Cost-effectiveness of internet-supported cognitive behavioral therapy for university students with anxiety symptoms: A Markov-model analysis
High prevalence of anxiety symptoms has been reported globally in the university students. Cognitive behavioral therapy (CBT) is the recognized treatment for anxiety and is traditionally conducted face-to-face (f-CBT). The efficacy of internet-based CBT (i-CBT) for anxiety has been extensively studi...
Saved in:
| Published in | PloS one Vol. 17; no. 5; p. e0268061 |
|---|---|
| Main Authors | , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
United States
Public Library of Science
05.05.2022
Public Library of Science (PLoS) |
| Subjects | |
| Online Access | Get full text |
| ISSN | 1932-6203 1932-6203 |
| DOI | 10.1371/journal.pone.0268061 |
Cover
Loading…
| Abstract | High prevalence of anxiety symptoms has been reported globally in the university students. Cognitive behavioral therapy (CBT) is the recognized treatment for anxiety and is traditionally conducted face-to-face (f-CBT). The efficacy of internet-based CBT (i-CBT) for anxiety has been extensively studied, yet evidence on its cost-effectiveness is scarce. We aimed to evaluate the cost-effectiveness of guided low-intensity i-CBT for university students with mild anxiety symptoms from the societal perspective of Hong Kong.
A 5-year Markov model was designed to compare outcomes of guided i-CBT and f-CBT in a hypothetical cohort of university students with mild anxiety symptoms. Model inputs of cost and healthcare resources associated with anxiety were retrospectively collected from a cohort of university students with anxiety symptoms. Clinical and utility model inputs were retrieved from published literature. Model outcome measures were anxiety-related total cost (including direct medical and indirect costs) and quality-adjusted life-year (QALY). Sensitivity analyses were performed to examine the robustness of base-case results.
In base-case analysis, i-CBT gained higher QALYs (2.9956 versus 2.9917) at lower total cost (US$6,101 versus US$6,246) than f-CBT. In one-way sensitivity analysis, the QALY gained by i-CBT was sensitive to the relative patient acceptance and adherence to CBT. In probabilistic sensitivity analysis, i-CBT was cost-effective in 90.9% of the time at the willingness-to-pay threshold of 138,210 per QALY (3× GDP per capita in Hong Kong). The probability of i-CBT to be cost-effective was 99.9% at a willingness-to-pay threshold of zero.
Guided i-CBT appears to be cost-saving and effective for management of university students with mild symptoms of anxiety from the societal perspective of Hong Kong. The cost-effectiveness of i-CBT is highly subject to the individual acceptance and adherence of CBT delivered by the internet platform. |
|---|---|
| AbstractList | High prevalence of anxiety symptoms has been reported globally in the university students. Cognitive behavioral therapy (CBT) is the recognized treatment for anxiety and is traditionally conducted face-to-face (f-CBT). The efficacy of internet-based CBT (i-CBT) for anxiety has been extensively studied, yet evidence on its cost-effectiveness is scarce. We aimed to evaluate the cost-effectiveness of guided low-intensity i-CBT for university students with mild anxiety symptoms from the societal perspective of Hong Kong.BACKGROUND AND AIMHigh prevalence of anxiety symptoms has been reported globally in the university students. Cognitive behavioral therapy (CBT) is the recognized treatment for anxiety and is traditionally conducted face-to-face (f-CBT). The efficacy of internet-based CBT (i-CBT) for anxiety has been extensively studied, yet evidence on its cost-effectiveness is scarce. We aimed to evaluate the cost-effectiveness of guided low-intensity i-CBT for university students with mild anxiety symptoms from the societal perspective of Hong Kong.A 5-year Markov model was designed to compare outcomes of guided i-CBT and f-CBT in a hypothetical cohort of university students with mild anxiety symptoms. Model inputs of cost and healthcare resources associated with anxiety were retrospectively collected from a cohort of university students with anxiety symptoms. Clinical and utility model inputs were retrieved from published literature. Model outcome measures were anxiety-related total cost (including direct medical and indirect costs) and quality-adjusted life-year (QALY). Sensitivity analyses were performed to examine the robustness of base-case results.METHODSA 5-year Markov model was designed to compare outcomes of guided i-CBT and f-CBT in a hypothetical cohort of university students with mild anxiety symptoms. Model inputs of cost and healthcare resources associated with anxiety were retrospectively collected from a cohort of university students with anxiety symptoms. Clinical and utility model inputs were retrieved from published literature. Model outcome measures were anxiety-related total cost (including direct medical and indirect costs) and quality-adjusted life-year (QALY). Sensitivity analyses were performed to examine the robustness of base-case results.In base-case analysis, i-CBT gained higher QALYs (2.9956 versus 2.9917) at lower total cost (US$6,101 versus US$6,246) than f-CBT. In one-way sensitivity analysis, the QALY gained by i-CBT was sensitive to the relative patient acceptance and adherence to CBT. In probabilistic sensitivity analysis, i-CBT was cost-effective in 90.9% of the time at the willingness-to-pay threshold of 138,210 per QALY (3× GDP per capita in Hong Kong). The probability of i-CBT to be cost-effective was 99.9% at a willingness-to-pay threshold of zero.RESULTSIn base-case analysis, i-CBT gained higher QALYs (2.9956 versus 2.9917) at lower total cost (US$6,101 versus US$6,246) than f-CBT. In one-way sensitivity analysis, the QALY gained by i-CBT was sensitive to the relative patient acceptance and adherence to CBT. In probabilistic sensitivity analysis, i-CBT was cost-effective in 90.9% of the time at the willingness-to-pay threshold of 138,210 per QALY (3× GDP per capita in Hong Kong). The probability of i-CBT to be cost-effective was 99.9% at a willingness-to-pay threshold of zero.Guided i-CBT appears to be cost-saving and effective for management of university students with mild symptoms of anxiety from the societal perspective of Hong Kong. The cost-effectiveness of i-CBT is highly subject to the individual acceptance and adherence of CBT delivered by the internet platform.CONCLUSIONSGuided i-CBT appears to be cost-saving and effective for management of university students with mild symptoms of anxiety from the societal perspective of Hong Kong. The cost-effectiveness of i-CBT is highly subject to the individual acceptance and adherence of CBT delivered by the internet platform. Background and aim High prevalence of anxiety