Renal and renal sinus fat volumes as quantified by magnetic resonance imaging in subjects with prediabetes, diabetes, and normal glucose tolerance

• Published in: PloS one Vol. 15; no. 2; p. e0216635
• Main Authors: Notohamiprodjo, Mike, Goepfert, Martin, Will, Susanne, Lorbeer, Roberto, Schick, Fritz, Rathmann, Wolfgang, Martirosian, Petros, Peters, Annette, Müller-Peltzer, Katharina, Helck, Andreas, Rospleszcz, Susanne, Bamberg, Fabian
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 19.02.2020; Public Library of Science (PLoS)
• Subjects: Adipose tissue; Adipose Tissue - diagnostic imaging; Aged; Biological markers; Biology and Life Sciences; Biomarkers; Blood Glucose - analysis; Chronic kidney failure; Correlation coefficient; Correlation coefficients; Creatinine; Diabetes; Diabetes mellitus; Diabetes Mellitus, Type 2 - diagnostic imaging; Diagnostic imaging; Diseases; Echo surveys; Female; Glucose; Glucose intolerance; Glucose tolerance; Glucose tolerance test; Humans; Hypertension; Image segmentation; Intolerance; Kidney - diagnostic imaging; Kidney diseases; Kidneys; Magnetic resonance; Magnetic Resonance Imaging; Male; Medical imaging; Medical research; Medicine and Health Sciences; Metabolic disorders; Middle Aged; Prediabetic state; Prediabetic State - diagnostic imaging; Regression analysis; Regression models; Research and Analysis Methods; Segmentation; Studies; Type 2 diabetes; Germany

We hypothesize that MRI-based renal compartment volumes, particularly renal sinus fat as locally and potentially independently acting perivascular fat tissue, increase with glucose intolerance. We therefore analyze the distribution of renal volumes in individuals with normal glucose levels and predi...