The Genome of a Bacillus Isolate Causing Anthrax in Chimpanzees Combines Chromosomal Properties of B. cereus with B. anthracis Virulence Plasmids

• Published in: PloS one Vol. 5; no. 7; p. e10986
• Main Authors: Klee, Silke R., Brzuszkiewicz, Elzbieta B., Nattermann, Herbert, Brüggemann, Holger, Dupke, Susann, Wollherr, Antje, Franz, Tatjana, Pauli, Georg, Appel, Bernd, Liebl, Wolfgang, Couacy-Hymann, Emmanuel, Boesch, Christophe, Meyer, Frauke-Dorothee, Leendertz, Fabian H., Ellerbrok, Heinz, Gottschalk, Gerhard, Grunow, Roland, Liesegang, Heiko
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 09.07.2010; Public Library of Science (PLoS)
• Subjects: Acids; Analysis; Animals; Anthrax; Anthrax - microbiology; Anthrax - veterinary; Bacillus; Bacillus anthracis; Bacillus anthracis - genetics; Bacillus anthracis - pathogenicity; Bacillus cereus; Bacillus cereus - genetics; Bacillus thuringiensis; Bacteria; Bacterial genetics; Bacterial infections; Chimpanzees; Chromosomes; Chromosomes, Bacterial - genetics; Computational Biology; Diagnostic systems; Edema; Fatalities; Genes; Genetic aspects; Genetic research; Genetics; Genetics and Genomics/Genomics; Genome, Bacterial - genetics; Genomes; Genomics; Infectious Diseases/Bacterial Infections; Laboratories; Lungs; Metabolism; Microbiology; Microbiology/Microbial Evolution and Genomics; Models, Genetic; Mutation; Nonsense mutation; Nucleotide sequence; Pan troglodytes - microbiology; Plasmids; Plasmids - genetics; Primate Diseases - microbiology; Prophages; Rainforests; Regulon - genetics; Relational data bases; Virulence; Virulence - genetics; Germany

Anthrax is a fatal disease caused by strains of Bacillus anthracis. Members of this monophyletic species are non motile and are all characterized by the presence of four prophages and a nonsense mutation in the plcR regulator gene. Here we report the complete genome sequence of a Bacillus strain iso...