symptoms has been reported globally in the university students. Cognitive behavioral therapy (CBT) is the recognized treatment for anxiety and is traditionally conducted face-to-face (f-CBT). The efficacy of internet-based CBT (i-CBT) for anxiety has been extensively studied, yet evidence on its cost-effectiveness is scarce. We aimed to evaluate the cost-effectiveness of guided low-intensity i-CBT for university students with mild anxiety symptoms from the societal perspective of Hong Kong. Methods A 5-year Markov model was designed to compare outcomes of guided i-CBT and f-CBT in a hypothetical cohort of university students with mild anxiety symptoms. Model inputs of cost and healthcare resources associated with anxiety were retrospectively collected from a cohort of university students with anxiety symptoms. Clinical and utility model inputs were retrieved from published literature. Model outcome measures were anxiety-related total cost (including direct medical and indirect costs) and quality-adjusted life-year (QALY). Sensitivity analyses were performed to examine the robustness of base-case results. Results In base-case analysis, i-CBT gained higher QALYs (2.9956 versus 2.9917) at lower total cost (US$6,101 versus US$6,246) than f-CBT. In one-way sensitivity analysis, the QALY gained by i-CBT was sensitive to the relative patient acceptance and adherence to CBT. In probabilistic sensitivity analysis, i-CBT was cost-effective in 90.9% of the time at the willingness-to-pay threshold of 138,210 per QALY (3x GDP per capita in Hong Kong). The probability of i-CBT to be cost-effective was 99.9% at a willingness-to-pay threshold of zero. Conclusions Guided i-CBT appears to be cost-saving and effective for management of university students with mild symptoms of anxiety from the societal perspective of Hong Kong. The cost-effectiveness of i-CBT is highly subject to the individual acceptance and adherence of CBT delivered by the internet platform. Background and aim High prevalence of anxiety symptoms has been reported globally in the university students. Cognitive behavioral therapy (CBT) is the recognized treatment for anxiety and is traditionally conducted face-to-face (f-CBT). The efficacy of internet-based CBT (i-CBT) for anxiety has been extensively studied, yet evidence on its cost-effectiveness is scarce. We aimed to evaluate the cost-effectiveness of guided low-intensity i-CBT for university students with mild anxiety symptoms from the societal perspective of Hong Kong. Methods A 5-year Markov model was designed to compare outcomes of guided i-CBT and f-CBT in a hypothetical cohort of university students with mild anxiety symptoms. Model inputs of cost and healthcare resources associated with anxiety were retrospectively collected from a cohort of university students with anxiety symptoms. Clinical and utility model inputs were retrieved from published literature. Model outcome measures were anxiety-related total cost (including direct medical and indirect costs) and quality-adjusted life-year (QALY). Sensitivity analyses were performed to examine the robustness of base-case results. Results In base-case analysis, i-CBT gained higher QALYs (2.9956 versus 2.9917) at lower total cost (US$6,101 versus US$6,246) than f-CBT. In one-way sensitivity analysis, the QALY gained by i-CBT was sensitive to the relative patient acceptance and adherence to CBT. In probabilistic sensitivity analysis, i-CBT was cost-effective in 90.9% of the time at the willingness-to-pay threshold of 138,210 per QALY (3× GDP per capita in Hong Kong). The probability of i-CBT to be cost-effective was 99.9% at a willingness-to-pay threshold of zero. Conclusions Guided i-CBT appears to be cost-saving and effective for management of university students with mild symptoms of anxiety from the societal perspective of Hong Kong. The cost-effectiveness of i-CBT is highly subject to the individual acceptance and adherence of CBT delivered by the internet platform. High prevalence of anxiety symptoms has been reported globally in the university students. Cognitive behavioral therapy (CBT) is the recognized treatment for anxiety and is traditionally conducted face-to-face (f-CBT). The efficacy of internet-based CBT (i-CBT) for anxiety has been extensively studied, yet evidence on its cost-effectiveness is scarce. We aimed to evaluate the cost-effectiveness of guided low-intensity i-CBT for university students with mild anxiety symptoms from the societal perspective of Hong Kong. A 5-year Markov model was designed to compare outcomes of guided i-CBT and f-CBT in a hypothetical cohort of university students with mild anxiety symptoms. Model inputs of cost and healthcare resources associated with anxiety were retrospectively collected from a cohort of university students with anxiety symptoms. Clinical and utility model inputs were retrieved from published literature. Model outcome measures were anxiety-related total cost (including direct medical and indirect costs) and quality-adjusted life-year (QALY). Sensitivity analyses were performed to examine the robustness of base-case results. In base-case analysis, i-CBT gained higher QALYs (2.9956 versus 2.9917) at lower total cost (US$6,101 versus US$6,246) than f-CBT. In one-way sensitivity analysis, the QALY gained by i-CBT was sensitive to the relative patient acceptance and adherence to CBT. In probabilistic sensitivity analysis, i-CBT was cost-effective in 90.9% of the time at the willingness-to-pay threshold of 138,210 per QALY (3× GDP per capita in Hong Kong). The probability of i-CBT to be cost-effective was 99.9% at a willingness-to-pay threshold of zero. Guided i-CBT appears to be cost-saving and effective for management of university students with mild symptoms of anxiety from the societal perspective of Hong Kong. The cost-effectiveness of i-CBT is highly subject to the individual acceptance and adherence of CBT delivered by the internet platform. Background and aimHigh prevalence of anxiety symptoms has been reported globally in the university students. Cognitive behavioral therapy (CBT) is the recognized treatment for anxiety and is traditionally conducted face-to-face (f-CBT). The efficacy of internet-based CBT (i-CBT) for anxiety has been extensively studied, yet evidence on its cost-effectiveness is scarce. We aimed to evaluate the cost-effectiveness of guided low-intensity i-CBT for university students with mild anxiety symptoms from the societal perspective of Hong Kong.MethodsA 5-year Markov model was designed to compare outcomes of guided i-CBT and f-CBT in a hypothetical cohort of university students with mild anxiety symptoms. Model inputs of cost and healthcare resources associated with anxiety were retrospectively collected from a cohort of university students with anxiety symptoms. Clinical and utility