No Elevated Plasma Catecholamine Levels during Sleep in Newly Diagnosed, Untreated Hypertensives

• Published in: PloS one Vol. 6; no. 6; p. e21292
• Main Authors: Rasch, Björn, Dodt, Christoph, Sayk, Friedhelm, Mölle, Matthias, Born, Jan
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 17.06.2011; Public Library of Science (PLoS)
• Subjects: Abnormalities; Adult; Arousal; Biology; Blood; Blood Pressure; Body mass index; Case-Control Studies; Catecholamine; Catecholamines; Chromatography; Epinephrine - blood; Heart Rate; Human subjects; Humans; Hypertension; Hypertension - blood; Hypertension - diagnosis; Hypertension - physiopathology; Hypertension - therapy; Hypotheses; Internal medicine; Laboratories; Male; Medical research; Medicine; Men; Metabolism; Morning; Nervous system; Neurosciences; Norepinephrine - blood; Plasma; Sleep; Sleep - physiology; Sleep and wakefulness; Sleep apnea; Sleep Stages - physiology; Studies; Supine position; Time Factors; Vital signs; Wakefulness; Wakefulness - physiology; United States > US; Germany; California

The sympatho-adrenergic system is highly involved in regulating sleep, wake and arousal states, and abnormalities in this system are regarded as a key factor in the development and progression of arterial hypertension. While hypertension is associated with a hyperadrenergic state during wakefulness,...