TMS Enhances Retention of a Motor Skill in Parkinson's Disease

• Published in: Brain stimulation Vol. 8; no. 2; pp. 224 - 230
• Main Authors: Moisello, Clara, Blanco, Daniella, Fontanesi, Cecilia, Lin, Jing, Biagioni, Milton, Kumar, Pawan, Brys, Miroslaw, Loggini, Andrea, Marinelli, Lucio, Abbruzzese, Giovanni, Quartarone, Angelo, Tononi, Giulio, Di Rocco, Alessandro, Ghilardi, Maria Felice
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.03.2015
• Subjects: Adaptation; Aged; Consolidation; Female; Humans; Male; Middle Aged; Motor learning; Motor skills; Motor Skills - physiology; Neurology; Parietal Lobe - physiology; Parkinson Disease - psychology; Parkinson Disease - therapy; Retention (Psychology) - physiology; Transcranial Magnetic Stimulation; Consolidation; 5Hz-rTMS; PD; Motor learning; Motor skills; Adaptation; Parkinson's disease; 5 Hz-repetitive transcranial magnetic stimulation

In Parkinson's disease (PD), skill retention is poor, even when acquisition rate is generally preserved. Recent work in normal subjects suggests that 5 Hz-repetitive transcranial magnetic stimulation (5Hz-rTMS) may induce phenomena of long-term potentiation at the cortical level. We thus verifi...