Extracellular matrix derived from human urine-derived stem cells enhances the expansion, adhesion, spreading, and differentiation of human periodontal ligament stem cells

• Published in: Stem cell research & therapy Vol. 10; no. 1; pp. 396 - 16
• Main Authors: Xiong, Xue, Yang, Xiao, Dai, Hongwei, Feng, Gang, Zhang, Yuanyuan, Zhou, Jianping, Zhou, Wenwen
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 18.12.2019; BioMed Central; BMC
• Subjects: Angiogenesis; Biological products; Biomaterials; Cell culture; Cell expansion; Cholera; Epidermal growth factor; Extracellular matrix; Fibronectin; Fibronectins; Human periodontal ligament stem cells; Human urine-derived stem cells; Ligaments; Medical research; Mesenchyme; Osteogenesis; Penicillin; Periodontal ligament; Spreading; Stem cells; Tissue culture; Tissue culture plastic; Tissue engineering; Urine; Japan; China; United States > US; Human urine-derived stem cells; Angiogenesis; Tissue culture plastic; Cell adhesion; Cell expansion; Extracellular matrix; Human periodontal ligament stem cells; Fibronectin; Osteogenesis; Adipogenesis

Human periodontal ligament stem cells (hPDLSCs) are one of the most promising types of seed cells in periodontal tissue regeneration. Suitable biomaterials are additional essential components that must cooperate with seed cells for in vivo expansion or in vitro implantation. Extracellular matrix (EC...