Natural history of mild subclinical hypothyroidism in a middle-aged and elderly Chinese population: a prospective study

• Published in: ENDOCRINE JOURNAL Vol. 64; no. 4; pp. 437 - 447
• Main Authors: Li, Xiang, Zhen, Donghu, Zhao, Meng, Liu, Lu, Guan, Qingbo, Zhang, Haiqing, Ge, Shujian, Tang, Xulei, Gao, Ling
• Format: Journal Article
• Language: English; Japanese
• Published: Japan The Japan Endocrine Society 2017; Japan Science and Technology Agency
• Subjects: Adult; Age Factors; Aged; Aged, 80 and over; Aging - ethnology; Aging - physiology; Asian Continental Ancestry Group - statistics & numerical data; Asymptomatic Diseases; China - epidemiology; Cholesterol; Creatinine; Disease Progression; Female; Geriatrics; Health risk assessment; Humans; Hypothyroidism; Hypothyroidism - epidemiology; Hypothyroidism - pathology; Iodide peroxidase; Male; Middle Aged; Natural history; Patients; Peroxidase; Population studies; Prevalence; Prospective study; Risk factors; Severity of Illness Index; Thyroid; Thyroid gland; Thyroid-stimulating hormone; Thyrotropin; Thyrotropin; Hypothyroidism; Prospective study; Natural history; Risk factors

Subclinical hypothyroidism (SCH) has a high global prevalence. Most SCH patients have mild cases (thyrotropin ≤10 mIU/L). Treatment recommendations for mild SCH are controversial, which raises concerns about the natural history of mild SCH. We aimed to clarify the natural history of mild SCH. This i...