model inputs were retrieved from published literature. Model outcome measures were anxiety-related total cost (including direct medical and indirect costs) and quality-adjusted life-year (QALY). Sensitivity analyses were performed to examine the robustness of base-case results.ResultsIn base-case analysis, i-CBT gained higher QALYs (2.9956 versus 2.9917) at lower total cost (US$6,101 versus US$6,246) than f-CBT. In one-way sensitivity analysis, the QALY gained by i-CBT was sensitive to the relative patient acceptance and adherence to CBT. In probabilistic sensitivity analysis, i-CBT was cost-effective in 90.9% of the time at the willingness-to-pay threshold of 138,210 per QALY (3× GDP per capita in Hong Kong). The probability of i-CBT to be cost-effective was 99.9% at a willingness-to-pay threshold of zero.ConclusionsGuided i-CBT appears to be cost-saving and effective for management of university students with mild symptoms of anxiety from the societal perspective of Hong Kong. The cost-effectiveness of i-CBT is highly subject to the individual acceptance and adherence of CBT delivered by the internet platform. High prevalence of anxiety symptoms has been reported globally in the university students. Cognitive behavioral therapy (CBT) is the recognized treatment for anxiety and is traditionally conducted face-to-face (f-CBT). The efficacy of internet-based CBT (i-CBT) for anxiety has been extensively studied, yet evidence on its cost-effectiveness is scarce. We aimed to evaluate the cost-effectiveness of guided low-intensity i-CBT for university students with mild anxiety symptoms from the societal perspective of Hong Kong. A 5-year Markov model was designed to compare outcomes of guided i-CBT and f-CBT in a hypothetical cohort of university students with mild anxiety symptoms. Model inputs of cost and healthcare resources associated with anxiety were retrospectively collected from a cohort of university students with anxiety symptoms. Clinical and utility model inputs were retrieved from published literature. Model outcome measures were anxiety-related total cost (including direct medical and indirect costs) and quality-adjusted life-year (QALY). Sensitivity analyses were performed to examine the robustness of base-case results. In base-case analysis, i-CBT gained higher QALYs (2.9956 versus 2.9917) at lower total cost (US$6,101 versus US$6,246) than f-CBT. In one-way sensitivity analysis, the QALY gained by i-CBT was sensitive to the relative patient acceptance and adherence to CBT. In probabilistic sensitivity analysis, i-CBT was cost-effective in 90.9% of the time at the willingness-to-pay threshold of 138,210 per QALY (3x GDP per capita in Hong Kong). The probability of i-CBT to be cost-effective was 99.9% at a willingness-to-pay threshold of zero. Guided i-CBT appears to be cost-saving and effective for management of university students with mild symptoms of anxiety from the societal perspective of Hong Kong. The cost-effectiveness of i-CBT is highly subject to the individual acceptance and adherence of CBT delivered by the internet platform. Background and aim High prevalence of anxiety symptoms has been reported globally in the university students. Cognitive behavioral therapy (CBT) is the recognized treatment for anxiety and is traditionally conducted face-to-face (f-CBT). The efficacy of internet-based CBT (i-CBT) for anxiety has been extensively studied, yet evidence on its cost-effectiveness is scarce. We aimed to evaluate the cost-effectiveness of guided low-intensity i-CBT for university students with mild anxiety symptoms from the societal perspective of Hong Kong. Methods A 5-year Markov model was designed to compare outcomes of guided i-CBT and f-CBT in a hypothetical cohort of university students with mild anxiety symptoms. Model inputs of cost and healthcare resources associated with anxiety were retrospectively collected from a cohort of university students with anxiety symptoms. Clinical and utility model inputs were retrieved from published literature. Model outcome measures were anxiety-related total cost (including direct medical and indirect costs) and quality-adjusted life-year (QALY). Sensitivity analyses were performed to examine the robustness of base-case results. Results In base-case analysis, i-CBT gained higher QALYs (2.9956 versus 2.9917) at lower total cost (US$6,101 versus US$6,246) than f-CBT. In one-way sensitivity analysis, the QALY gained by i-CBT was sensitive to the relative patient acceptance and adherence to CBT. In probabilistic sensitivity analysis, i-CBT was cost-effective in 90.9% of the time at the willingness-to-pay threshold of 138,210 per QALY (3× GDP per capita in Hong Kong). The probability of i-CBT to be cost-effective was 99.9% at a willingness-to-pay threshold of zero. Conclusions Guided i-CBT appears to be cost-saving and effective for management of university students with mild symptoms of anxiety from the societal perspective of Hong Kong. The cost-effectiveness of i-CBT is highly subject to the individual acceptance and adherence of CBT delivered by the internet platform. |
| Audience | Academic |
| Author | Jiang, Xinchan Luk, Scotty W. C. Mak, Winnie W. S. You, Joyce H. S. Mak, Arthur D. P. Chow, Dilys Y. W. |
| AuthorAffiliation | 2 University Health Service, The Chinese University of Hong Kong, Hong Kong SAR, China 3 Department of Psychiatry, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong SAR, China Yamaguchi University: Yamaguchi Daigaku, JAPAN 4 Department of Psychology, Faculty of Social Science, The Chinese University of Hong Kong, Hong Kong SAR, China 1 School of Pharmacy, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong SAR, China |
| AuthorAffiliation_xml | – name: 3 Department of Psychiatry, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong SAR, China – name: Yamaguchi University: Yamaguchi Daigaku, JAPAN – name: 4 Department of Psychology, Faculty of Social Science, The Chinese University of Hong Kong, Hong Kong SAR, China – name: 2 University Health Service, The Chinese University of Hong Kong, Hong Kong SAR, China – name: 1 School of Pharmacy, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong SAR, China |
| Author_xml | – sequence: 1 givenname: Joyce H. S. orcidid: 0000-0002-5763-7403 surname: You fullname: You, Joyce H. S. – sequence: 2 givenname: Scotty W. C. surname: Luk fullname: Luk, Scotty W. C. – sequence: 3 givenname: Dilys Y. W. surname: Chow fullname: Chow, Dilys Y. W. – sequence: 4 givenname: Xinchan surname: Jiang fullname: Jiang, Xinchan – sequence: 5 givenname: Arthur D. P. surname: Mak fullname: Mak, Arthur D. P. – sequence: 6 givenname: Winnie W. S. surname: Mak fullname: Mak, Winnie W. S. |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/35511888$$D View this record in MEDLINE/PubMed |
