically healthy cats measured in veterinary consultation rooms
  publication-title: The Veterinary Journal
  doi: 10.1016/j.tvjl.2018.02.014
  contributor:
    fullname: E Dijkstra
– volume: 11
  year: 2020
  ident: pone.0259838.ref024
  article-title: Calming Effects of Touch in Human, Animal, and Robotic Interaction—Scientific State-of-the-Art and Technical Advances
  publication-title: Frontiers in psychiatry
  doi: 10.3389/fpsyt.2020.555058
  contributor:
    fullname: M Eckstein
– volume: 3
  start-page: 1
  issue: 1
  year: 2013
  ident: pone.0259838.ref049
  article-title: Huggable communication medium decreases cortisol levels
  publication-title: Scientific reports
  doi: 10.1038/srep03034
  contributor:
    fullname: H Sumioka
– ident: pone.0259838.ref046
  doi: 10.1145/3374920.3374938
– volume: 9
  start-page: 199
  issue: 4
  year: 2006
  ident: pone.0259838.ref004
  article-title: Examination stress as an ecological inducer of cortisol and psychological responses to stress in undergraduate students
  publication-title: Stress
  doi: 10.1080/10253890601029751
  contributor:
    fullname: N Weekes
– start-page: 1
  year: 2019
  ident: pone.0259838.ref035
  article-title: Defining pleasant touch stimuli: a systematic review and meta-analysis
  publication-title: Psychological research
  contributor:
    fullname: P Taneja
– volume: 34
  start-page: 185
  issue: 2
  year: 2010
  ident: pone.0259838.ref036
  article-title: The neurophysiology of unmyelinated tactile afferents
  publication-title: Neuroscience & Biobehavioral Reviews
  doi: 10.1016/j.neubiorev.2008.09.011
  contributor:
    fullname: H Olausson
– volume: 28
  start-page: 76
  issue: 1-2
  year: 1993
  ident: pone.0259838.ref089
  article-title: The ‘Trier Social Stress Test’–a tool for investigating psychobiological stress responses in a laboratory setting
  publication-title: Neuropsychobiology
  doi: 10.1159/000119004
  contributor:
    fullname: C Kirschbaum
– volume: 11
  start-page: e0146131
  issue: 1
  year: 2016
  ident: pone.0259838.ref005
  article-title: State anxiety and nonlinear dynamics of heart rate variability in students
  publication-title: PloS one
  doi: 10.1371/journal.pone.0146131
  contributor:
    fullname: DA Dimitriev
– volume: 4
  start-page: 61
  issue: 2
  year: 2008
  ident: pone.0259838.ref079
  article-title: Confidence intervals from normalized data: A correction to Cousineau (2005)
  publication-title: reason
  contributor:
    fullname: RD Morey
– volume: 83
  start-page: 535
  issue: 4
  year: 2013
  ident: pone.0259838.ref008
  article-title: Statistics anxiety, state anxiety during an examination, and academic achievement
  publication-title: British Journal of Educational Psychology
  doi: 10.1111/j.2044-8279.2012.02081.x
  contributor:
    fullname: D Macher
– volume: 177
  start-page: 169
  year: 2017
  ident: pone.0259838.ref012
  article-title: Touch between romantic partners: Being stroked is more pleasant than stroking and decelerates heart rate
  publication-title: Physiology & behavior
  doi: 10.1016/j.physbeh.2017.05.006
  contributor:
    fullname: C Triscoli
– volume: 115
  start-page: 1397
  issue: 10
  year: 2005
  ident: pone.0259838.ref011
  article-title: Cortisol decreases and serotonin and dopamine increase following massage therapy
  publication-title: International Journal of Neuroscience
  doi: 10.1080/00207450590956459
  contributor:
    fullname: T Field
– volume: 68
  start-page: 331
  issue: 3
  year: 1987
  ident: pone.0259838.ref084
  article-title: Evidence for individuality of breathing patterns in resting healthy man
  publication-title: Respiration physiology
  doi: 10.1016/S0034-5687(87)80018-X
  contributor:
    fullname: S Shea
– volume: 12
  start-page: e0171220
  issue: 2
  year: 2017
  ident: pone.0259838.ref009
  article-title: Test anxiety in medical school is unrelated to academic performance but correlates with an effort/reward imbalance
  publication-title: PloS one
  doi: 10.1371/journal.pone.0171220
  contributor:
    fullname: H Hahn
– volume: 2018
