Impact of the SARS-CoV-2 nucleocapsid 203K/204R mutations on the inflammatory immune response in COVID-19 severity - Shuaib, Muhammad; Adroub, Sabir; Mourier, Tobias; Mfarrej, Sara; Zhang, Huoming; Esau, Luke; Alsomali, Afrah; Alofi, Fadwa S; Ahmad, Adeel Nazir; Shamsan, Abbas; Khogeer, Asim; Hashem, Anwar M.; et al. (Genome Medicine, 2023)
Keywords: Analysis; Biological response modifiers; Cell culture; Chemokines; COVID-19; COVID-19 - immunology; COVID-19 vaccines; Cytokine Storm; Cytokines; Data processing; Disease transmission; Drug development; Genes; Genetic aspects; Genetics; Genomes; Health aspects; HEK293 Cells; Host Immune Response; Humans; Immune response; Immunotherapy; Infection; Inflammation; Inflammation - immunology; Interferon; Interferon-stimulated Genes (Isgs); Leukocytes (neutrophilic); Lymphocytes; Medical research; Medicine; Medicine, Experimental; Mutation; N protein; Nucleocapsid (N) R203K/G204R (KR) mutations; Nucleocapsids; Pandemics; Patients; Proteins; Proteomics; QH426-470; R; SARS-CoV-2; SARS-CoV-2 - genetics; Severe acute respiratory syndrome coronavirus 2; Severity of Illness Index; Transcriptomes; Transcriptomics; Vaccine development; Variant Of Concern; Virus-like particle (VLP); United States--US; COVID-19; Virus-like particle (VLP); Interferon-stimulated genes (ISGs); SARS-CoV-2; Transcriptomics; Proteomics; Nucleocapsid (N) R203K/G204R (KR) mutations; Host immune response; Cytokine storm; Variant of concern