A highly curable lymphoma occurs preferentially in the proximal tibia of young patients

• Published in: Modern pathology Vol. 27; no. 11; pp. 1430 - 1437
• Main Authors: Subik, M Kristina, Herr, Megan M, Hutchison, Robert E, Kelly, Jennifer, Tyler, Wakenda K, Merzianu, Mihai, Burack, W Richard
• Format: Journal Article
• Language: English
• Published: New York Elsevier Inc 01.11.2014; Nature Publishing Group US; Elsevier Limited
• Subjects: 692/699/67/1344; 692/699/67/1990/291/1621/1915; 692/700/139/422; Adolescent; Adult; Age; Age Distribution; Age Factors; Aged; Aged, 80 and over; Antigens, CD20 - analysis; Biomarkers, Tumor - analysis; Biopsy; bone lymphoma; Bone Neoplasms - chemistry; Bone Neoplasms - mortality; Bone Neoplasms - pathology; Bone Neoplasms - therapy; Cancer therapies; Child; Child, Preschool; Datasets; Epidemiology; Female; Histology; Humans; Immunohistochemistry; Infant; Infant, Newborn; Kaplan-Meier Estimate; Laboratory Medicine; Lymphoma; Lymphoma - chemistry; Lymphoma - mortality; Lymphoma - pathology; Lymphoma - therapy; Male; Medical prognosis; Medicine; Medicine & Public Health; Middle Aged; Neoplasm Staging; non-Hodgkin lymphoma; original-article; Pathology; Preventive medicine; Radiography; Remission Induction; Risk Factors; SEER Program; Surveillance; tibia; Tibia - chemistry; Tibia - diagnostic imaging; Tibia - pathology; Treatment Outcome; United States - epidemiology; X-rays; Young Adult; United States > US; bone lymphoma; epidemiology; non-Hodgkin lymphoma; tibia

The presentation of two 19-year-old male subjects with stage I non-Hodgkin lymphoma in the proximal tibia prompted an extensive review of institutional and national databases to assess whether there is any statistical evidence that these reflected a previously overlooked syndromic pattern of present...