  year: 2018
  ident: pone.0259838.ref033
  article-title: Examination stress results in attentional bias and altered neural reactivity in test-anxious individuals
  publication-title: Neural plasticity
  doi: 10.1155/2018/3281040
  contributor:
    fullname: X Zhang
– ident: pone.0259838.ref064
  doi: 10.1145/3334480.3382938
– volume: 128
  start-page: 71
  year: 2017
  ident: pone.0259838.ref014
  article-title: Heart rate variability is enhanced by long-lasting pleasant touch at CT-optimized velocity
  publication-title: Biological psychology
  doi: 10.1016/j.biopsycho.2017.07.007
  contributor:
    fullname: C Triscoli
– volume-title: Ganong’s review of medical physiology
  year: 2019
  ident: pone.0259838.ref081
  contributor:
    fullname: KE Barrett
– volume: 41
  start-page: 46
  issue: 10
  year: 2015
  ident: pone.0259838.ref032
  article-title: Using a robotic cat in dementia care: a pilot study
  publication-title: Journal of gerontological nursing
  doi: 10.3928/00989134-20150806-44
  contributor:
    fullname: C Gustafsson
– volume: 67
  start-page: 566
  issue: 3
  year: 2006
  ident: pone.0259838.ref056
  article-title: Physiology of long pranayamic breathing: neural respiratory elements may provide a mechanism that explains how slow deep breathing shifts the autonomic nervous system
  publication-title: Medical hypotheses
  doi: 10.1016/j.mehy.2006.02.042
  contributor:
    fullname: R Jerath
– volume: 9
  start-page: 1
  issue: 1
  year: 2019
  ident: pone.0259838.ref041
  article-title: Cardiac interaction between mother and infant: enhancement of heart rate variability
  publication-title: Scientific reports
  doi: 10.1038/s41598-019-56204-5
  contributor:
    fullname: A Suga
– volume: 34
  start-page: 27
  issue: 1
  year: 2015
  ident: pone.0259838.ref022
  article-title: Physiological effects of a companion robot on blood pressure of older people in residential care facility: a pilot study
  publication-title: Australasian journal on ageing
  doi: 10.1111/ajag.12099
  contributor:
    fullname: H Robinson
– volume: 12
  start-page: e0173457
  issue: 3
  year: 2017
  ident: pone.0259838.ref034
  article-title: C-tactile afferent stimulating touch carries a positive affective value
  publication-title: PloS one
  doi: 10.1371/journal.pone.0173457
  contributor:
    fullname: R Pawling
– volume: 3
  start-page: 27
  issue: 1
  year: 2019
  ident: pone.0259838.ref021
  article-title: Designing for playfulness through compassion: design for advanced dementia
  publication-title: Design for Health
  doi: 10.1080/24735132.2019.1593295
  contributor:
    fullname: C Treadaway
– volume: 7
  start-page: 1
  issue: 1
  year: 2017
  ident: pone.0259838.ref019
  article-title: The calming effect of a new wearable device during the anticipation of public speech
  publication-title: Scientific reports
  doi: 10.1038/s41598-017-02274-2
  contributor:
    fullname: RT Azevedo
– ident: pone.0259838.ref087
– volume: 25
  start-page: 215
  issue: 2
  year: 2012
  ident: pone.0259838.ref029
  article-title: Associations between the psychological characteristics of the human–dog relationship and oxytocin and cortisol levels
  publication-title: Anthrozoös
  doi: 10.2752/175303712X13316289505468
  contributor:
    fullname: L Handlin
– volume: 57
  start-page: 1442
  issue: 9
  year: 2012
  ident: pone.0259838.ref085
  article-title: Breathing movements of the chest and abdominal wall in healthy subjects
  publication-title: Respiratory care
  doi: 10.4187/respcare.01655
  contributor:
    fullname: H Kaneko
– volume: 15
  start-page: 194
  issue: 3
  year: 2008
  ident: pone.0259838.ref092
  article-title: The brief resilience scale: assessing the ability to bounce back
  publication-title: International journal of behavioral medicine
  doi: 10.1080/10705500802222972
  contributor:
    fullname: BW Smith
– ident: pone.0259838.ref076
– ident: pone.0259838.ref066
  doi: 10.1145/2851581.2892452
– volume: 70
  start-page: 976
  issue: 9
  year: 2008
  ident: pone.0259838.ref010
