Insulin Resistance in Non-Obese Subjects Is Associated with Activation of the JNK Pathway and Impaired Insulin Signaling in Skeletal Muscle - Masharani, Umesh B.; Maddux, Betty A.; Li, Xiaojuan; Sakkas, Giorgos K.; Mulligan, Kathleen; Schambelan, Morris; Goldfine, Ira D.; Youngren, Jack F. (PloS one, 2011)
Keywords: Activation; Adult; Biology; Dual energy X-ray absorptiometry; Enzyme Activation; Female; Glucose; Humans; Insulin; Insulin - metabolism; Insulin receptor substrate 1; Insulin Resistance; JNK protein; Kinases; Lipids; Magnetic resonance imaging; Male; MAP kinase; MAP Kinase Kinase 4 - metabolism; Medicine; Muscle, Skeletal - metabolism; Obesity; Pathogenesis; Phosphorylation; Phosphotransferases; Physical fitness; Proteins; Serine; Signal Transduction; Signaling; Skeletal muscle; Stress; Stresses; Tissues; Type 2 diabetes; Tyrosine; United States--US; San Francisco California; California