Urgent ultrasound guided hemodynamic assessments by a pediatric medical emergency team: a pilot study

To determine the feasibility of using the Ultrasound Cardiac Output Monitor (USCOM) as an adjunct during hemodynamic assessments by a pediatric medical emergency team (PMET). Pediatric in-patients at McMaster Children's Hospital aged under 18 years requiring urgent PMET consultation, were eligi...

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Published inPloS one Vol. 8; no. 6; p. e66951
Main Authors Zorko, David J, Choong, Karen, Gilleland, Jonathan, Agar, Barbara, Baker, Shawn, Brennan, Cindy, Pullenayegum, Eleanor
Format Journal Article
LanguageEnglish
Published United States Public Library of Science 25.06.2013
Public Library of Science (PLoS)
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Summary:To determine the feasibility of using the Ultrasound Cardiac Output Monitor (USCOM) as an adjunct during hemodynamic assessments by a pediatric medical emergency team (PMET). Pediatric in-patients at McMaster Children's Hospital aged under 18 years requiring urgent PMET consultation, were eligible. Patients with known cardiac outflow valve defects, Pediatric Critical Care Unit in-patients, and those in cardiorespiratory arrest, were excluded. The primary outcome was feasibility, and the ease of USCOM transport and application as assessed by a self-administered user questionnaire. Secondary outcomes included the quality of USCOM measurements, and agreement in clinical versus USCOM-derived assessments. Forty-one patients from 85 eligible PMET consultations were enrolled between March and August 2011. A total of 55 USCOM assessments were performed on 36 of 41 (87.8%) participants. USCOM could not be completed in 5 (12.2%) participants due to patient agitation (n = 4) and emergent care (n = 1). USCOM was reported as easy to transport and apply by 97.4% and 94.7% of respondents respectively, not obstructive to patient care by 94.7%, and yielded timely measurements by 84.2% respondents. USCOM tracings were of good quality in 41 (75.9%) assessments. Agreement between clinical and USCOM-derived hemodynamic assessments by two independent raters was poor (Rater 1: κ = 0.094; Rater 2: κ = 0.146). USCOM can be applied by a PMET during urgent hemodynamic assessments in children. While USCOM has been validated in stable children, its role in guiding hemodynamic resuscitation and informing therapeutic goals in a hemodynamically unstable pediatric population requires further investigation.
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Competing Interests: There are no potential conflicts of interest relevant to subject of this manuscript. This is an investigator-initiated project. USCOM Limited provided the ultrasound cardiac output monitoring device for the duration of the project and financial support for the statistical analysis, which was conducted at McMaster University. USCOM Limited has no intellectual property of the design, execution, analysis, interpretation, and reporting of the results, or manuscript preparation for this study.
Conceived and designed the experiments: KC DZ JG EP. Performed the experiments: DZ KC JG BA SB CB. Analyzed the data: DZ KC JG EP. Contributed reagents/materials/analysis tools: DZ KC JG EP. Wrote the paper: DZ KC. Review and approval of final manuscript: JG EP CB BA SB DZ KC.
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0066951