  article-title: Influence of a “warm touch” support enhancement intervention among married couples on ambulatory blood pressure, oxytocin, alpha amylase, and cortisol
  publication-title: Psychosomatic medicine
  doi: 10.1097/PSY.0b013e318187aef7
  contributor:
    fullname: J Holt-Lunstad
– ident: pone.0259838.ref097
  doi: 10.36227/techrxiv.14601192.v1
– volume: 40
  start-page: 1543
  issue: 8
  year: 2006
  ident: pone.0259838.ref093
  article-title: Measuring mindfulness—the Freiburg mindfulness inventory (FMI)
  publication-title: Personality and individual differences
  doi: 10.1016/j.paid.2005.11.025
  contributor:
    fullname: H Walach
– volume: 97
  start-page: 268
  issue: 2
  year: 2005
  ident: pone.0259838.ref007
  article-title: Test anxiety and academic performance in undergraduate and graduate students
  publication-title: Journal of educational Psychology
  doi: 10.1037/0022-0663.97.2.268
  contributor:
    fullname: MS Chapell
– volume: 6
  start-page: 1986
  year: 2016
  ident: pone.0259838.ref025
  article-title: The neurobiology shaping affective touch: expectation, motivation, and meaning in the multisensory context
  publication-title: Frontiers in psychology
  doi: 10.3389/fpsyg.2015.01986
  contributor:
    fullname: DM Ellingsen
– volume: 8
  start-page: 119
  issue: 1
  year: 2015
  ident: pone.0259838.ref067
  article-title: Tactile phantom sensation for coaching respiration timing
  publication-title: IEEE transactions on haptics
  doi: 10.1109/TOH.2015.2396896
  contributor:
    fullname: TG Sato
– volume: 28
  start-page: 1071
  issue: 7
  year: 2008
  ident: pone.0259838.ref099
  article-title: Anxiety in dementia: a critical review
  publication-title: Clinical psychology review
  doi: 10.1016/j.cpr.2008.02.008
  contributor:
    fullname: PJ Seignourel
– ident: pone.0259838.ref088
– volume: 2
  start-page: 344
  year: 2016
  ident: pone.0259838.ref016
  article-title: Keep calm and cuddle on: social touch as a stress buffer
  publication-title: Adaptive Human Behavior and Physiology
  doi: 10.1007/s40750-016-0052-x
  contributor:
    fullname: I Morrison
– volume: 8
  start-page: 36
  issue: 2
  year: 2019
  ident: pone.0259838.ref026
  article-title: Psychophysiological effects of human-dog interaction in university students exposed to a stress-induced situation using the Trier Social Stress Test (TSST)
  publication-title: Human Animal Interaction Bulletin
  contributor:
    fullname: R Martos-Montes
– volume: 16
  start-page: 1145
  issue: 11
  year: 2010
  ident: pone.0259838.ref052
  article-title: Effects of yoga versus walking on mood, anxiety, and brain GABA levels: a randomized controlled MRS study
  publication-title: The Journal of Alternative and Complementary Medicine
  doi: 10.1089/acm.2010.0007
  contributor:
    fullname: CC Streeter
– volume: 110
  start-page: 2666
  issue: 5
  year: 2001
  ident: pone.0259838.ref030
  article-title: The felid purr: A healing mechanism?
  publication-title: The Journal of the Acoustical Society of America
  doi: 10.1121/1.4777098
  contributor:
    fullname: E von Muggenthaler
– ident: pone.0259838.ref071
– ident: pone.0259838.ref094
– ident: pone.0259838.ref027
– volume: 53
  start-page: 329
  issue: 4
  year: 2017
  ident: pone.0259838.ref059
  article-title: The effectiveness of diaphragmatic breathing relaxation training for reducing anxiety
  publication-title: Perspectives in psychiatric care
  doi: 10.1111/ppc.12184
  contributor:
    fullname: YF Chen
– volume: 67
  start-page: 531
  issue: 4
  year: 2005
  ident: pone.0259838.ref013
  article-title: Effects of partner support on resting oxytocin, cortisol, norepinephrine, and blood pressure before and after warm partner contact
  publication-title: Psychosomatic medicine
  doi: 10.1097/01.psy.0000170341.88395.47
  contributor:
    fullname: KM Grewen
– volume: 31
  start-page: 301
  issue: 3
  year: 1992
  ident: pone.0259838.ref091
  article-title: The development of a six-item short-form of the state scale of the Spielberger State—Trait Anxiety Inventory (STAI)
  publication-title: British journal of clinical Psychology
