The impact of focused Gene Ontology curation of specific mammalian systems

The Gene Ontology (GO) resource provides dynamic controlled vocabularies to provide an information-rich resource to aid in the consistent description of the functional attributes and subcellular locations of gene products from all taxonomic groups (www.geneontology.org). System-focused projects, suc...

Full description

Saved in:

Bibliographic Details
Published in	PloS one Vol. 6; no. 12; p. e27541
Main Authors	Alam-Faruque, Yasmin, Huntley, Rachael P, Khodiyar, Varsha K, Camon, Evelyn B, Dimmer, Emily C, Sawford, Tony, Martin, Maria J, O'Donovan, Claire, Talmud, Philippa J, Scambler, Peter, Apweiler, Rolf, Lovering, Ruth C
Format	Journal Article
Language	English
Published	United States Public Library of Science 09.12.2011 Public Library of Science (PLoS)
Subjects	Animals Annotations Antigens Arthritis Automation Avian flu Bioinformatics Biology Consortia Controlled vocabularies Crohn's disease Crohns disease Cytokines Databases, Genetic Datasets DNA microarrays Extracellular matrix Gene expression Genes High-Throughput Nucleotide Sequencing Humans Hypertension Kidney - growth & development Kidney - metabolism Kidneys Macrophages - metabolism Macrophages - pathology Mammals - genetics Molecular Sequence Annotation - methods Oligonucleotide Array Sequence Analysis Ontology Proteins Proteomes Statistics as Topic Surfactants
Online Access	Get full text

Cover

Loading…

Abstract	The Gene Ontology (GO) resource provides dynamic controlled vocabularies to provide an information-rich resource to aid in the consistent description of the functional attributes and subcellular locations of gene products from all taxonomic groups (www.geneontology.org). System-focused projects, such as the Renal and Cardiovascular GO Annotation Initiatives, aim to provide detailed GO data for proteins implicated in specific organ development and function. Such projects support the rapid evaluation of new experimental data and aid in the generation of novel biological insights to help alleviate human disease. This paper describes the improvement of GO data for renal and cardiovascular research communities and demonstrates that the cardiovascular-focused GO annotations, created over the past three years, have led to an evident improvement of microarray interpretation. The reanalysis of cardiovascular microarray datasets confirms the need to continue to improve the annotation of the human proteome. GO ANNOTATION DATA IS FREELY AVAILABLE FROM: ftp://ftp.geneontology.org/pub/go/gene-associations/
AbstractList	The Gene Ontology (GO) resource provides dynamic controlled vocabularies to provide an information-rich resource to aid in the consistent description of the functional attributes and subcellular locations of gene products from all taxonomic groups (www.geneontology.org). System-focused projects, such as the Renal and Cardiovascular GO Annotation Initiatives, aim to provide detailed GO data for proteins implicated in specific organ development and function. Such projects support the rapid evaluation of new experimental data and aid in the generation of novel biological insights to help alleviate human disease. This paper describes the improvement of GO data for renal and cardiovascular research communities and demonstrates that the cardiovascular-focused GO annotations, created over the past three years, have led to an evident improvement of microarray interpretation. The reanalysis of cardiovascular microarray datasets confirms the need to continue to improve the annotation of the human proteome. GO ANNOTATION DATA IS FREELY AVAILABLE FROM: ftp://ftp.geneontology.org/pub/go/gene-associations/ The Gene Ontology (GO) resource provides dynamic controlled vocabularies to provide an information-rich resource to aid in the consistent description of the functional attributes and subcellular locations of gene products from all taxonomic groups (www.geneontology.org). System-focused projects, such as the Renal and Cardiovascular GO Annotation Initiatives, aim to provide detailed GO data for proteins implicated in specific organ development and function. Such projects support the rapid evaluation of new experimental data and aid in the generation of novel biological insights to help alleviate human disease. This paper describes the improvement of GO data for renal and cardiovascular research communities and demonstrates that the cardiovascular-focused GO annotations, created over the past three years, have led to an evident improvement of microarray