| BookMark | eNqNk9tq3DAQhk1JaQ7tG5TWUCjthbeSLct2Lgoh9LCQEujpVsjSaFepLbmSvM2-Qx-6cncTdkMoxRcyo2_-Gf3MHCcHxhpIkqcYzXBR4TdXdnSGd7MhhmcopzWi-EFyhJsiz2iOioOd_8Pk2PsrhMqipvRRcliUJcZ1XR8lv8-tDxkoBSLoFRjwPrUq1SaAMxAyPw6DdQFkKuzC6IlJW1jylbaOd2lYguPDOlXWpaOJl87rsE59GCWY4NNfOixTbq41TNF1PwTb-9P0LP3E3Q-7ynoroYsA79Ze-8fJQ8U7D0-250ny7f27r-cfs4vLD_Pzs4tM0CYPWa4IrymmqhSc55gSIgmnpMmhVYTkigJvy6aUQPNSyqqBAkkMikamrltZFSfJ843u0FnPtkZ6Fj2MZtVNgyMx3xDS8is2ON1zt2aWa_Y3YN2CcRe06ICVCOFaYEIorQjHpK2hakVeFqLilWxF1Hq7rTa2PUgRjYnW7Ynu3xi9ZAu7Yg2qYjdTM6-2As7-HMEH1msvoOu4ATtOfVOEESJVE9EXd9D7X7elFjw-QBtlY10xibKzKo4SKuucRGp2DxU_Cb0WceqUjvG9hNd7CZEJcB0WfPSezb98_n_28vs--3KHXQLvwtLbbgzaGr8PPtt1-tbim3GPANkAwlnvHahbBCM2bdWNXWzaKrbdqph2eidN6MCn8tER3f07-Q9L8iut |
| CitedBy_id | crossref_primary_10_1097_MPG_0000000000003754 crossref_primary_10_2196_39248 crossref_primary_10_3280_rpc2_2023oa15915 crossref_primary_10_1016_j_jpain_2025_105375 crossref_primary_10_1177_07067437241261933 crossref_primary_10_2144_fsoa_2023_0104 crossref_primary_10_1186_s44247_024_00074_z crossref_primary_10_3390_nursrep15030091 crossref_primary_10_3389_fpsyg_2023_1202408 crossref_primary_10_1038_s44220_023_00106_z |
| Cites_doi | 10.2196/jmir.6737 10.1001/jamapsychiatry.2020.0940 10.1186/1471-244X-12-177 10.2196/23126 10.1016/j.janxdis.2013.09.009 10.1192/bjp.bp.115.171975 10.2196/17831 10.1016/j.jad.2008.05.004 10.1111/pcn.13117 10.1097/00005650-199806000-00002 10.1016/j.jad.2017.07.044 10.1037/a0024512 10.1177/0272989X16656165 10.1097/MD.0000000000019148 10.1037/pst0000383 10.2196/mental.7785 10.1093/heapol/czw096 10.1002/mpr.1782 10.3390/ijerph17249308 10.1177/0272989X12455463 10.1007/s00127-015-1014-5 10.1016/j.janxdis.2021.102494 10.1186/s12889-016-3622-8 10.1002/mpr.1759 10.1371/journal.pone.0190554 10.1007/s11136-008-9406-6 10.1002/da.22778 10.1089/tmj.2015.0214 10.1521/pdps.2015.43.3.423 10.1016/j.ijmedinf.2020.104369 10.1007/s40258-016-0266-x 10.1037/abn0000362 10.15585/mmwr.mm6936a4 10.1002/wps.20610 10.2471/BLT.15.164418 10.1146/annurev-publhealth-032013-182435 10.1089/cyber.2009.0224 |
| ContentType | Journal Article |
| Copyright | COPYRIGHT 2022 Public Library of Science 2022 You et al. This is an open access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. 2022 You et al 2022 You et al |
| Copyright_xml | – notice: COPYRIGHT 2022 Public Library of Science – notice: 2022 You et al. This is an open access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. – notice: 2022 You et al 2022 You et al |
| DBID | AAYXX CITATION NPM IOV ISR 3V. 7QG 7QL 7QO 7RV 7SN 7SS 7T5 7TG 7TM 7U9 7X2 7X7 7XB 88E 8AO 8C1 8FD 8FE 8FG 8FH 8FI 8FJ 8FK ABJCF ABUWG AEUYN AFKRA ARAPS ATCPS AZQEC BBNVY BENPR BGLVJ BHPHI C1K CCPQU COVID D1I DWQXO FR3 FYUFA GHDGH GNUQQ H94 HCIFZ K9. KB. KB0 KL. L6V LK8 M0K M0S M1P M7N M7P M7S NAPCQ P5Z P62 P64 PATMY PDBOC PHGZM PHGZT PIMPY PJZUB PKEHL PPXIY PQEST PQGLB PQQKQ PQUKI PRINS PTHSS PYCSY RC3 7X8 5PM DOA |
| DOI | 10.1371/journal.pone.0268061 |
| DatabaseName | CrossRef PubMed Gale In Context Opposing Viewpoints Gale In Context Science ProQuest Central (Corporate) Animal Behavior Abstracts Bacteriology Abstracts (Microbiology B) Biotechnology Research Abstracts Nursing & Allied Health Database Ecology Abstracts Entomology Abstracts (Full archive) Immunology Abstracts Meteorological & Geoastrophysical Abstracts Nucleic Acids Abstracts Virology and AIDS Abstracts Agricultural Science Collection Health & Medical Collection ProQuest Central (purchase pre-March 2016) Medical Database (Alumni Edition) ProQuest Pharma Collection Public Health Database Technology Research Database ProQuest SciTech Collection ProQuest Technology Collection ProQuest Natural Science Collection ProQuest Hospital Collection Hospital Premium Collection (Alumni Edition) ProQuest Central (Alumni) (purchase pre-March 2016) Materials Science & Engineering Collection ProQuest Central (Alumni) ProQuest One Sustainability ProQuest Central UK/Ireland Advanced Technologies & Aerospace Collection Agricultural & Environmental Science Collection ProQuest Central Essentials Biological Science Collection ProQuest Central Technology Collection Natural Science Collection Environmental Sciences and Pollution Management ProQuest One Community College Coronavirus Research Database ProQuest Materials Science Collection ProQuest Central Engineering Research Database Health Research Premium Collection Health Research Premium Collection (Alumni) ProQuest Central Student AIDS and Cancer Research Abstracts SciTech Premium Collection ProQuest Health & Medical Complete (Alumni) Materials Science Database Nursing & Allied Health Database (Alumni Edition) Meteorological & Geoastrophysical Abstracts - Academic ProQuest Engineering Collection Biological Sciences Agriculture Science Database ProQuest Health & Medical Collection Medical Database Algology Mycology and Protozoology Abstracts (Microbiology C) ProQuest Biological Science Engineering Database Nursing & Allied Health Premium Advanced Technologies & Aerospace Database ProQuest Advanced Technologies & Aerospace Collection Biotechnology and BioEngineering Abstracts Environmental Science Database Materials Science Collection ProQuest Central Premium ProQuest One Academic Publicly Available Content Database ProQuest Health & Medical Research Collection ProQuest One Academic Middle East (New) ProQuest One Health & Nursing ProQuest One Academic Eastern Edition (DO NOT USE) ProQuest One Applied & Life Sciences ProQuest One Academic ProQuest One Academic UKI Edition ProQuest Central China Engineering Collection Environmental Science Collection Genetics Abstracts MEDLINE - Academic PubMed Central (Full Participant titles) DOAJ Directory of Open Access Journals |
| DatabaseTitle | CrossRef PubMed Agricultural Science Database Publicly Available Content Database ProQuest Central Student ProQuest Advanced Technologies & Aerospace Collection ProQuest Central Essentials Nucleic Acids Abstracts SciTech Premium Collection ProQuest Central China Environmental Sciences and Pollution Management ProQuest One Applied & Life Sciences ProQuest One Sustainability Health Research Premium Collection Meteorological & Geoastrophysical Abstracts Natural Science Collection Health & Medical Research Collection Biological Science Collection ProQuest Central (New) ProQuest Medical Library (Alumni) Engineering Collection Advanced Technologies & Aerospace Collection Engineering Database Virology and AIDS Abstracts ProQuest Biological Science Collection ProQuest One Academic Eastern Edition Agricultural Science Collection Coronavirus Research Database ProQuest Hospital Collection ProQuest Technology Collection Health Research Premium Collection (Alumni) Biological Science Database Ecology Abstracts ProQuest Hospital Collection (Alumni) Biotechnology and BioEngineering Abstracts Environmental Science Collection Entomology Abstracts