  doi: 10.1111/j.2044-8260.1992.tb00997.x
  contributor:
    fullname: TM Marteau
– volume: 69
  start-page: 5
  issue: 1
  year: 2005
  ident: pone.0259838.ref038
  article-title: More frequent partner hugs and higher oxytocin levels are linked to lower blood pressure and heart rate in premenopausal women
  publication-title: Biological psychology
  doi: 10.1016/j.biopsycho.2004.11.002
  contributor:
    fullname: KC Light
– volume: 33
  start-page: 281
  issue: 5
  year: 2011
  ident: pone.0259838.ref006
  article-title: Exam anxiety induces significant blood pressure and heart rate increase in college students
  publication-title: Clinical and experimental hypertension
  doi: 10.3109/10641963.2010.531850
  contributor:
    fullname: Z Zhang
– volume: 60
  start-page: 451
  year: 2016
  ident: pone.0259838.ref086
  article-title: Abdominal wall muscle elasticity and abdomen local stiffness on healthy volunteers during various physiological activities
  publication-title: Journal of the mechanical behavior of biomedical materials
  doi: 10.1016/j.jmbbm.2016.03.001
  contributor:
    fullname: D Tran
– volume: 29
  start-page: 123
  issue: 3
  year: 2003
  ident: pone.0259838.ref039
  article-title: Warm partner contact is related to lower cardiovascular reactivity
  publication-title: Behavioral medicine
  doi: 10.1080/08964280309596065
  contributor:
    fullname: KM Grewen
– ident: pone.0259838.ref075
  doi: 10.1145/2971485.2996727
– volume: 2
  start-page: 1
  issue: 1
  year: 2018
  ident: pone.0259838.ref069
  article-title: Just breathe: In-car interventions for guided slow breathing
  publication-title: Proceedings of the ACM on Interactive, Mobile, Wearable and Ubiquitous Technologies
  doi: 10.1145/3191760
  contributor:
    fullname: PE Paredes
– ident: pone.0259838.ref062
  doi: 10.1145/3170427.3188616
– volume: 34
  issue: 2
  year: 2004
  ident: pone.0259838.ref055
  article-title: Application of the method of spectral analysis of heart rate variability during effects assessment of selected breathing techniques on functional changes in the autonomous nervous system
  publication-title: Acta Universitatis Palackianae Olomucensis Gymnica
  contributor:
    fullname: P Kolisko
– start-page: 100996
  year: 2020
  ident: pone.0259838.ref037
  article-title: Infants Show Physiological Responses Specific to Parental Hugs
  publication-title: Iscience
  doi: 10.1016/j.isci.2020.100996
  contributor:
    fullname: S Yoshida
– volume: 25
  start-page: 25
  issue: 1
  year: 2012
  ident: pone.0259838.ref028
  article-title: Effects of presence of a familiar pet dog on regional cerebral activity in healthy volunteers: A positron emission tomography study
  publication-title: Anthrozoös
  doi: 10.2752/175303712X13240472427311
  contributor:
    fullname: A Sugawara
– volume: 19
  start-page: 979
  issue: 3
  year: 2014
  ident: pone.0259838.ref044
  article-title: Mimo Pillow—An Intelligent Cushion Designed With Maternal Heart Beat Vibrations for Comforting Newborn Infants
  publication-title: IEEE journal of biomedical and health informatics
  doi: 10.1109/JBHI.2014.2349153
  contributor:
    fullname: W Chen
– ident: pone.0259838.ref090
  doi: 10.1002/9780470479216.corpsy0943
– ident: pone.0259838.ref077
  doi: 10.1145/3275476.3275492
– volume: 158
  start-page: 105
  issue: 1-2
  year: 2010
  ident: pone.0259838.ref015
  article-title: Physiological responses to touch massage in healthy volunteers
  publication-title: Autonomic Neuroscience
  doi: 10.1016/j.autneu.2010.06.011
  contributor:
    fullname: L Lindgren
– volume: 78
  start-page: 571
  issue: 5
  year: 2012
  ident: pone.0259838.ref053
  article-title: Effects of yoga on the autonomic nervous system, gamma-aminobutyric-acid, and allostasis in epilepsy, depression, and post-traumatic stress disorder
  publication-title: Medical hypotheses
  doi: 10.1016/j.mehy.2012.01.021
  contributor:
    fullname: C Streeter
– volume: 56
  start-page: 855
  issue: 5
  year: 1994
  ident: pone.0259838.ref045
