Neutralizing Enterovirus D68 Antibodies in Children after 2014 Outbreak, Kansas City, Missouri, USA

• Published in: Emerging infectious diseases Vol. 28; no. 3; pp. 539 - 547
• Main Authors: Livingston, Robyn A., Harrison, Christopher J., Selvarangan, Rangaraj
• Format: Journal Article
• Language: English
• Published: United States U.S. National Center for Infectious Diseases 01.03.2022; Centers for Disease Control and Prevention
• Subjects: Age groups; Antibodies; Antibodies, Neutralizing; Asthma; Child; children; Demographic aspects; Disease control; Disease Outbreaks; Distribution; enterovirus; Enterovirus D, Human - genetics; Enterovirus Infections - epidemiology; Enteroviruses; Epidemics; Ethnicity; EV-D68; Health surveillance; Hispanic Americans; Humans; Identification and classification; Infant; Kansas; Medical records; Missouri - epidemiology; Multivariate analysis; neutralizing antibody; Outbreaks; Pediatric research; Respiratory Tract Infections - epidemiology; seroprevalence; Variance analysis; Viral antibodies; Viruses; Missouri; Kansas; United States; United States > US; Kansas City Missouri; Kansas City; USA; viruses; enterovirus; EV-D68; seroprevalence; neutralizing antibody; asthma; B2 clade; D clade; children; B1 clade; Missouri

Enterovirus D68 (EV-D68) causes severe respiratory illness outbreaks among children, particularly those with asthma. We previously detected neutralizing antibodies against the predominant EV-D68 B1 clade in the 2014 outbreak in serum collected before the outbreak (2012–2013) from persons 24 months t...