interpretation. The reanalysis of cardiovascular microarray datasets confirms the need to continue to improve the annotation of the human proteome. The Gene Ontology (GO) resource provides dynamic controlled vocabularies to provide an information-rich resource to aid in the consistent description of the functional attributes and subcellular locations of gene products from all taxonomic groups (www.geneontology.org). System-focused projects, such as the Renal and Cardiovascular GO Annotation Initiatives, aim to provide detailed GO data for proteins implicated in specific organ development and function. Such projects support the rapid evaluation of new experimental data and aid in the generation of novel biological insights to help alleviate human disease. This paper describes the improvement of GO data for renal and cardiovascular research communities and demonstrates that the cardiovascular-focused GO annotations, created over the past three years, have led to an evident improvement of microarray interpretation. The reanalysis of cardiovascular microarray datasets confirms the need to continue to improve the annotation of the human proteome. Availability GO annotation data is freely available from: ftp://ftp.geneontology.org/pub/go/gene-associations/ The Gene Ontology (GO) resource provides dynamic controlled vocabularies to provide an information-rich resource to aid in the consistent description of the functional attributes and subcellular locations of gene products from all taxonomic groups ( www.geneontology.org ). System-focused projects, such as the Renal and Cardiovascular GO Annotation Initiatives, aim to provide detailed GO data for proteins implicated in specific organ development and function. Such projects support the rapid evaluation of new experimental data and aid in the generation of novel biological insights to help alleviate human disease. This paper describes the improvement of GO data for renal and cardiovascular research communities and demonstrates that the cardiovascular-focused GO annotations, created over the past three years, have led to an evident improvement of microarray interpretation. The reanalysis of cardiovascular microarray datasets confirms the need to continue to improve the annotation of the human proteome. UNLABELLEDThe Gene Ontology (GO) resource provides dynamic controlled vocabularies to provide an information-rich resource to aid in the consistent description of the functional attributes and subcellular locations of gene products from all taxonomic groups (www.geneontology.org). System-focused projects, such as the Renal and Cardiovascular GO Annotation Initiatives, aim to provide detailed GO data for proteins implicated in specific organ development and function. Such projects support the rapid evaluation of new experimental data and aid in the generation of novel biological insights to help alleviate human disease. This paper describes the improvement of GO data for renal and cardiovascular research communities and demonstrates that the cardiovascular-focused GO annotations, created over the past three years, have led to an evident improvement of microarray interpretation. The reanalysis of cardiovascular microarray datasets confirms the need to continue to improve the annotation of the human proteome.AVAILABILITYGO ANNOTATION DATA IS FREELY AVAILABLE FROM: ftp://ftp.geneontology.org/pub/go/gene-associations/ The Gene Ontology (GO) resource provides dynamic controlled vocabularies to provide an information-rich resource to aid in the consistent description of the functional attributes and subcellular locations of gene products from all taxonomic groups (www.geneontology.org). System-focused projects, such as the Renal and Cardiovascular GO Annotation Initiatives, aim to provide detailed GO data for proteins implicated in specific organ development and function. Such projects support the rapid evaluation of new experimental data and aid in the generation of novel biological insights to help alleviate human disease. This paper describes the improvement of GO data for renal and cardiovascular research communities and demonstrates that the cardiovascular-focused GO annotations, created over the past three years, have led to an evident improvement of microarray interpretation. The reanalysis of cardiovascular microarray datasets confirms the need to continue to improve the annotation of the human proteome. Availability GO annotation data is freely available from: ftp://ftp.geneontology.org/pub/go/gene-associations/ The Gene Ontology (GO) resource