  article-title: The breathing bear: effects on respiration in premature infants
  publication-title: Physiology & behavior
  doi: 10.1016/0031-9384(94)90315-8
  contributor:
    fullname: EW Ingersoll
– volume: 77
  start-page: 1548
  issue: 3
  year: 1994
  ident: pone.0259838.ref043
  article-title: Entrainment of respiration to rocking in premature infants: coherence analysis
  publication-title: Journal of Applied Physiology
  doi: 10.1152/jappl.1994.77.3.1548
  contributor:
    fullname: MP Sammon
– volume: 13
  start-page: 298
  issue: 4
  year: 2017
  ident: pone.0259838.ref058
  article-title: The physiological effects of slow breathing in the healthy human
  publication-title: Breathe
  doi: 10.1183/20734735.009817
  contributor:
    fullname: MA Russo
– ident: pone.0259838.ref002
– volume: 120
  start-page: 115
  issue: 2
  year: 2004
  ident: pone.0259838.ref060
  article-title: Effect of short-term practice of breathing exercises on autonomic functions in normal human volunteers
  publication-title: Indian Journal of Medical Research
  contributor:
    fullname: GK Pal
– ident: pone.0259838.ref072
  doi: 10.1145/1979742.1979831
– volume: 85
  start-page: 348
  issue: 2
  year: 2003
  ident: pone.0259838.ref095
  article-title: Individual differences in two emotion regulation processes: implications for affect, relationships, and well-being
  publication-title: Journal of personality and social psychology
  doi: 10.1037/0022-3514.85.2.348
  contributor:
    fullname: JJ Gross
– volume: 55
  start-page: 569
  issue: 2
  year: 2017
  ident: pone.0259838.ref031
  article-title: The utilization of robotic pets in dementia care
  publication-title: Journal of alzheimer’s disease
  doi: 10.3233/JAD-160703
  contributor:
    fullname: S Petersen
– volume: 7
  start-page: 537
  year: 2016
  ident: pone.0259838.ref050
  article-title: Intimacy in phone conversations: anxiety reduction for danish seniors with hugvie
  publication-title: Frontiers in psychology
  doi: 10.3389/fpsyg.2016.00537
  contributor:
    fullname: R Yamazaki
– ident: pone.0259838.ref098
  doi: 10.1109/EMBC44109.2020.9175900
– ident: pone.0259838.ref063
  doi: 10.1145/3290605.3300687
– ident: pone.0259838.ref018
– ident: pone.0259838.ref017
  doi: 10.7551/mitpress/9959.001.0001
– volume: 10
  start-page: 2082
  issue: 10
  year: 2019
  ident: pone.0259838.ref096
  article-title: Heart Rate Variability of Various Video-Aided Mindful Deep Breathing Durations and Its Impact on Depression, Anxiety, and Stress Symptom Severity
  publication-title: Mindfulness
  doi: 10.1007/s12671-019-01178-8
  contributor:
    fullname: KS Cheng
– volume: 7
  start-page: 108
  issue: 2
  year: 2015
  ident: pone.0259838.ref023
  article-title: Design and evaluation of a touch-centered calming interaction with a social robot
  publication-title: IEEE Transactions on Affective Computing
  doi: 10.1109/TAFFC.2015.2457893
  contributor:
    fullname: YS Sefidgar
– volume: 2013
  year: 2013
  ident: pone.0259838.ref082
  article-title: Cardiovascular and respiratory effect of yogic slow breathing in the yoga beginner: what is the best approach?
  publication-title: Evidence-Based Complementary and Alternative Medicine
  doi: 10.1155/2013/743504
  contributor:
    fullname: H Mason
– volume: 8
  start-page: 874
  year: 2017
  ident: pone.0259838.ref080
  article-title: The effect of diaphragmatic breathing on attention, negative affect and stress in healthy adults
  publication-title: Frontiers in psychology
  doi: 10.3389/fpsyg.2017.00874
  contributor:
    fullname: X Ma
– volume: 108
  start-page: 132
  year: 2015
  ident: pone.0259838.ref042
  article-title: Whose clock makes yours tick? How maternal cardiorespiratory physiology influences newborns’ heart rate variability
  publication-title: Biological psychology
  doi: 10.1016/j.biopsycho.2015.04.001
  contributor:
    fullname: M Van Puyvelde
SSID ssj0053866
Score 2.482002
Snippet Anxiety disorders affect approximately one third of people during their lifetimes and are the ninth leading cause of global disability. Current treatments...