Nursing & Allied Health Premium ProQuest Health & Medical Complete ProQuest One Academic UKI Edition Environmental Science Database ProQuest Nursing & Allied Health Source (Alumni) Engineering Research Database ProQuest One Academic Meteorological & Geoastrophysical Abstracts - Academic ProQuest One Academic (New) Technology Collection Technology Research Database ProQuest One Academic Middle East (New) Materials Science Collection ProQuest Health & Medical Complete (Alumni) ProQuest Central (Alumni Edition) ProQuest One Community College ProQuest One Health & Nursing ProQuest Natural Science Collection ProQuest Pharma Collection ProQuest Central ProQuest Health & Medical Research Collection Genetics Abstracts ProQuest Engineering Collection Biotechnology Research Abstracts Health and Medicine Complete (Alumni Edition) ProQuest Central Korea Bacteriology Abstracts (Microbiology B) Algology Mycology and Protozoology Abstracts (Microbiology C) Agricultural & Environmental Science Collection AIDS and Cancer Research Abstracts Materials Science Database ProQuest Materials Science Collection ProQuest Public Health ProQuest Nursing & Allied Health Source ProQuest SciTech Collection Advanced Technologies & Aerospace Database ProQuest Medical Library Animal Behavior Abstracts Materials Science & Engineering Collection Immunology Abstracts ProQuest Central (Alumni) MEDLINE - Academic |
| DatabaseTitleList | MEDLINE - Academic Agricultural Science Database PubMed |
| Database_xml | – sequence: 1 dbid: DOA name: DOAJ Directory of Open Access Journals url: https://www.doaj.org/ sourceTypes: Open Website – sequence: 2 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 3 dbid: 8FG name: ProQuest Technology Collection url: https://search.proquest.com/technologycollection1 sourceTypes: Aggregation Database |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Sciences (General) |
| DocumentTitleAlternate | Cost-effectiveness analysis of i-CBT for anxiety |
| EISSN | 1932-6203 |
| ExternalDocumentID | 2686208991 oai_doaj_org_article_50018c1446674a14b8e7bc253c7a7dbc PMC9070891 A702605824 35511888 10_1371_journal_pone_0268061 |
| Genre | Journal Article |
| GeographicLocations | China Hong Kong China United States--US |
| GeographicLocations_xml | – name: China – name: Hong Kong China – name: United States--US |
| GrantInformation_xml | – fundername: ; grantid: 17180271 |
| GroupedDBID | --- 123 29O 2WC 53G 5VS 7RV 7X2 7X7 7XC 88E 8AO 8C1 8CJ 8FE 8FG 8FH 8FI 8FJ A8Z AAFWJ AAUCC AAWOE AAYXX ABDBF ABIVO ABJCF ABUWG ACGFO ACIHN ACIWK ACPRK ACUHS ADBBV AEAQA AENEX AEUYN AFKRA AFPKN AFRAH AHMBA ALIPV ALMA_UNASSIGNED_HOLDINGS AOIJS APEBS ARAPS ATCPS BAWUL BBNVY BCNDV BENPR BGLVJ BHPHI BKEYQ BPHCQ BVXVI BWKFM CCPQU CITATION CS3 D1I D1J D1K DIK DU5 E3Z EAP EAS EBD EMOBN ESX EX3 F5P FPL FYUFA GROUPED_DOAJ GX1 HCIFZ HH5 HMCUK HYE IAO IEA IGS IHR IHW INH INR IOV IPY ISE ISR ITC K6- KB. KQ8 L6V LK5 LK8 M0K M1P M48 M7P M7R M7S M~E NAPCQ O5R O5S OK1 OVT P2P P62 PATMY PDBOC PHGZM PHGZT PIMPY PQQKQ PROAC PSQYO PTHSS PV9 PYCSY RNS RPM RZL SV3 TR2 UKHRP WOQ WOW ~02 ~KM ADRAZ IPNFZ NPM PJZUB PPXIY PQGLB RIG BBORY PMFND 3V. 7QG 7QL 7QO 7SN 7SS 7T5 7TG 7TM 7U9 7XB 8FD 8FK AZQEC C1K COVID DWQXO FR3 GNUQQ H94 K9. KL. M7N P64 PKEHL PQEST PQUKI PRINS RC3 7X8 5PM PUEGO AAPBV ABPTK BBAFP N95 |
| ID | FETCH-LOGICAL-c692t-2f4a8616f5caa21644d4a6492ebf442f6eab595de625dd79e30d1ef6a6488bd73 |
| IEDL.DBID | M48 |
| ISSN | 1932-6203 |
| IngestDate | Mon Dec 05 23:08:03 EST 2022 Wed Aug 27 01:05:52 EDT 2025 Thu Aug 21 13:32:07 EDT 2025 Tue Aug 05 11:06:40 EDT 2025 Sat Aug 23 13:18:20 EDT 2025 Tue Jun 17 21:26:51 EDT 2025 Tue Jun 10 20:53:55 EDT 2025 Fri Jun 27 03:39:31 EDT 2025 Fri Jun 27 04:38:08 EDT 2025 Thu May 22 20:54:10 EDT 2025 Mon Jul 21 06:00:20 EDT 2025 Thu Apr 24 22:55:05 EDT 2025 Tue Jul 01 01:41:39 EDT 2025 |
| IsDoiOpenAccess | true |
| IsOpenAccess | true |
| IsPeerReviewed | true |
| IsScholarly | true |
| Issue | 5 |
| Language | English |
| License | This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Creative Commons Attribution License |
| LinkModel | DirectLink |
| MergedId | FETCHMERGED-LOGICAL-c692t-2f4a8616f5caa21644d4a6492ebf442f6eab595de625dd79e30d1ef6a6488bd73 |
| Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 14 content type line 23 Competing Interests: The authors have declared that no competing interests exist. |
| ORCID | 0000-0002-5763-7403 |
| OpenAccessLink | http://journals.scholarsportal.info/openUrl.xqy?doi=10.1371/journal.pone.0268061 |
| PMID | 35511888 |
| PQID | 2686208991 |
| PQPubID | 1436336 |
| PageCount | e0268061 |
| ParticipantIDs | plos_journals_2686208991 doaj_primary_oai_doaj_org_article_50018c1446674a14b8e7bc253c7a7dbc pubmedcentral_primary_oai_pubmedcentral_nih_gov_9070891 proquest_miscellaneous_2660100479 proquest_journals_2686208991 gale_infotracmisc_A702605824 gale_infotracacademiconefile_A702605824 gale_incontextgauss_ISR_A702605824 gale_incontextgauss_IOV_A702605824 gale_healthsolutions_A702605824 pubmed_primary_35511888 crossref_primary_10_1371_journal_pone_0268061 crossref_citationtrail_10_1371_journal_pone_0268061 |
| ProviderPackageCode | CITATION AAYXX |
| PublicationCentury | 2000 |
| PublicationDate | 2022-05-05 |
| PublicationDateYYYYMMDD | 2022-05-05 |
| PublicationDate_xml | – month: 05 year: 2022 text: 2022-05-05 day: 05 |
| PublicationDecade | 2020 |
| PublicationPlace | United States |
| PublicationPlace_xml | – name: United States – name: San Francisco – name: San Francisco, CA USA |
| PublicationTitle | PloS one |
| PublicationTitleAlternate | PLoS One |
| PublicationYear | 2022 |
| Publisher | Public Library of Science Public Library of Science (PLoS) |
| Publisher_xml | – name: Public Library of Science – name: Public Library of Science (PLoS) |
| References | KK Fitzpatrick (pone.0268061.ref048) 2017; 4 B Draper (pone.0268061.ref031) 2009; 113 J Chhatwal (pone.0268061.ref034) 2016; 36 S Guo (pone.0268061.ref044) 2020; 99 W Xiong (pone.0268061.ref045) 2016; 28 M Harrer (pone.0268061.ref011) 2019; 28 TMH Li (pone.0268061.ref040) 2020; 74 X Wu (pone.0268061.ref039) 2021; 23 A Berger (pone.0268061.ref023) 2012; 12 MY Bertram (pone.0268061.ref050) 2016; 94 MJ Sharrock (pone.0268061.ref046) 2021; 84 pone.0268061.ref010 LC Lam (pone.0268061.ref008) 2015; 50 RP Auerbach (pone.0268061.ref001) 2018; 127 E Goldmann (pone.0268061.ref041) 2014; 35 G Marques (pone.0268061.ref037) 2021; 147 S Kumar (pone.0268061.ref022) 2018; 13 SM Meier (pone.0268061.ref024) 2016; 209 C Christ (pone.0268061.ref018) 2020; 22 DD Ebert (pone.0268061.ref006) 2019; 28 WW Mak (pone.0268061.ref012) 2017; 19 Lo AP Powell CLYM (pone.0268061.ref019) 2021; 13 CK Wong (pone.0268061.ref051) 2016; 14 MR Gold (pone.0268061.ref028) 1998; 36 G Andersson (pone.0268061.ref014) 2008; 26 G Andersson (pone.0268061.ref021) 2019; 18 pone.0268061.ref026 SH Spence (pone.0268061.ref017) 2011; 79 A Lungu (pone.0268061.ref015) 2016; 22 Health Quality Ontario (pone.0268061.ref020) 2019; 19 E Shirneshan (pone.0268061.ref005) 2013; 27 MG Newman (pone.0268061.ref047) 2021; 58 E Axelsson (pone.0268061.ref029) 2020; 77 MÉ Czeisler (pone.0268061.ref042) 2020; 69 U Siebert (pone.0268061.ref013) 2012; 32 DA Revicki (pone.0268061.ref027) 2008; 17 pone.0268061.ref032 KK Hung (pone.0268061.ref043) 2020 C Botella (pone.0268061.ref016) 2010; 13 pone.0268061.ref030 Y Sun (pone.0268061.ref038) 2020; 17 pone.0268061.ref036 pone.0268061.ref033 R Bruffaerts (pone.0268061.ref002) 2018; 225 LA Robinson (pone.0268061.ref049) 2017; 32 N Thoma (pone.0268061.ref009) 2015; 43 World Health Organization (pone.0268061.ref035) 2002 CF Hjorth (pone.0268061.ref003) 2016; 16 KW Lun (pone.0268061.ref007) 2018; 24 J Alonso (pone.0268061.ref004) 2018; 35 pone.0268061.ref025 |