provides dynamic controlled vocabularies to provide an information-rich resource to aid in the consistent description of the functional attributes and subcellular locations of gene products from all taxonomic groups (www.geneontology.org). System-focused projects, such as the Renal and Cardiovascular GO Annotation Initiatives, aim to provide detailed GO data for proteins implicated in specific organ development and function. Such projects support the rapid evaluation of new experimental data and aid in the generation of novel biological insights to help alleviate human disease. This paper describes the improvement of GO data for renal and cardiovascular research communities and demonstrates that the cardiovascular-focused GO annotations, created over the past three years, have led to an evident improvement of microarray interpretation. The reanalysis of cardiovascular microarray datasets confirms the need to continue to improve the annotation of the human proteome.GO ANNOTATION DATA IS FREELY AVAILABLE FROM: ftp://ftp.geneontology.org/pub/go/gene-associations/
Audience	Academic
Author	Sawford, Tony Martin, Maria J Apweiler, Rolf Dimmer, Emily C Scambler, Peter O'Donovan, Claire Khodiyar, Varsha K Alam-Faruque, Yasmin Huntley, Rachael P Camon, Evelyn B Talmud, Philippa J Lovering, Ruth C
AuthorAffiliation	1 EMBL-European Bioinformatics Institute, Hinxton, Cambridge, United Kingdom University College Dublin, Ireland 2 Centre for Cardiovascular Genetics, Institute of Cardiovascular Science, University College London, London, United Kingdom 3 Molecular Medicine Unit, Institute of Child Health, University College London, London, United Kingdom
AuthorAffiliation_xml	– name: 2 Centre for Cardiovascular Genetics, Institute of Cardiovascular Science, University College London, London, United Kingdom – name: University College Dublin, Ireland – name: 1 EMBL-European Bioinformatics Institute, Hinxton, Cambridge, United Kingdom – name: 3 Molecular Medicine Unit, Institute of Child Health, University College London, London, United Kingdom
Author_xml	– sequence: 1 givenname: Yasmin surname: Alam-Faruque fullname: Alam-Faruque, Yasmin organization: EMBL-European Bioinformatics Institute, Hinxton, Cambridge, United Kingdom – sequence: 2 givenname: Rachael P surname: Huntley fullname: Huntley, Rachael P – sequence: 3 givenname: Varsha K surname: Khodiyar fullname: Khodiyar, Varsha K – sequence: 4 givenname: Evelyn B surname: Camon fullname: Camon, Evelyn B – sequence: 5 givenname: Emily C surname: Dimmer fullname: Dimmer, Emily C – sequence: 6 givenname: Tony surname: Sawford fullname: Sawford, Tony – sequence: 7 givenname: Maria J surname: Martin fullname: Martin, Maria J – sequence: 8 givenname: Claire surname: O'Donovan fullname: O'Donovan, Claire – sequence: 9 givenname: Philippa J surname: Talmud fullname: Talmud, Philippa J – sequence: 10 givenname: Peter surname: Scambler fullname: Scambler, Peter – sequence: 11 givenname: Rolf surname: Apweiler fullname: Apweiler, Rolf – sequence: 12 givenname: Ruth C surname: Lovering fullname: Lovering, Ruth C
BackLink	https://www.ncbi.nlm.nih.gov/pubmed/22174742$$D View this record in MEDLINE/PubMed
BookMark	eNqNkl-L1DAUxYusuH_0G4gWBMWHGXObNG1fhGXRdWRhQFdfw216M5OhbWabVpxvb8bpLlPZB8lDws3vnCQ35zw6aV1LUfQS2Bx4Bh82buharOfbUJ4zlmSpgCfRGRQ8mcmE8ZOj9Wl07v2GsZTnUj6LTpMEMpGJ5Cz6erum2DZb1H3sTGycHjxV8TW1FC_b3tVutYv10GFvXbsn_Ja0NVbHDTYN1hbb2O98T41_Hj01WHt6Mc4X0Y_Pn26vvsxulteLq8ubmZYF9LMScmMKkSVclBwYaCJJoE3KBWrBUw4gUhSQFsigxBKAjM4MIskSc8r5RfT64LutnVdjG7wCDgnIIknTQCwOROVwo7adbbDbKYdW_S24bqWw662uSeVScMikoZJVQktTAGYVFUbkpBPCLHh9HE8byoYqTW3fYT0xne60dq1W7pfiCU9ZIYPBu9Ggc3cD-V411muqa2zJDV4VAIUoGIhAvvmHfPxxI7XCcH_bGheO1XtPdSkymUuWAQvU_BEqjIoaq0NkjA31ieD9RBCYnn73Kxy8V4vv3_6fXf6csm-P2DVh3a-9q4d9nvwUFAdQd877jsxDj4GpfeLvu6H2iVdj4oPs1fH_PIjuI87_AIim_Ok
CitedBy_id	crossref_primary_10_1016_j_tig_2014_10_001 crossref_primary_10_1261_rna_065565_118 crossref_primary_10_1186_2041_1480_4_S1_S4 crossref_primary_10_3390_genes9120593 crossref_primary_10_1093_database_bav009 crossref_primary_10_1093_nar_gku1113 crossref_primary_10_1098_rsob_200149 crossref_primary_10_3892_mmr_2013_1498 crossref_primary_10_1007_s12021_015_9293_2 crossref_primary_10_1186_1471_2105_15_45 crossref_primary_10_1093_database_bat054 crossref_primary_10_1021_acs_jproteome_7b00235 crossref_primary_10_1186_2047_217X_3_4 crossref_primary_10_1186_s12859_015_0622_0 crossref_primary_10_1371_journal_pone_0170712 crossref_primary_10_1097_MD_0000000000031065 crossref_primary_10_1371_journal_pone_0099864 crossref_primary_10_1093_cvr_cvs346 crossref_primary_10_1261_rna_055301_115