SourceID plos
doaj
pubmedcentral
proquest
gale
crossref
pubmed
SourceType Open Website
Open Access Repository
Aggregation Database
Index Database
StartPage e0259838
SubjectTerms Anxiety
Anxiety - therapy
Anxiety disorders
Biology and Life Sciences
Blood pressure
Care and treatment
Cognition & reasoning
Cushions
Design and construction
Engineering and Technology
Experiments
Haptic interfaces
Haptics
Haptics technology
Heart rate
Humans
Interfaces
Laboratories
Mathematics
Medicine and Health Sciences
Mental disorders
Mental health
Pharmacology
Physiology
Pneumatic chambers
Prototypes
Robotics
Social Sciences
Stress
Students
Supervisors
Tactile stimuli
Touch
Visual stimuli
SummonAdditionalLinks – databaseName: DOAJ Directory of Open Access Journals
  dbid: DOA
  link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwrV1Nb9QwELXQnrggyldDWzAICTik3fgz5rZAq4IESEBRb5Ht2O1KJVk1WYmfz0ySjTaoEhy4reK30e6bsWcszzwT8oKbGH2QPlVe21Q4Xaa5CGAQK1lgkWkWscH502d1eiY-nsvzrau-sCaslwfuiTsSpTbSaZvPoxHewIYtRldiO6koHQS_bvXN5GYz1a_BMIuVGhrluM6OBrscruoqHEKUNzn2o2wFok6vf1yVZ6ururkp5fyzcnIrFJ3cJXeGHJIu-t--Q26F6h7ZGWZpQ18NUtKv75PjBQUb_ITwRC_XF2_o-65eg9qqpOBhy_4-JVpHammLHQ5XgdplSdua4qkN4H5hSecDcnZy_P3daTpcnJB6ZVibQlIVgtTG4zEdZGwlfLCliDnE8rnRXsKmg5dZ1NHbGOdOuLnhQjkdA0O5dv6QzCqgapfQKAGRRca9iyKPmUO9P8lldCrIYHlC0g2LxarXxyi6QzIN-4qejgJZLwbWE_IWqR6xqG7dPQCbF4PNi7_ZPCFP0VBF3yo6ztFioYxiLIMkKiHPOwQqXFRYQnNh101TfPjy4x9A375OQC8HUKzB5N4ObQvwn1A5a4LcnyBhnvrJ8C661YaVpmCKa6kZ0xl8c-NqNw8_G4fxpVgWV4V63WFyPCzTJiGPes8cmcWLDzgXIiF64rMT6qcj1fKyExjPDSSiQj7-H7baI7cZdoxg2Z7ZJ7P2eh0OII9r3ZNuyv4GiFZERw
  priority: 102
  providerName: Directory of Open Access Journals
– databaseName: ProQuest Central
  dbid: BENPR
  link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwjV3Nb9MwFLdGd4HDxMbHAgMMQgIOWRvHjmMuqINNBWkDDYZ2i-zE7iqNpCypxJ_Pe4lTFjQhblX8S9S8D7_nvC9CXsbKudyKPExyqUNuZBGm3AJDtGCWOSaZwwLn45NkdsY_nYvzDTLra2EwrbLfE9uNuqhy_EY-ZkkshWRMRmNt8CtA3ozfLX-GOD8K46x-mMYtsskijgHbzYPDky-n_a4Mep0kvnQuhmd4Tu0vq9Lug91XKVaoXDNNbQf_9T49Wl5W9U1O6N-5lNeM09FdsuW9SjrtxGCbbNhyh9w5XrdkrXfIttfimr72rabf3COHUwo8-gHmi16s5m_phzafg-qyoCCBi27eEq0c1bTBCohLS_WioE1FMaoDuF-Y8nmfnB0dfns_C_1ghTBPFGtCcLqsFVLlGMYDj66AH7rgLgVbP1EyF3AoiYvISZdr5yaGm4mKeWKkswzbuccPyKgEwu0S6gQgIsfi3DieushgP0ARC2cSK6yOAxL2NM2WXf-MrA2iSTh3dMTJkAeZ50FADpDwayx2v24vVFfzzCtTxguphJE6nTjFcwWHeOdMgSXGvDDgEAXkGbIt60pJ1zqcTROVMBaBkxWQFy0CO2CUmGIz16u6zj5-_v4foK-nA9ArD3IVSqX2ZQ3wTthZa4DcGyBBj_PB8i4KWU-VOvsj8XBnL3g3Lz9fL-NDMW2utNWqxaQYTJMqIA87OV1TFgcjxDHnAZEDCR6QfrhSLi7aBuSpAkeVi0f__luPyW2GtSKYsKf2yKi5Wtkn4ME15qlXzt8u20V5
