Administration of L-type Bovine Spongiform Encephalopathy to Macaques to Evaluate Zoonotic Potential - Imamura, Morikazu; Hagiwara, Ken’ichi; Tobiume, Minoru; Ohno, Minako; Iguchi, Hiromi; Takatsuki, Hanae; Mori, Tsuyoshi; Atarashi, Ryuichiro; Shibata, Hiroaki; Ono, Fumiko (Emerging infectious diseases, 2025)
Keywords: Administration of L-Type Bovine Spongiform Encephalopathy to Macaques to Evaluate Zoonotic Potential; Animals; Asymptomatic; Beef cattle; Bovine spongiform encephalopathy; Brain - metabolism; Brain - pathology; Brain research; Cattle; Creutzfeldt-Jakob disease; cynomolgus macaques; Disease transmission; Dispatch; Encephalopathy, Bovine Spongiform - metabolism; Encephalopathy, Bovine Spongiform - pathology; Encephalopathy, Bovine Spongiform - transmission; Genetic engineering; Health aspects; Humans; Immunohistochemistry; L-Type bovine spongiform encephalopathy; Lymphatic system; Macaca; Macaques; Monkeys & apes; Nervous system; oral transmission; Physiological aspects; Prions; Prions - administration & dosage; Prions - metabolism; Proteins; PrPSc Proteins - administration & dosage; PrPSc Proteins - metabolism; Risk factors; Seeds; Small intestine; Spinal cord; Spleen; Transgenic animals; Zoonoses; Zoonoses - transmission; Japan; Japan; bovine spongiform encephalopathy; cynomolgus macaques; Macaca fascicularis; L-Type bovine spongiform encephalopathy; zoonoses; prions; oral transmission