ContentType	Journal Article
Copyright	COPYRIGHT 2011 Public Library of Science 2011 Alam-Faruque et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License: https://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. Alam-Faruque et al. 2011
Copyright_xml	– notice: COPYRIGHT 2011 Public Library of Science – notice: 2011 Alam-Faruque et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License: https://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. – notice: Alam-Faruque et al. 2011
DBID	CGR CUY CVF ECM EIF NPM AAYXX CITATION IOV ISR 3V. 7QG 7QL 7QO 7RV 7SN 7SS 7T5 7TG 7TM 7U9 7X2 7X7 7XB 88E 8AO 8C1 8FD 8FE 8FG 8FH 8FI 8FJ 8FK ABJCF ABUWG AFKRA ARAPS ATCPS AZQEC BBNVY BENPR BGLVJ BHPHI C1K CCPQU D1I DWQXO FR3 FYUFA GHDGH GNUQQ H94 HCIFZ K9. KB. KB0 KL. L6V LK8 M0K M0S M1P M7N M7P M7S NAPCQ P5Z P62 P64 PATMY PDBOC PIMPY PQEST PQQKQ PQUKI PRINS PTHSS PYCSY RC3 7X8 5PM DOA
DOI	10.1371/journal.pone.0027541
DatabaseName	Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed CrossRef Opposing Viewpoints Resource Center Gale In Context: Science ProQuest Central (Corporate) Animal Behavior Abstracts Bacteriology Abstracts (Microbiology B) Biotechnology Research Abstracts Nursing & Allied Health Database (ProQuest) Ecology Abstracts Entomology Abstracts (Full archive) Immunology Abstracts Meteorological & Geoastrophysical Abstracts Nucleic Acids Abstracts Virology and AIDS Abstracts Agricultural Science Collection Health & Medical Collection ProQuest Central (purchase pre-March 2016) Medical Database (Alumni Edition) ProQuest Pharma Collection Public Health Database Technology Research Database ProQuest SciTech Collection ProQuest Technology Collection ProQuest Natural Science Collection Hospital Premium Collection Hospital Premium Collection (Alumni Edition) ProQuest Central (Alumni) (purchase pre-March 2016) Materials Science & Engineering Collection ProQuest Central (Alumni) ProQuest Central Advanced Technologies & Aerospace Collection Agricultural & Environmental Science Collection ProQuest Central Essentials Biological Science Collection AUTh Library subscriptions: ProQuest Central Technology Collection Natural Science Collection Environmental Sciences and Pollution Management ProQuest One Community College ProQuest Materials Science Collection ProQuest Central Korea Engineering Research Database Health Research Premium Collection Health Research Premium Collection (Alumni) ProQuest Central Student AIDS and Cancer Research Abstracts SciTech Premium Collection ProQuest Health & Medical Complete (Alumni) Materials Science Database Nursing & Allied Health Database (Alumni Edition) Meteorological & Geoastrophysical Abstracts - Academic ProQuest Engineering Collection Biological Sciences Agriculture Science Database Health & Medical Collection (Alumni Edition) Medical Database Algology Mycology and Protozoology Abstracts (Microbiology C) Biological Science Database Engineering Database Nursing & Allied Health Premium Advanced Technologies & Aerospace Database ProQuest Advanced Technologies & Aerospace Collection Biotechnology and BioEngineering Abstracts Environmental Science Database Materials Science Collection Publicly Available Content (ProQuest) ProQuest One Academic Eastern Edition (DO NOT USE) ProQuest One Academic ProQuest One Academic UKI Edition ProQuest Central China Engineering Collection Environmental Science Collection Genetics Abstracts MEDLINE - Academic PubMed Central (Full Participant titles) Directory of Open Access Journals
DatabaseTitle	MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) CrossRef Agricultural Science Database Publicly Available Content Database ProQuest Central Student ProQuest Advanced Technologies & Aerospace Collection ProQuest Central Essentials Nucleic Acids Abstracts SciTech Premium Collection ProQuest Central China Environmental Sciences and Pollution Management Health Research Premium Collection Meteorological & Geoastrophysical Abstracts Natural Science Collection Biological Science Collection ProQuest Medical Library (Alumni) Engineering Collection Advanced Technologies & Aerospace Collection Engineering Database Virology and AIDS Abstracts ProQuest Biological Science Collection ProQuest One Academic Eastern Edition Agricultural Science Collection ProQuest Hospital Collection ProQuest Technology Collection Health Research Premium Collection (Alumni) Biological Science Database Ecology Abstracts ProQuest Hospital Collection (Alumni) Biotechnology and BioEngineering Abstracts