  priority: 102
  providerName: ProQuest
– databaseName: Scholars Portal Journals (Open Access)
  dbid: M48
  link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwrV3di9NAEF_O-uKLeH5d9NRVBPUhR7Mf2awgUvWOUzgFtXJvYXez2yvUpDYtnP-9M0kajFTwwbeS_W2gv5nJzjJfhDzlOgTnpYtTp0wsrCriTHgQiJHMs8AUC1jgfPYxPZ2KD-fyfI9sZ7Z2BNY7r3Y4T2q6Whxd_vj5Ggz-VTO1QSXbTUfLqvRHcIbrjGdXyFUmuECdPxN9XAGsO027Arq_7RwcUE0f__5rPVouqnqXK_pnRuVvR9TJDXK98y3ppFWGfbLny5tkv7Pemj7vWky_uEWOJxRk8x2OLXqxmb2k75o8DmrKgoLmzds5S7QK1NA1Vj4sPDXzgq4ritEcwF1iqudtMj05_vr2NO4GKsQu1Wwdg7PlvVTaYfgOPLkCfphChAzO-LFWTsJlhBdJUMGZEMZW2LEGDq0KnmEbd36HjEqg6oDQIAGRBMadDSILicU-gJLLYFMvveERibcs5su2b0beBM8U3DdaOnJkPe9Yj8gbpLrHYtfr5kG1muWdEeWiUFpaZbJx0MJpuLyHYAssLRaFBUcoIo9QUHlbQtrbbj5JdcpYAs5VRJ40COx8UWJqzcxs6jp__-nbP4C-fB6AnnWgUIHInenKGeA_YUetAfJwgAT7dYPlA1SrLSt1zlKupGJMJbBzq2q7lx_3y_hSTJcrfbVpMBkG0ZSOyN1WM3tmcSAC50JERA10dkD9cKWcXzSNxzMNDqqQ9_6HrO6TawwrSTCdTx-S0Xq18Q_Av1vbh43J_gLuY06w
  priority: 102
  providerName: Scholars Portal
Title A calming hug: Design and validation of a tactile aid to ease anxiety
URI https://www.ncbi.nlm.nih.gov/pubmed/35263344
https://www.proquest.com/docview/2637572271/abstract/
https://search.proquest.com/docview/2638013279
https://pubmed.ncbi.nlm.nih.gov/PMC8906645
https://doaj.org/article/4d795b7a80f94c9888ffbd35954db317
http://dx.doi.org/10.1371/journal.pone.0259838
Volume 17
hasFullText 1
inHoldings 1
isFullTextHit
isPrint
link http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1Lb9NAEF614cIFUV4NlLAgJODgJN6H18stDQkFKaUqFPVmede7aaTEjppE4ucz40eEUQ-IyyrKfo7seXhmszPfEvKWa--tkzaIrEoDYVQWxMKBQlLJHPNMMY8NzrPz6OxKfL2W1wdENr0wZdG-NYt-vlz188VNWVu5XtlBUyc2uJiNYw2BUsjBITlUnDdL9Or1Cw4cRXWPHFfhoFZJf13krg8BXsccz-hDWnjOhWiFo5K1f_9u7qyXxeauxPPv-sk_AtL0IXlQZ5J0VN3xETlw-SNyVPvqhr6vCaU_PCaTEQVNrCBI0Zvd_CP9VFZt0DTPKNjZojpViRaepnSLfQ5LR9NFRrcFxb0bwP3Cws4n5Go6-TE-C-rjEwIbabYN4BGdk0pb3KyDvC2DD2kmfAwRfaiVlbD04Fnolbep90MjzFBzERnlHUPSdv6UdHKQ2jGhXgIi9Ixb40XsQ4Osf5JLbyInXcq7JGikmKwrloyk3CpTsLqoxJGgApJaAV1yiqLeY5HjuvyiuJ0ntaYTkSktjUrjodfCaliqe28ybCQWmYG0p0teoaKSqmF076nJKNIRYyGkUl3ypkQgz0WOhTTzdLfZJF--_fwH0PfLFuhdDfIFqNymdfMCPBPyZ7WQJy0keKttTR-jWTVS2SRghkoqxlQIVzamdvf06_00_igWx-Wu2JWYGLfMlO6SZ5Vl7iXb2HmXqJbNtkTfngGvK2nGay97_t9XviD3GTaLYMWePiGd7e3OvYQUbmt64LjXCsZ4HOI4_dwj904n5xeXvfJPERhnIu6Vjv0bILxK0Q
link.rule.ids 230,315,733,786,790,870,891,2115,2236,12083,12250,12792,21416,24346,27957,27958,31754,31755,33301,33302,33408,33409,33779,33780,43345,43614,43635,43840,53827,53829,74102,74371,74392,74659
linkProvider National Library of Medicine
