Subjective cognitive decline: Self and informant comparisons

• Published in: Alzheimer's & dementia Vol. 10; no. 1; pp. 93 - 98
• Main Authors: Caselli, Richard J, Chen, Kewei, Locke, Dona E.C, Lee, Wendy, Roontiva, Auttawut, Bandy, Dan, Fleisher, Adam S, Reiman, Eric M
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.01.2014; ALZHEIMER'S & DEMENTIA
• Subjects: Acoustic Stimulation; Aged; Alzheimer's disease; Apolipoproteins E - genetics; Cognition Disorders - diagnosis; Cognition Disorders - psychology; Cognitive aging; Cognitive impairment; Cognitive performance; Cohort Studies; Executive Function; Female; Humans; Informants; Language Disorders - etiology; Male; Middle Aged; Mild cognitive impairment; Neurologic Examination; Neurology; Neuropsychological Tests; Preclinical Alzheimer's disease; Psychological distress; Psychomotor Performance; Self; Self Report; Severity of Illness Index; Space Perception - physiology; Subjective cognition; Surveys and Questionnaires; Verbal Learning; Cognitive aging; Subjective cognition; Mild cognitive impairment; Preclinical Alzheimer's disease

Abstract Background It is unclear whether self- or informant-based subjective cognition better distinguishes emotional factors from early-stage Alzheimer's disease (AD). Methods Healthy members (n = 447) of the Arizona apolipoprotein E ( APOE ) cohort and their informants completed the self and...