High SLC2A1 expression associated with suppressing CD8 T cells and B cells promoted cancer survival in gastric cancer

• Published in: PloS one Vol. 16; no. 3; p. e0245075
• Main Authors: Min, Kyueng-Whan, Kim, Dong-Hoon, Son, Byoung Kwan, Moon, Kyoung Min, Kim, So Myoung, Intazur Rahaman, Md, Kim, So Won, Kim, Eun-Kyung, Kwon, Mi Jung, Koh, Young Wha, Oh, Il Hwan
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 18.03.2021; Public Library of Science (PLoS)
• Subjects: Analysis; B cells; Biology and Life Sciences; Cancer; CD8 antigen; Cell proliferation; Cell survival; Clinical outcomes; Cloning; Epstein-Barr virus; ErbB-2 protein; Gastric cancer; Gene expression; Genetic aspects; Genomes; Glucose; Glycolysis; Health care facilities; Hospitals; Internal medicine; Lymphocytes; Lymphocytes B; Lymphocytes T; Medical prognosis; Medical records; Medical schools; Medicine; Medicine and Health Sciences; Metabolism; Methodology; Oxidative phosphorylation; Pathology; PD-L1 protein; Pharmacology; Phosphorylation; Physical Sciences; Stomach cancer; T cells; Tumor cells; Tumors; South Korea; United Kingdom > UK; United States > US

High expression of glucose transporter family members, which augment glucose uptake and glycolytic flux, has been shown to play a pivotal role in the proliferation and survival of tumor cells, contributing to the energy supply, biosynthesis and homeostasis of cancer cells. Among the many members, so...