linkToHtml http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwjV3db9MwELegPAAPExsfyxjMICTgIVvjjzjmBZWxqYN1SLChvUWJY3eVRlKWVuLP5y5xw4ImxFtV_1q19-E75-5-JuQV184ZK00YG5WFIldFmAgLCskks8wxxRwOOE9O4vGZ-HQuz_0Dt9q3Va72xGajLiqDz8j3WMyVVIyp6P38Z4i3RmF11V-hcZvcERwCDU6K73ctHuDLcezH5biK9rx2dudVaXch1usEp1KuhaOGtb_bmwfzy6q-KfH8u3_yWkA6fEDWfCZJR63q18ktW26Q-5OOhrXeIOvec2v6xtNLv31IDkYU9PIDQha9WE7f0Y9NDwfNyoKC1c3aO5Zo5WhGFzj1cGlpNivooqJYyQHcL2zzfETODg9O98ehv0whNLFmixASLWul0gZLd5DFFfAiK4RLIL4PtTISDiK8iJxyJnNumIt8qLmIc-UsQwp3_pgMShDcJqFOAiJyjJvcicRFOXIASi5dHltpMx6QcCXTdN5yZqRN4UzBWaMVToo6SL0OAvIBBd9hkfG6eaO6mqbegVJRKC1zlSVDp4XRcHB3Li9wrFgUOSRBAdlBtaXt-Gjnt-ko1jFjESRWAXnZIJD1osS2mmm2rOv06Mv3_wB9-9oDvfYgV4EBmMyPMsB_QjatHnK7hwTfNb3lTTSylVTq9I-VwydXhnfz8otuGb8UW-VKWy0bTIIFNKUD8qS1006yeBkC50IERPUsuCf6_ko5u2hIxxMNyamQW__-WTvk7vh0cpweH518fkruMZwVwYY9vU0Gi6ulfQYZ3CJ_3rjpb3-EQxE
linkToPdf http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwjV3db9MwELegSAgeEBsfCwxmEBLwkK117DjmBRW2aQM2EGyob1bs2F2lkZSllfjzuUvcsKAJ8VbVv0btffjO9d3vCHmRKO-tEzZOrcxjbmQRZ9yBQnLBHPNMMo8NzkfH6cEp_zARk1D_VIeyytWe2GzURWXxP_IdliZSSMbkaMeHsogvu_tv5z9jnCCFN61hnMZ1cgOi5BCnGchJd_gCv07T0DqXwDOCprbnVem2Ie6rDDtULoWmhsG_26cH8_OqvioJ_buW8lJw2r9L7oSsko5bM1gj11y5Tm4fdZSs9TpZC15c01eBavr1PbI3pqCjHxC-6Nly-obuNvUcNC8LChY4a-ct0crTnC6wA-Lc0XxW0EVF8VYHcL-w5PM-Od3fO3l_EIfBCrFNFVvEkHQ5J6SyeI0HGV0BL_KC-wxi_VBJK-BQkhQjL73NvR8aboYq4amR3jGkc08ekEEJgtsg1AtAjDxLrPE88yODfIAiEd6kTrg8iUi8kqmet_wZurlEk3DuaIWjUQc66CAi71DwHRbZr5s3qoupDs6keSGVMDLPhl5xq-AQ770psMWYFwYSoohsodp020ra-bAepyplbARJVkSeNwhkwCjRlqb5sq714efv_wH69rUHehlAvgIDsHloa4DfhMxaPeRmDwl-bHvLG2hkK6nU-o_FwydXhnf18rNuGR-KZXOlq5YNJsPLNKki8rC1006yOBghSTiPiOxZcE_0_ZVydtYQkGcKElUuHv37a22Rm-Ch-tPh8cfH5BbDthGs3VObZLC4WLonkMwtzNPGS38DKUhHcg
openUrl ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=A+calming+hug%3A+Design+and+validation+of+a+tactile+aid+to+ease+anxiety&rft.jtitle=PloS+one&rft.au=Alice+C+Haynes&rft.au=Annie+Lywood&rft.au=Emily+M+Crowe&rft.au=Jessica+L+Fielding&rft.date=2022-03-09&rft.pub=Public+Library+of+Science+%28PLoS%29&rft.eissn=1932-6203&rft.volume=17&rft.issue=3&rft.spage=e0259838&rft_id=info:doi/10.1371%2Fjournal.pone.0259838&rft.externalDBID=DOA&rft.externalDocID=oai_doaj_org_article_4d795b7a80f94c9888ffbd35954db317
thumbnail_l http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=1932-6203&client=summon
thumbnail_m http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=1932-6203&client=summon
thumbnail_s http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=1932-6203&client=summon