| References_xml | – volume: 19 start-page: e84 issue: 3 year: 2017 ident: pone.0268061.ref012 article-title: The efficacy of internet-based mindfulness training and cognitive-behavioral training with telephone support in the enhancement of mental health among college students and young working adults: randomized controlled trial. publication-title: J Med Internet Res doi: 10.2196/jmir.6737 – ident: pone.0268061.ref030 – volume: 19 start-page: 1 issue: 6 year: 2019 ident: pone.0268061.ref020 article-title: Internet-delivered cognitive behavioural therapy for major depression and anxiety disorders: a health technology assessment. publication-title: Ont Health Technol Assess Ser. – volume: 77 start-page: 915 issue: 9 year: 2020 ident: pone.0268061.ref029 article-title: Effect of internet vs face-to-face cognitive behavior therapy for health anxiety: a randomized noninferiority clinical trial. publication-title: JAMA Psychiatry doi: 10.1001/jamapsychiatry.2020.0940 – volume: 12 start-page: 177 year: 2012 ident: pone.0268061.ref023 article-title: Change in healthcare utilization and costs following initiation of benzodiazepine therapy for long-term treatment of generalized anxiety disorder: a retrospective cohort study. publication-title: BMC Psychiatry. doi: 10.1186/1471-244X-12-177 – volume: 23 start-page: e23126 issue: 1 year: 2021 ident: pone.0268061.ref039 article-title: Geographic distribution of mental health problems among Chinese college students during the COVID-19 pandemic: nationwide, web-based survey study publication-title: J Med Internet Res doi: 10.2196/23126 – volume: 27 start-page: 720 issue: 7 year: 2013 ident: pone.0268061.ref005 article-title: Incremental direct medical expenditures associated with anxiety disorders for the U.S. adult population: evidence from the Medical Expenditure Panel Survey. publication-title: J Anxiety Disord. doi: 10.1016/j.janxdis.2013.09.009 – ident: pone.0268061.ref010 – volume: 209 start-page: 216 issue: 3 year: 2016 ident: pone.0268061.ref024 article-title: Increased mortality among people with anxiety disorders: total population study. publication-title: Br J Psychiatry. doi: 10.1192/bjp.bp.115.171975 – volume: 22 start-page: e17831 issue: 9 year: 2020 ident: pone.0268061.ref018 article-title: Internet and computer-based cognitive behavioral therapy for anxiety and depression in adolescents and young adults: systematic review and meta-analysis. publication-title: J Med Internet Res doi: 10.2196/17831 – volume: 113 start-page: 195 issue: 1–2 year: 2009 ident: pone.0268061.ref031 article-title: Patterns of hospitalisation for depressive and anxiety disorders across the lifespan in Australia publication-title: J Affect Disord doi: 10.1016/j.jad.2008.05.004 – volume: 74 start-page: 564 issue: 10 year: 2020 ident: pone.0268061.ref040 article-title: Exploring student mental health and intention to use online counseling in Hong Kong during the COVID-19 pandemic. publication-title: Psychiatry Clin Neurosci. doi: 10.1111/pcn.13117 – volume: 36 start-page: 778 issue: 6 year: 1998 ident: pone.0268061.ref028 article-title: Toward consistency in cost-utility analyses: using national measures to create condition-specific values. publication-title: Med Care doi: 10.1097/00005650-199806000-00002 – volume: 225 start-page: 97 year: 2018 ident: pone.0268061.ref002 article-title: Mental health problems in college freshmen: Prevalence and academic functioning publication-title: J Affect Disord doi: 10.1016/j.jad.2017.07.044 – volume: 79 start-page: 629 issue: 5 year: 2011 ident: pone.0268061.ref017 article-title: A randomized controlled trial of online versus clinic-based CBT for adolescent anxiety. publication-title: J Consult Clin Psychol. doi: 10.1037/a0024512 – volume: 36 start-page: 952 issue: 8 year: 2016 ident: pone.0268061.ref034 article-title: Changing cycle lengths in state-transition models: challenges and solutions. publication-title: Med Decis Making. doi: 10.1177/0272989X16656165 – ident: pone.0268061.ref033 – volume: 99 start-page: e19148 issue: 7 year: 2020 ident: pone.0268061.ref044 article-title: The awareness rate of mental health knowledge Among Chinese adolescent: A systematic review and meta-analysis. publication-title: Medicine (Baltimore). doi: 10.1097/MD.0000000000019148 – volume: 58 start-page: 591 issue: 4 year: 2021 ident: pone.0268061.ref047 article-title: A randomized controlled feasibility trial of internet-delivered guided self-help for generalized anxiety disorder (GAD) among university students in India. publication-title: Psychotherapy (Chic). doi: 10.1037/pst0000383 – volume: 4 start-page: e19 issue: 2 year: 2017 ident: pone.0268061.ref048 article-title: Delivering Cognitive Behavior Therapy to Young Adults With Symptoms of Depression and Anxiety Using a Fully Automated Conversational Agent (Woebot): A Randomized Controlled Trial. publication-title: JMIR Ment Health. doi: 10.2196/mental.7785 – volume: 32 start-page: 141 issue: 1 year: 2017 ident: pone.0268061.ref049 article-title: Understanding and improving the one and three times GDP per capita cost-effectiveness thresholds. publication-title: Health Policy Plan. doi: 10.1093/heapol/czw096 – volume: 28 start-page: e1782 issue: 2 year: 2019 ident: pone.0268061.ref006 article-title: Barriers of mental health treatment utilization among first-year college students: First cross-national results from the WHO World Mental Health International College Student Initiative. publication-title: Int J Methods Psychiatr Res. doi: 10.1002/mpr.1782 – volume: 17 start-page: 9308 issue: 24 year: 2020 ident: pone.0268061.ref038 article-title: University students’ perceived peer support and experienced depressive symptoms during the COVID-19 pandemic: the mediating role of emotional well-being publication-title: Int J Environ Res Public Health doi: 10.3390/ijerph17249308 – volume-title: The World health report 2002: Reducing risks, promoting healthy life. year: 