Multiscale modeling of HBV infection integrating intra- and intercellular viral propagation to analyze extracellular viral markers - Kitagawa, Kosaku; Kim, Kwang Su; Iwamoto, Masashi; Hayashi, Sanae; Park, Hyeongki; Nishiyama, Takara; Nakamura, Naotoshi; Fujita, Yasuhisa; Nakaoka, Shinji; Aihara, Kazuyuki; Perelson, Alan S.; Allweiss, Lena; et al. (PLoS computational biology, 2024)
Keywords: Analysis; Antigens; Antiviral Agents - therapeutic use; B cells; BASIC BIOLOGICAL SCIENCES; Biological Science; Biology and Life Sciences; Biomarkers; Biopsy; Cell culture; Chronic infection; Circular DNA; Datasets; Deoxyribonucleic acid; Differential equations; DNA; DNA, Circular; DNA, Viral - genetics; Experiments; Health aspects; Hepatitis; Hepatitis B; Hepatitis B - drug therapy; Hepatitis B - pathology; Hepatitis B e antigen; Hepatitis B e Antigens - genetics; Hepatitis B surface antigen; Hepatitis B Surface Antigens - genetics; Hepatitis B virus; Hepatitis B virus - genetics; Hepatocytes; Humans; In vivo methods and tests; Infection; Infections; Liver; Liver - pathology; Mathematical models; Medicine and Health Sciences; Ordinary differential equations; Partial differential equations; Peripheral blood; Pharmacology; Proteins; Research and Analysis Methods; Viral infections; Japan