N-3 Polyunsaturated Fatty Acids Prevent Diabetic Retinopathy by Inhibition of Retinal Vascular Damage and Enhanced Endothelial Progenitor Cell Reparative Function - Tikhonenko, Maria; Lydic, Todd A.; Opreanu, Madalina; Li Calzi, Sergio; Bozack, Svetlana; McSorley, Kelly M.; Sochacki, Andrew L.; Faber, Matthew S.; Hazra, Sugata; Duclos, Shane; Guberski, Dennis; Reid, Gavin E.; et al. (PloS one, 2013)
Keywords: Analysis; Animal models; Animals; Bioindicators; Biology; Biomedical research; Blotting, Western; Bone marrow; Capillaries; Cells (biology); Colonies; Damage prevention; Degeneration; Diabetes; Diabetes mellitus; Diabetes Mellitus, Type 2 - complications; Diabetic retinopathy; Diabetic Retinopathy - diet therapy; Diabetic Retinopathy - etiology; Diabetic Retinopathy - metabolism; Diet; Docosahexaenoic acid; Docosahexaenoic Acids - metabolism; Docosahexaenoic Acids - pharmacology; Docosahexaenoic Acids - therapeutic use; Endothelial Cells - drug effects; Endothelium; Fatty acids; Inflammation; Inhibition; Intercellular adhesion molecule 1; Intercellular Adhesion Molecule-1 - metabolism; Interleukin; Interleukin 6; Interleukin-1beta - metabolism; Interleukin-6 - metabolism; Interleukins; Life span; Lipid metabolism; Medicine; Metabolic syndrome; Metabolism; mRNA; Omega 3 fatty acids; Osteoprogenitor cells; Pharmacology; Physiological aspects; Physiology; Polyunsaturated fatty acids; Prevention; Progenitor cells; Rats; Research design; Retina; Retinal Vessels - drug effects; Retinal Vessels - physiopathology; Retinopathy; RNA; Rodents; Soybeans; Sphingomyelin phosphodiesterase; Sphingomyelin Phosphodiesterase - metabolism; Stem Cells - drug effects; Trypsin; Type 2 diabetes; Unsaturated fatty acids; East Lansing Michigan; Florida; United States--US; Massachusetts; Michigan