Environmental Science Collection Entomology Abstracts Nursing & Allied Health Premium ProQuest Health & Medical Complete ProQuest One Academic UKI Edition Environmental Science Database ProQuest Nursing & Allied Health Source (Alumni) Engineering Research Database ProQuest One Academic Meteorological & Geoastrophysical Abstracts - Academic Technology Collection Technology Research Database Materials Science Collection ProQuest Health & Medical Complete (Alumni) ProQuest Central (Alumni Edition) ProQuest One Community College ProQuest Natural Science Collection ProQuest Pharma Collection ProQuest Central Genetics Abstracts ProQuest Engineering Collection Biotechnology Research Abstracts Health and Medicine Complete (Alumni Edition) ProQuest Central Korea Bacteriology Abstracts (Microbiology B) Algology Mycology and Protozoology Abstracts (Microbiology C) Agricultural & Environmental Science Collection AIDS and Cancer Research Abstracts Materials Science Database ProQuest Materials Science Collection ProQuest Public Health ProQuest Nursing & Allied Health Source ProQuest SciTech Collection Advanced Technologies & Aerospace Database ProQuest Medical Library Animal Behavior Abstracts Materials Science & Engineering Collection Immunology Abstracts ProQuest Central (Alumni) MEDLINE - Academic
DatabaseTitleList	MEDLINE Agricultural Science Database MEDLINE - Academic
Database_xml	– sequence: 1 dbid: DOA name: DOAJ Directory of Open Access Journals url: https://www.doaj.org/ sourceTypes: Open Website – sequence: 2 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 3 dbid: EIF name: MEDLINE url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search sourceTypes: Index Database – sequence: 4 dbid: 8FG name: ProQuest Technology Collection url: https://search.proquest.com/technologycollection1 sourceTypes: Aggregation Database
DeliveryMethod	fulltext_linktorsrc
Discipline	Sciences (General) Biology
DocumentTitleAlternate	Mammalian Gene Ontology Curation
EISSN	1932-6203
Editor	Haslam, Niall James
Editor_xml	– sequence: 1 givenname: Niall James surname: Haslam fullname: Haslam, Niall James
EndPage	e27541
ExternalDocumentID	1312169255 oai_doaj_org_article_8643176feb0d4c6f91a7de9f48ec2ea7 2900519321 A476860710 10_1371_journal_pone_0027541 22174742
Genre	Research Support, Non-U.S. Gov't Journal Article Research Support, N.I.H., Extramural
GrantInformation_xml	– fundername: NHGRI NIH HHS grantid: R01 HG002273 – fundername: British Heart Foundation grantid: SP/07/007/23671 – fundername: NHGRI NIH HHS grantid: R01HG02273-02 – fundername: British Heart Foundation grantid: RG/10/13/28570
GroupedDBID	--- 123 29O 2WC 3V. 53G 5VS 7RV 7X2 7X7 7XC 88E 8AO 8C1 8CJ 8FE 8FG 8FH 8FI 8FJ A8Z AAFWJ ABDBF ABIVO ABJCF ABUWG ACGFO ACIHN ACIWK ACPRK ADBBV ADRAZ AEAQA AENEX AFKRA AFRAH AHMBA ALIPV ALMA_UNASSIGNED_HOLDINGS AOIJS APEBS ARAPS ATCPS BAWUL BBNVY BBORY BCNDV BENPR BGLVJ BHPHI BKEYQ BPHCQ BVXVI BWKFM CCPQU CGR CS3 CUY CVF D1I D1J D1K DIK DU5 E3Z EAP EAS EBD ECM EIF EMOBN ESTFP ESX EX3 F5P FPL FYUFA GROUPED_DOAJ GX1 HCIFZ HH5 HMCUK HYE IAO IEA IHR IHW INH INR IOV IPNFZ IPY ISE ISR ITC K6- KB. KQ8 L6V LK5 LK8 M0K M1P M48 M7P M7R M7S M~E NAPCQ NPM O5R O5S OK1 P2P P62 PATMY PDBOC PIMPY PQQKQ PROAC PSQYO PTHSS PV9 PYCSY RIG RNS RPM RZL SV3 TR2 UKHRP WOQ WOW ~02 ~KM AAYXX CITATION AFPKN 7QG 7QL 7QO 7SN 7SS 7T5 7TG 7TM 7U9 7XB 8FD 8FK AZQEC C1K DWQXO FR3 GNUQQ H94 K9. KL. M7N P64 PQEST PQUKI PRINS RC3 7X8 5PM ACUHS AAPBV ABPTK N95
ID	FETCH-LOGICAL-c691t-b18ff947234b3101cee6e1cf534ac43531145a4159a01bab11efc7faae6ba8e83
IEDL.DBID	RPM
ISSN	1932-6203
IngestDate	Sun Jun 04 06:37:08 EDT 2023 Tue Dec 17 15:25:49 EST 2024 Tue Sep 17 21:25:54 EDT 2024 Fri Oct 25 04:25:38 EDT 2024 Thu Dec 12 14:27:40 EST 2024 Tue Nov 19 20:38:09 EST 2024 Tue Nov 12 22:36:48 EST 2024 Thu Aug 01 20:24:04 EDT 2024 Thu Aug 01 19:18:38 EDT 2024 Tue Aug 20 22:08:44 EDT 2024 Thu Nov 21 23:28:28 EST 2024 Wed Oct 16 00:44:22 EDT 2024
IsDoiOpenAccess	true
IsOpenAccess	true
IsPeerReviewed	true
IsScholarly	true
Issue	12
Language	English
License	This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited. Creative Commons Attribution License
LinkModel	DirectLink
MergedId	FETCHMERGED-LOGICAL-c691t-b18ff947234b3101cee6e1cf534ac43531145a4159a01bab11efc7faae6ba8e83
Notes	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 Conceived and designed the experiments: RCL RA ECD PS PJT. Performed the experiments: YA-F VKK RCL EBC RPH ECD. Analyzed the data: RPH RCL. Contributed reagents/materials/analysis tools: TJS MJM. Wrote the paper: YA-F RPH ECD COD RCL.