2002 ident: pone.0268061.ref035 – volume: 32 start-page: 690 issue: 5 year: 2012 ident: pone.0268061.ref013 article-title: State-transition modeling: a report of the ISPOR-SMDM Modeling Good Research Practices Task Force-3. publication-title: Med Decis Making. doi: 10.1177/0272989X12455463 – volume: 50 start-page: 1379 issue: 9 year: 2015 ident: pone.0268061.ref008 article-title: Prevalence, psychosocial correlates and service utilization of depressive and anxiety disorders in Hong Kong: the Hong Kong Mental Morbidity Survey (HKMMS). publication-title: Soc Psychiatry Psychiatr Epidemiol. doi: 10.1007/s00127-015-1014-5 – volume: 84 start-page: 102494 year: 2021 ident: pone.0268061.ref046 article-title: The uptake and outcomes of Internet-based cognitive behavioural therapy for health anxiety symptoms during the COVID-19 pandemic. publication-title: J Anxiety Disord. doi: 10.1016/j.janxdis.2021.102494 – ident: pone.0268061.ref032 – volume: 16 start-page: 976 year: 2016 ident: pone.0268061.ref003 article-title: Mental health and school dropout across educational levels and genders: a 4.8-year follow-up study. publication-title: BMC Public Health. doi: 10.1186/s12889-016-3622-8 – ident: pone.0268061.ref026 – volume: 28 start-page: e1759 issue: 2 year: 2019 ident: pone.0268061.ref011 article-title: Internet interventions for mental health in university students: A systematic review and meta-analysis. publication-title: Int J Methods Psychiatr Res doi: 10.1002/mpr.1759 – volume: 13 start-page: e0190554 issue: 1 year: 2018 ident: pone.0268061.ref022 article-title: Mobile and traditional cognitive behavioral therapy programs for generalized anxiety disorder: a cost-effectiveness analysis. publication-title: PLoS One. doi: 10.1371/journal.pone.0190554 – volume: 17 start-page: 1285 issue: 10 year: 2008 ident: pone.0268061.ref027 article-title: Health-related quality of life and utilities in primary-care patients with generalized anxiety disorder. publication-title: Qual Life Res. doi: 10.1007/s11136-008-9406-6 – volume: 24 start-page: 466 issue: 5 year: 2018 ident: pone.0268061.ref007 article-title: Depression and anxiety among university students in Hong Kong. publication-title: Hong Kong Med J. – volume: 35 start-page: 802 issue: 9 year: 2018 ident: pone.0268061.ref004 article-title: Severe role impairment associated with mental disorders: Results of the WHO World Mental Health Surveys International College Student Project. publication-title: Depress Anxiety. doi: 10.1002/da.22778 – volume: 22 start-page: 991 issue: 12 year: 2016 ident: pone.0268061.ref015 article-title: Time for a change: college students’ preference for technology-mediated versus face-to-face help for emotional distress. publication-title: Telemed J E Health. doi: 10.1089/tmj.2015.0214 – volume: 43 start-page: 423 issue: 3 year: 2015 ident: pone.0268061.ref009 article-title: Contemporary cognitive behavior therapy: a review of theory, history, and evidence. publication-title: Psychodyn Psychiatry. doi: 10.1521/pdps.2015.43.3.423 – volume: 147 start-page: 104369 year: 2021 ident: pone.0268061.ref037 article-title: Impact of COVID-19 on the psychological health of university students in Spain and their attitudes toward mobile mental health solutions. publication-title: Int J Med Inform. doi: 10.1016/j.ijmedinf.2020.104369 – volume: 14 start-page: 647 issue: 6 year: 2016 ident: pone.0268061.ref051 article-title: Possible Impact of Incremental Cost-Effectiveness Ratio (ICER) on Decision Making for Cancer Screening in Hong Kong: A Systematic Review. publication-title: Appl Health Econ Health Policy doi: 10.1007/s40258-016-0266-x – volume: 127 start-page: 623 issue: 7 year: 2018 ident: pone.0268061.ref001 article-title: WHO World Mental Health Surveys International College Student Project: Prevalence and distribution of mental disorders. publication-title: J Abnorm Psychol. doi: 10.1037/abn0000362 – ident: pone.0268061.ref025 – volume: 69 start-page: 1250 issue: 36 year: 2020 ident: pone.0268061.ref042 article-title: Delay or avoidance of medical care because of COVID-19-related concerns–United States, June 2020. publication-title: MMWR Morb Mortal Wkly Rep doi: 10.15585/mmwr.mm6936a4 – volume: 18 start-page: 20 issue: 1 year: 2019 ident: pone.0268061.ref021 article-title: Internet-delivered psychological treatments: from innovation to implementation. publication-title: World Psychiatry. doi: 10.1002/wps.20610 – volume: 94 start-page: 925 issue: 12 year: 2016 ident: pone.0268061.ref050 article-title: Cost-effectiveness thresholds: pros and cons publication-title: Bull World Health Organ doi: 10.2471/BLT.15.164418 – volume: 35 start-page: 169 year: 2014 ident: pone.0268061.ref041 article-title: Mental health consequences of disasters. publication-title: Annu Rev Public Health doi: 10.1146/annurev-publhealth-032013-182435 – volume: 13 start-page: 1 year: 2021 ident: pone.0268061.ref019 article-title: A pilot study on the effectiveness of low-intensity cognitive behavioural therapy (LiCBT) for common mental disorders in Hong Kong. publication-title: Behav Cogn Psychother. – volume: 13 start-page: 407 issue: 4 year: 2010 ident: pone.0268061.ref016 article-title: An internet-based self-help treatment for fear of public speaking: a controlled trial. publication-title: Cyberpsychol Behav Soc Netw. doi: 10.1089/cyber.2009.0224 – ident: pone.0268061.ref036 – volume: 26 start-page: 2 year: 2008 ident: pone.0268061.ref014 publication-title: Development of a New Approach to Guided Self-Help via the Internet: The Swedish Experience, Journal of Technology in Human Services. – year: 2020 ident: pone.0268061.ref043 article-title: Health service utilization in Hong Kong during the COVID-19 pandemic–a cross-sectional public survey publication-title: Int J Health Policy Manag – volume: 28 start-page: 4 issue: 1 year: 2016 ident: pone.0268061.ref045 article-title: Translated and annotated version of the 2015–2020 National Mental Health Work Plan of the People’s Republic of China. publication-title: Shanghai Arch Psychiatry |
| SSID | ssj0053866 |
| Score | 2.455169 |
| Snippet | High prevalence of anxiety symptoms has been reported globally in the university students. Cognitive behavioral therapy (CBT) is the recognized treatment for... Background and aim High prevalence of anxiety symptoms has been reported globally in the university students. Cognitive behavioral therapy (CBT) is the... Background and aimHigh prevalence of anxiety symptoms has been reported globally in the university students. Cognitive behavioral therapy (CBT) is the... Background and aim High prevalence of anxiety symptoms has been reported globally in the university students. Cognitive behavioral therapy (CBT) is the... |
| SourceID | plos doaj pubmedcentral proquest gale pubmed crossref |
