Evidence of Lineage 1 and 3 West Nile Virus in Person with Neuroinvasive Disease, Nebraska, USA, 2023

• Published in: Emerging infectious diseases Vol. 30; no. 10; pp. 2090 - 2098
• Main Authors: Davis, Emily, Velez, Jason, Hamik, Jeff, Fitzpatrick, Kelly, Haley, Jacki, Eschliman, Jeremy, Panella, Amanda, Staples, J. Erin, Lambert, Amy, Donahue, Matthew, Brault, Aaron C., Hughes, Holly R.
• Format: Journal Article
• Language: English
• Published: United States U.S. National Center for Infectious Diseases 01.10.2024; Centers for Disease Control and Prevention
• Subjects: Asymptomatic; Cardiovascular disease; Case studies; Central nervous system diseases; co-infection; Disease transmission; Evidence of Lineage 1 and 3 West Nile Virus in Person with Neuroinvasive Disease, Nebraska, USA, 2023; Genetic aspects; Genome, Viral; Genomics; Health aspects; Hospitals; Humans; Infections; lineage 3; Medical laboratories; Medical research; Medicine, Experimental; Nebraska - epidemiology; Ostomy; Phylogeny; Physiological aspects; Proteins; Public health; Rabensburg virus; Risk factors; Type 2 diabetes; Vector-borne diseases; Viruses; West Nile fever; West Nile Fever - epidemiology; West Nile Fever - virology; West Nile virus; West Nile virus - genetics; zoonoses; Nebraska; United States; Colorado; United States > US; Europe; Africa; Rabensburg virus; viruses; vector-borne infections; co-infection; United States; West Nile virus; lineage 3; West Nile neuroinvasive disease; zoonoses; genomic surveillance

West Nile virus (WNV) is the most common cause of human arboviral disease in the contiguous United States, where only lineage 1 (L1) WNV had been found. In 2023, an immunocompetent patient was hospitalized in Nebraska with West Nile neuroinvasive disease and multisystem organ failure. Testing at the...