When drug treatments bias genetic studies: Mediation and interaction - Schmidt, Amand F.; Heerspink, Hiddo J. L.; Denig, Petra; Finan, Chris; Groenwold, Rolf H. H. (PloS one, 2019)
Keywords: Accounting; Bias; Biology and Life Sciences; Blood pressure; Cardiovascular disease; Computer Simulation; Confidence intervals; Consortia; Diabetes; Drug interactions; Drug Prescriptions; Drug therapy; Engineering and Technology; Estimates; Genes; Genetic analysis; Genetic aspects; Genetic Diseases, Inborn - drug therapy; Genetic Diseases, Inborn - epidemiology; Genetic Diseases, Inborn - genetics; Genetic diversity; Genetic effects; Genetic research; Genetic variance; Genetics; Genome-Wide Association Study; Genomes; Genotype & phenotype; Graph theory; Heart; Humans; Longitude; Mediation; Medical treatment; Medicine and Health Sciences; Negotiating; Pharmacogenomic Variants - genetics; Pharmacy; Phenotype; Phenotypes; Physiological aspects; Quantitative trait loci; Quantitative Trait Loci - genetics; Regression analysis; Rejection rate; Research and Analysis Methods; Root-mean-square errors; Studies; Trajectory analysis; Type 2 diabetes; United Kingdom; United Kingdom--UK; England; Netherlands