OpenAccessLink	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3235096/
PMID	22174742
PQID	1312169255
PQPubID	1436336
PageCount	e27541
ParticipantIDs	plos_journals_1312169255 doaj_primary_oai_doaj_org_article_8643176feb0d4c6f91a7de9f48ec2ea7 pubmedcentral_primary_oai_pubmedcentral_nih_gov_3235096 proquest_miscellaneous_911949014 proquest_journals_1312169255 gale_infotracmisc_A476860710 gale_infotracacademiconefile_A476860710 gale_incontextgauss_ISR_A476860710 gale_incontextgauss_IOV_A476860710 gale_healthsolutions_A476860710 crossref_primary_10_1371_journal_pone_0027541 pubmed_primary_22174742
PublicationCentury	2000
PublicationDate	2011-12-09
PublicationDateYYYYMMDD	2011-12-09
PublicationDate_xml	– month: 12 year: 2011 text: 2011-12-09 day: 09
PublicationDecade	2010
PublicationPlace	United States
PublicationPlace_xml	– name: United States – name: San Francisco – name: San Francisco, USA
PublicationTitle	PloS one
PublicationTitleAlternate	PLoS One
PublicationYear	2011
Publisher	Public Library of Science Public Library of Science (PLoS)
Publisher_xml	– sequence: 0 name: Public Library of Science – sequence: 0 name: Public Library of Science (PLoS) – name: Public Library of Science
SSID	ssj0053866
Score	2.1968653
Snippet	The Gene Ontology (GO) resource provides dynamic controlled vocabularies to provide an information-rich resource to aid in the consistent description of the... UNLABELLEDThe Gene Ontology (GO) resource provides dynamic controlled vocabularies to provide an information-rich resource to aid in the consistent description...
SourceID	plos doaj pubmedcentral proquest gale crossref pubmed
SourceType	Open Website Open Access Repository Aggregation Database Index Database
StartPage	e27541
SubjectTerms	Animals Annotations Antigens Arthritis Automation Avian flu Bioinformatics Biology Consortia Controlled vocabularies Crohn's disease Crohns disease Cytokines Databases, Genetic Datasets DNA microarrays Extracellular matrix Gene expression Genes High-Throughput Nucleotide Sequencing Humans Hypertension Kidney - growth & development Kidney - metabolism Kidneys Macrophages - metabolism Macrophages - pathology Mammals - genetics Molecular Sequence Annotation - methods Oligonucleotide Array Sequence Analysis Ontology Proteins Proteomes Statistics as Topic Surfactants
SummonAdditionalLinks	– databaseName: Directory of Open Access Journals dbid: DOA link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwrV1Lb9QwELbQnrggyquBAhZCAg6h8SNOfCyIqlSCSkBRb5bt2AWJTVZkc-DfMxNnowZVggPX9STKfjP2zNgznwl5zqvohQ51LpWQuWx4CetgLfPS8tKz6JVosHf4w0d1ci5PL8qLK1d9YU1YogdOwB3WCl2cisEVjfQqamarJugo6-B5sKmPvOC7ZCqtwTCLlZoa5UTFDie9vN50bcAtlKqUbOGIRr7-eVVebX50_XUh55-Vk1dc0fFtcmuKIelR-vY9ciO0d8jeNEt7-nKikn51l5yCFdDUCEm7SGPnhz40FAXoWTteXfuL-iFZAUpg4yUWD9G1Xa_HLRCauJ77e-T8-N2Xtyf5dHtC7pVm29yxOkYtKy6kgxiOgTdUgflYCmk9BEkCMqHSgv_WtmDOOsZC9FW0Nihn61CL-2TVAl77hNZlcLpwMR3KNcKVwWKg47AxNzZ1RvIdlGaTSDLMeFJWQXKRMDEIvZmgz8gbxHuWRYrr8QdQvJkUb_6m-Iw8RW2Z1C86T1RzJCGDQta8IiPPRgmkuWixjubSDn1v3p99_Qehz58WQi8modiB3r2dehfgPyF91kLyYCEJk9UvhvfRtnao9IAR40xpSOzgyZ29XT9M52F8KdbGtaEbegPuSks8Dc_Ig2SdM7AcE85K8oxUC7tdIL8cab9_G0nGBRfIDPTwf6jqEbk5bsVjFZA-IKvtzyE8hlhu656M0_Y3J55HsA