| SourceType | Open Website Open Access Repository Aggregation Database Index Database Enrichment Source |
| StartPage | e0268061 |
| SubjectTerms | Age Anxiety Anxiety disorders Behavior modification Biology and Life Sciences Care and treatment Clinical trials Cognitive ability Cognitive behavioral therapy Cognitive therapy College students Complications and side effects Computer and Information Sciences Cost analysis Cost benefit analysis Diagnosis Evaluation Generalized anxiety disorder Health surveys Internet Intervention Markov chains Medicine and Health Sciences Mental disorders Mental health Modelling Mortality Patient outcomes People and places Psychological aspects Remission (Medicine) Sensitivity analysis Social Sciences Statistical analysis Students Systematic review University students |
| SummonAdditionalLinks | – databaseName: DOAJ Directory of Open Access Journals dbid: DOA link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwrV1Lb9QwELbQnrggyquBBQxCAg5uN4lf4bZUVAUJkICi3iK_Uiq1yQpnEf0P_Gg8sTc0qFI5cF1_We3OjMczzsw3CD3TuWwWuuTElMwQqoUh2lBNGJeVtMJIruBC__0HfnBI3x2xowujvqAmLNIDR8HtMhgbZyBr4YKqnGrphDYFK41QwmoD3jeceZtkKvrgsIs5T41ypch3k152Vl3rdkLWIRc8nxxEA1__6JVnq9POXxZy_l05eeEo2r-JbqQYEi_jb99C11x7C22lXerxi0Ql_fI2-rXX-Z7Emo3k1nDX4JPhGtD1xK9XA7G5xWMZEf7TuI9jc9Y5DoEtXo8VHNhHPkyP4RIXq_Yn1H1if3626rsz_wovMXQAdT_IMGYnACLvyR10uP_my94BSfMXiOFV0ZOioUrynDfMKFWEvIpaqjitCqcbSouGO6VZxawLOZS1onLlwuau4QEjpbaivItmbZD4NsKqErbSQftGaJrbEljAQrCom4ppHdxAhsqNMmqTyMlhRsZpPbxxEyFJibKtQYV1UmGGyPjUKpJzXIF_DXoesUCtPXwQDK5OBldfZXAZegxWUsc-1dFB1EsB9GxMFjRDTwcE0Gu0UL9zrNbe128_fv0H0OdPE9DzBGq6IA6jUs9E-E9A2zVBzifI4CTMZHkbbHojFV8X0BkEr3yDUOYbO798-cm4DF8KNXmt69aAgWQeRhRk6F7cFqNkQxQbMlcpMyQmG2Yi-ulKe_JtYDevwiEkq_z-_9DVA3S9gHYVKFBlczTrv6_dwxBE9vrR4C9-AwZTc9Q priority: 102 providerName: Directory of Open Access Journals – databaseName: Public Health Database dbid: 8C1 link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwjV1Lb9QwELZguXBBlFcDBQxCAg5uN4lf4YKWFVVBAiSgqLfIr5RKbRLqLKL_gR-NJ_GmBFXAdf1ltTvjmczYM98g9ESnsprrnBOTM0OoFoZoQzVhXBbSCiO5ggP9d-_53j59e8AO4oGbj2WVa5_YO2rbGDgj38mglQHuqNKX7TcCU6PgdjWO0LiMrqTBBwN3vlyOJR7BljmP7XK5SHeidrbbpnbbIfeQc55OXkc9a__om2ftceMvCjz_rJ_87YW0ex1di5EkXgyq30CXXH0DbURb9fhZJJR-fhP9XDa-I0PlRnRuuKnwUX8Y6DriV21Pb27xWEyEz9v38dCidYZDeItXYx0H9gMrpsdwlItV_QOqP7E_O2m75sS_wAsMfUDNd9IP2wmAgf3kFtrfff15uUfiFAZieJF1JKuokjzlFTNKZSG7opYqTovM6YrSrOJOaVYw60ImZa0oXD63qat4wEiprchvo1kdJL6JsCqELXTYA0ZomtocuMBCyKirgmkdnEGC8rUyShMpymFSxnHZ37uJkKoMsi1BhWVUYYLI-FQ7UHT8A_8K9DxigWC7_6A5PSyjvZYMphUaSJa5oCqlWjqhTcZyI5Sw2iToIeyScuhWHd1EuRBA0sZkRhP0uEcAyUYNVTyHauV9-ebDl_8Affo4AT2NoKoJ4jAqdk6E_wTkXRPk1gQZXIWZLG_Cnl5LxZfnRhWeXO_zi5cfjcvwpVCZV7tmBRhI6WFQQYLuDGYxSjbEsiF_lTJBYmIwE9FPV-qjrz3HeRFeRbJI7_79Z91DVzNoR4ECVLaFZt3pyt0PQWKnH_Se4BfuF2uF priority: 102 providerName: ProQuest |
| Title | Cost-effectiveness of internet-supported cognitive behavioral therapy for university students with anxiety symptoms: A Markov-model analysis |
| URI | https://www.ncbi.nlm.nih.gov/pubmed/35511888 https://www.proquest.com/docview/2686208991 https://www.proquest.com/docview/2660100479 https://pubmed.ncbi.nlm.nih.gov/PMC9070891 https://doaj.org/article/50018c1446674a14b8e7bc253c7a7dbc http://dx.doi.org/10.1371/journal.pone.0268061 |
| Volume | 17 |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwjV3fb9MwELZG98ILYvxaoBSDkICHVE3i2A4SQl21MZA20KCob5HtJGNSl5Q6Rev_wB-Nz3EDQUXsJQ_1l0g9-8539t13CD2XAS9GMqK-imLlE8mULxWRfkx5wjOmOBVwoH9ySo-n5MMsnu2gTc9WJ0C9NbSDflLT5Xx49X391ij8G9u1gQWbl4aLqsyHJqbgI4iHds3exKCZwwlp7xWMdtvbS_BafBqOIldM96-vdDYry-nfWu7eYl7pbW7p39mVf2xXR7fRLedn4nGzMPbQTl7eQXtOkzV-6eimX91FPyeVrv0mr8OZPlwV-MIeFea1r1cLS36e4TbVCP8u7sdNAdcaG-cXr9osD6wbzkyN4aAXi_IKckOxXl8u6upSv8ZjDFVC1Q_ftuIxgIYb5R6aHh1-mRz7rkeDr2gS1n5YEMFpQItYCRGa2ItkRFCShLksCAkLmgsZJ3GWmzgry1iSR6MsyAtqMJzLjEX3Ua80Et9HWCQsS6RZIYpJEmQRMIUZh1IWSSylMRUeijaTkSpHYA59NOapvZVjJpBpZJvCFKZuCj3kt28tGgKP_-APYJ5bLNBv2x-q5XnqtDmNoZehglCaMiICInnOpArjSDHBMqk89ARWSdrUsrZGJB0zoHCLeUg89MwigIKjhByfc7HSOn3_8es1QJ_POqAXDlRURhxKuLoK85-A2quD7HeQxpCozvA-rOmNVHQaQvUQXAsbofQ363z78NN2GD4KeXtlXq0AAwE_tDHw0INGLVrJGk_XRLece4h1FKYj-u5IefHNMqAnZqPiSfDw2n_9EboZQt0KZKrGfdSrl6v8sfEmazlAN9iMmSefBPA8ejdAuweHp5_OBvZ8ZmANyC9konyc |
| linkProvider | Scholars Portal |
| linkToHtml | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwtV1Lb9QwELbKcoALorwaKNQgEHBwu0kc20FCaFmouvSBBG3VW4gfKZXaJDRZYP8Dv4XfiCfxpgRVwKXX9STKzozHM-OZbxB6LH2RDWXIiAojRajkikhFJYmYiIXmSrAUEvrbO2xjj747iA4W0M95LwyUVc5tYmOodaEgR74WQCsD3FH5r8ovBKZGwe3qfIRGqxabZvbNhmzVy8kbK98nQbD-dne8QdxUAaJYHNQkyGgqmM-ySKVpYKMFqmnKaBwYmVEaZMykMoojbWxkoDWPTTjUvsmYpRFCah7a915Cl2kYcsDqF-OupMTaDsZce17I_TWnDatlkZtVG-uIIfN7x18zJaA7CwblcVGd5-j-Wa_52wG4fh1dc54rHrWqtogWTH4DLTrbUOFnDsD6-U30Y1xUNWkrRZwxxUWGj5rko6lJNS0bOHWNu-IlfAYXgNuWsBm27jSednUjuGpROCsMqWOc5t-h2hRXs5OyLk6qF3iEoe-o-Eqa4T6WoEVbuYX2LkQ-t9EgtxxfQjiNuY6l1TnFJfV1CNhj1kWVWRxJaY2Ph8K5MBLlINFhMsdx0tzzcRsatbxNQISJE6GHSPdU2UKC_IP-Nci5owVA7-aH4vQwcfYhiWA6ooLgnHGa-lQKw6UKolDxlGupPLQCWpK03bGdWUpGHEDhIhFQDz1qKADUI4eqocN0WlXJ5P3-fxB9_NAjeuqIssKyQ6WuU8P-JwAL61Eu9yitaVK95SXQ6TlXquRsE9sn53p-_vLDbhleCpWAuSmmQAMpBBiM4KE77bboOGt9ZxsvC-Eh3tswPdb3V_Kjzw2memyPPhH7d__-WSvoysbu9layNdnZvIeuBtAKA8Wv0TIa1KdTc986qLV80FgFjD5dtBn6BbFJqR8 |
| linkToPdf | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwtV3NbtQwELbKIiEuiPLXQKEGgYCDu5vEsR0khJaWVUuhIKBobyF2klKpTZYmC-w78EQ8HTOJkxJUAZde15MoOzP-7LFnviHkvnZVNtK-YMYPDONaGqYN1ywQKlSJNErEeKD_elds7fGX02C6RH62tTCYVtliYg3USWHwjHzoYSkD3lG5w8ymRbzdnDybfWHYQQpvWtt2Go2L7KSLbxC-lU-3N8HWDzxv8uLDxhazHQaYEaFXMS_jsRKuyAITxx5EDjzhseChl-qMcy8TaayDMEhSiBKSRIapP0rcNBMgo5ROpA_vPUfOSx-WTZhLctoFe4AjQthSPV-6Q-sZ67MiT9ch7lEj4faWwrpjQLcuDGaHRXnapvfP3M3fFsPJZXLJ7mLpuHG7ZbKU5lfIssWJkj6yZNaPr5IfG0VZsSZrxAIrLTJ6UB9EphUr57OaWj2hXSITPaEOoE152ILC1prOuxwSWjaMnCXFY2Qa598x85SWi6NZVRyVT-iYYg1S8ZXVjX5AoGFeuUb2zsQ-18kgB42vEBqHMgk1-J-RmruJjzxksF3VWRhoDUDkEL81RmQsPTp26TiM6js_CWFSo9sITRhZEzqEdU_NGnqQf8g_Rzt3skjuXf9QHO9HFiuiADslGgzUheSxy7VKpTZe4BsZy0Qbh6yhl0RNpWwHUdFYIkFcoDzukHu1BBJ85DhV9uN5WUbbbz7-h9D7dz2hh1YoK0AdJrZVG_CfkDisJ7nakwSYMr3hFfTpVitldDKh4cnWz08fvtsN40sxKzBPiznK4HECNklwyI1mWnSahX00xM5KOUT2JkxP9f2R_OBzza8ewjKoQvfm3z9rjVwAAIpebe_u3CIXPayKwTzYYJUMquN5ehv2qpW-U4MCJZ_OGoV-AcavrYE |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Cost-effectiveness+of+internet-supported+cognitive+behavioral+therapy+for+university+students+with+anxiety+symptoms%3A+A+Markov-model+analysis&rft.jtitle=PloS+one&rft.au=You%2C+Joyce+H.+S&rft.au=Luk%2C+Scotty+W.+C&rft.au=Chow%2C+Dilys+Y.+W&rft.au=Jiang%2C+Xinchan&rft.date=2022-05-05&rft.pub=Public+Library+of+Science&rft.issn=1932-6203&rft.eissn=1932-6203&rft.volume=17&rft.issue=5&rft.spage=e0268061&rft_id=info:doi/10.1371%2Fjournal.pone.0268061&rft.externalDocID=A702605824 |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=1932-6203&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=1932-6203&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=1932-6203&client=summon |