Comparative analysis of the vaginal microbiome of pregnant women with either Trichomonas vaginalis or Chlamydia trachomatis

• Published in: PloS one Vol. 14; no. 12; p. e0225545
• Main Authors: Masha, Simon Chengo, Owuor, Collins, Ngoi, Joyce Mwongeli, Cools, Piet, Sanders, Eduard J, Vaneechoutte, Mario, Crucitti, Tania, de Villiers, Etienne P
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 12.12.2019; Public Library of Science (PLoS)
• Subjects: Abundance; Adolescent; Adult; Arthritis; Bacteria; Bacterial vaginosis; Bacteriology; Biodiversity; Biology and Life Sciences; Chlamydia; Chlamydia Infections - immunology; Chlamydia Infections - microbiology; Chlamydia trachomatis; Chlamydia trachomatis - genetics; Chlamydia trachomatis - immunology; Chlamydia trachomatis - isolation & purification; Comparative analysis; Composition; Deoxyribonucleic acid; Disease transmission; DNA; DNA, Bacterial - isolation & purification; Ecology and Environmental Sciences; Female; Future predictions; Genes; Health; Health sciences; Hospitals; Humans; Infection; Infections; Laboratories; Medicine; Medicine and Health Sciences; Microbiomes; Microbiota - genetics; Microbiota - immunology; Next-generation sequencing; Parasitic diseases; Pathogenic microorganisms; Pathogens; Pregnancy; Pregnancy Complications, Infectious - immunology; Pregnancy Complications, Infectious - microbiology; Pregnant women; Premature birth; Prenatal care; Ribosomal RNA; RNA; RNA, Ribosomal, 16S - genetics; rRNA 16S; Sexually transmitted diseases; Software industry; STD; Trichomonas vaginalis; Trichomonas vaginalis - genetics; Trichomonas vaginalis - immunology; Trichomonas vaginalis - isolation & purification; Trichomonas Vaginitis - immunology; Trichomonas Vaginitis - microbiology; Vagina; Vagina - microbiology; Vaginosis; Womens health; Young Adult; Kenya; United States; United Kingdom > UK; Belgium

Although the significance of the human vaginal microbiome for health and disease is increasingly acknowledged, there is paucity of data on the differences in the composition of the vaginal microbiome upon infection with different sexually transmitted pathogens. The composition of the vaginal bacteri...