priority: 102 providerName: Directory of Open Access Journals – databaseName: ProQuest Technology Collection dbid: 8FG link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwjV1Lb9QwELZguXBBlFcDBSyEBBxC17FjOydUKpa2UqkEFPVm2Y7dVqLJttkc-u_xOM5CUIW4ridRdjwvj2e-Qeh1IbyllZM545TlrC7KYAcly0tdlJZ4y2kNvcOHX_jeMTs4KU9Swq1LZZWjTYyGum4t5Mi3CSUF4VWIgD8sL3OYGgW3q2mExm10hxSCQ0mfXHweLXHQZc5TuxwVZDvtzvtl2zhIpIiSkYk7iqj9a9s8W_5su5sCz7_rJ_9wSIv76F6KJPHOsPUb6JZrHqCNpKsdfpsApd89RAdBFvB-bIfErceL1vadqzEQ4KMmDrC9xrv9IAtAEYfS-3OLD_XFRUyE4IRs_ggdLz59393L0wyF3PKKrHJDpPcVEwVlJkRyJPhE7oj1JWXahlCJhvNQqYMXr_ScGG0Icd4Kr7XjRksn6WM0awK_NhGWpTPV3Pjhaq6mpnQawh0D7bm-lhnKR1aq5QCVoeJ9mQhHjIEnClivEusz9BH4vaYFoOv4Q3t1qpLeKMkhwuHemXnNLPcV0aJ2lWfS2cJpkaGXsFtq6Bpdq6vaYeEcBdh58wy9ihQAdtFANc2p7rtO7R_9-A-ib18nRG8SkW_DvludOhjCfwIQrQnl1oQyqKydLG-CbI1c6dRv4Q5PjvJ28zJeL8NLoUKucW3fqeC0KgZ34hl6MkjnmrEFHDsFKzIkJnI74fx0pTk_i1DjtKCAD_T031_1DN2NqXao8qm20Gx11bvnIVZbmRdRIX8BJmo9aw priority: 102 providerName: ProQuest – databaseName: Scholars Portal Journals: Open Access dbid: M48 link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwjV3da9RAEF_K-eKLWL8arbqIoD6kZD-ySR5EavFoC2dBPelb2N3stoU2OS8XsP-9O5tNMHKir9lJIL_MZGZ2Z36D0GuaWc0Kk8dcMB7ziqbuP5jzOJU01cRqwSroHV58FsdLfnqenu-gYWZrALDdmtrBPKnl-vrg54_bD87g3_upDRkZbjpYNbWBDZIshU72O9T5RijyWvDxXMFZtz-9hKglFjRhoZnub0-ZOCvP6T_-uWer66bdFpb-WV35m7ua30f3QpyJD3vF2EU7pn6AdoMlt_htoJt-9xCdOk3BJ75ZEjcWzxvdtabCIIDPaj_e9hYfdb2mgIQfWW-vNF7Imxu_TYID7_kjtJx_-nZ0HIcJC7EWBdnEiuTWFjyjjCsX5xHnMYUh2qaMS-0CKeaypVQ6H1_IhCipCDFWZ1ZKI5TMTc4eo1nt8NpDOE-NKhJl-4O7iqnUSAiGFDTv2iqPUDxAWa56Io3Sn6ZlLgHpMSkB-jJAH6GPgPcoCzTY_kKzviiDVZW5gPhHWKOSimthCyKzyhSW50ZTI7MIvYSvVfY9paMxl4fcZVnArJdE6JWXACqMGmptLmTXtuXJ2ff_EPr6ZSL0JgjZxn13LUN_g3snoNiaSO5PJJ1B68nyHujWgErrMCKUiMIlf-7OQd-2L-NxGR4K9XO1abq2dC6t4HBiHqEnvXaOwFJISjNOI5RN9HaC_HSlvrr0ROSMMmAPevpPlJ-hu34vHsqAin0026w789wFcxv1wtvnL-LeRkA priority: 102 providerName: Scholars Portal
Title	The impact of focused Gene Ontology curation of specific mammalian systems
URI	https://www.ncbi.nlm.nih.gov/pubmed/22174742 https://www.proquest.com/docview/1312169255 https://search.proquest.com/docview/911949014 https://pubmed.ncbi.nlm.nih.gov/PMC3235096 https://doaj.org/article/8643176feb0d4c6f91a7de9f48ec2ea7 http://dx.doi.org/10.1371/journal.pone.0027541
Volume	6
hasFullText	1
inHoldings	1
isFullTextHit
isPrint
link	http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV3db9MwELe2IiReEBsfK4xiISTgIW2dOE7yuFUr26Ru02Cob5Ht2KPSmlRL-7D_njvHqQjaA-LFD_UlSu_Dd2ff_UzIpzCxOspMGnAR8YAXYQzrYMqDWIaxZlaLqMDe4dmFOL3h5_N4vkPithfGFe1rtRiWd8thufjlaitXSz1q68RGV7NJFEaIWjLaJbvgftsUvVl-wYCF8D1yUcJGXiTDVVUa3D1JYo63w4QYiic87Lgjh9q_XZt7q7uqfizw_Lt-8g-HNH1BnvtIkh41X7xHdky5T542d0s-7JM9b7U1_eKhpb--JOegFfTMNUbSytJppTe1KSgS0MvSXWX7QCebRiuQwl1PbxeazuRy6bZEqMc4f0Vupic_JqeBv00h0CJj60Cx1NqMJ2HEFcR0DLyjMEzbOOJSQ9AUQWYUS_DnmRwzJRVjxurESmmEkqlJo9ekVwITDwhNY6OysbLNIV0RqdhIDHwUNuraIu2ToGVqvmpAM3J3cpZAstFwJ0d55F4efXKMnN_SIuS1-6G6v8294PNUYKwjrFHjgmthMyaTwmSWp0aHRiZ98gHlljf9o1vDzY84ZFSIojfuk4-OAmEvSqyruZWbus7PLn_-A9H36w7RZ09kK9AALX0vA_wnhNPqUB52KMF4dWf6ALWs5UoNPGIhExkkevBkq3mPT9PtNL4Ua-VKU23qHNxXxvF0vE_eNHq6ZWyr9X2SdDS4w_nuDNigAx33Nvf2v598R565_XgsBcoOSW99vzHvIaBbqwGY8TyBMZ0wHKffBuTJ8cnF1fXAbZHAOOPpwJn5bxwpT1k
