Surveillance of broad-spectrum antibiotic prescription in Singaporean hospitals: a 5-year longitudinal study

• Published in: PloS one Vol. 6; no. 12; p. e28751
• Main Authors: Liew, Yi-Xin, Krishnan, Prabha, Yeo, Chay-Leng, Tan, Thean-Yen, Lee, Siok-Ying, Lim, Wan-Peng, Lee, Winnie, Hsu, Li-Yang
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 09.12.2011; Public Library of Science (PLoS)
• Subjects: Analysis; Anti-Bacterial Agents - classification; Anti-Bacterial Agents - pharmacology; Antibiotics; Antiinfectives and antibacterials; Antimicrobial agents; Antimicrobial resistance; Carbapenems; Cephalosporins; Correlation analysis; Data processing; Drug dosages; Drug Prescriptions - statistics & numerical data; Drug resistance; Fluoroquinolones; Gram-negative bacteria; Health care costs; Health Care Surveys; Health Expenditures; Hospitals; Hospitals - statistics & numerical data; Humans; Laboratories; Longitudinal Studies; Medicine; Microbial drug resistance; Pharmacy; Piperacillin; Population Surveillance; Public sector; Regression analysis; Singapore - epidemiology; Staphylococcus infections; Surveillance; Tazobactam; Trends; Singapore

Inappropriate prescription of antibiotics may contribute towards higher levels antimicrobial resistance. A key intervention for improving appropriate antibiotic prescription is surveillance of prescription. This paper presents the results of a longitudinal surveillance of broad-spectrum antibiotic p...