White Matter Integrity, Creativity, and Psychopathology: Disentangling Constructs with Diffusion Tensor Imaging

• Published in: PloS one Vol. 5; no. 3; p. e9818
• Main Authors: Jung, Rex E., Grazioplene, Rachael, Caprihan, Arvind, Chavez, Robert S., Haier, Richard J.
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 22.03.2010; Public Library of Science (PLoS)
• Subjects: Adolescent; Adult; Alzheimer's disease; Alzheimers disease; Anisotropy; Aspartate; Aspartic Acid - analogs & derivatives; Aspartic Acid - metabolism; Autism; Behavior; Behavior disorders; Bipolar disorder; Brain; Brain - pathology; Brain Mapping - methods; Brain research; Cognition; Cortex; Creativity; Dietary fiber; Diffusion; Diffusion rate; Diffusion Tensor Imaging - methods; Female; Frontal lobe; Frontal Lobe - pathology; Humans; Integrity; Laboratories; Magnetic resonance imaging; Male; Males; Mental disorders; Mental health; Mental Health/Neuropsychiatric Disorders; Mental Health/Schizophrenia and Other Psychoses; Metabolites; Neostriatum; Nervous system; Neuroimaging; Neuroscience/Behavioral Neuroscience; Neuroscience/Psychology; Neurosciences; Neuroses; NMR; Nuclear magnetic resonance; Observer Variation; Obsessive compulsive disorder; Personality; Psychological aspects; Psychology; Psychopathology; Psychosis; Schizophrenia; Substantia alba; Synesthesia; New Mexico; United States > US

That creativity and psychopathology are somehow linked remains a popular but controversial idea in neuroscience research. Brain regions implicated in both psychosis-proneness and creative cognition include frontal projection zones and association fibers. In normal subjects, we have previously demons...