link.rule.ids	230,314,727,780,784,864,885,2102,2221,12056,12223,12765,21388,24318,27924,27925,31719,31720,33266,33267,33373,33374,33744,33745,43310,43579,43600,43805,53791,53793,73745,74014,74035,74302
linkProvider	National Library of Medicine
linkToHtml	http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwjV3db9MwELege4AXxPhaYDALIQEPYXXsOMkT2qZV7Vg7NDa0N8t27DGJJWVpHvjv8TluIGhCvNaXKD3fl893v0PoTZJZTQuTx4xTFrMySZ0dzFmcyiTVxGpOS-gdni_49JwdXaQXIeHWhLLKtU30hrqsNeTIdwklCeGFi4A_Ln_EMDUKblfDCI27aAOQ09MR2tg_XHw-Xdtip82ch4Y5mpHdsD8flnVlIJWSpYwMHJLH7e-t82j5vW5uCz3_rqD8wyVNHqIHIZbEe93mb6I7pnqENoO2NvhdgJR-_xgdOWnAM98QiWuLJ7VuG1NiIMAnlR9h-xMftJ00AIUfS2-vNJ7L62ufCsEB2_wJOp8cnh1M4zBFIda8IKtYkdzagmUJZcrFcsR5RW6ItillUrtgiboTUSqdHy_kmCipCDFWZ1ZKw5XMTU6folHl-LWFcJ4aVYyV7S7nSqpSIyHgUdCga8s8QvGalWLZgWUIf2OWuUNGxxMBrBeB9RHaB373tAB17X-oby5F0ByRc4hxuDVqXDLNbUFkVprCstzoxMgsQjuwW6LrG-0VVuwxd5IC9LxxhF57CoC7qKCe5lK2TSNmJ1__g-jL6YDobSCytdt3LUMPg_tPAKM1oNweUDql1YPlLZCtNVca8Vu83ZNrebt9GffL8FKokatM3TbCua2Cwa14hJ510tkzNoGDZ8aSCGUDuR1wfrhSXX3zYOM0oYAQ9PzfX7WD7k3P5sfieLb49ALd94l3qPkpttFoddOaly5yW6lXQT1_AX3RQbw
linkToPdf	http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwjV3db9MwELegkxAviPG1wGAWQgIeQuvYcZIntI1V62DdNBjam2U79pjEkm5pH_bf43OcQNCEeK0vUXq-L5_vfofQmySzmhYmjxmnLGZlkjo7mLM4lUmqidWcltA7fDjn-6fs4Cw9C_VPTSir7GyiN9RlrSFHPiaUJIQXLgIe21AWcfxp-nFxFcMEKbhpDeM07qI15xUnyQit7ezNj086u-w0m_PQPEczMg579WFRVwbSKlnKyMA5eQz_3lKPFj_r5rYw9O9qyj_c0_QhehDiSrzdCsI6umOqR2g9aG6D3wV46feP0YGTDDzzzZG4tnha61VjSgwE-Kjy42xv8O6qlQyg8CPq7YXGh_Ly0qdFcMA5f4JOp3vfdvfjMFEh1rwgy1iR3NqCZQllysV1xHlIboi2KWVSu8CJutNRKp1PL-SEKKkIMVZnVkrDlcxNTp-iUeX4tYFwnhpVTJRtL-pKqlIjIfhR0KxryzxCccdKsWiBM4S_PcvcgaPliQDWi8D6CO0Av3tagL32P9TX5yJokcg5xDvcGjUpmea2IDIrTWFZbnRiZBahLdgt0faQ9sortpk7VQGS3iRCrz0FQF9UIETnctU0Ynb0_T-Ivp4MiN4GIlu7fdcy9DO4_wSQWgPKzQGlU2A9WN4A2eq40ojfou6e7OTt9mXcL8NLoV6uMvWqEc6FFQxuyCP0rJXOnrEJHEIzlkQoG8jtgPPDlerihwcepwkFtKDn__6qLXTPaab4Mpt_foHu-xw8lP8Um2i0vF6Zly6IW6pXQTt_AaJ3Rek
openUrl	ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=The+Impact+of+Focused+Gene+Ontology+Curation+of+Specific+Mammalian+Systems&rft.jtitle=PloS+one&rft.au=Huntley%2C+Rachael+P&rft.au=Scambler%2C+Peter&rft.au=Camon%2C+Evelyn+B&rft.au=Khodiyar%2C+Varsha+K&rft.date=2011-12-09&rft.pub=Public+Library+of+Science&rft.issn=1932-6203&rft.eissn=1932-6203&rft.volume=6&rft.issue=12&rft.spage=e27541&rft_id=info:doi/10.1371%2Fjournal.pone.0027541&rft.externalDBID=n%2Fa&rft.externalDocID=A476860710
thumbnail_l	http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=1932-6203&client=summon
thumbnail_m	http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=1932-6203&client=summon
thumbnail_s	http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=1932-6203&client=summon