Histopathological Characterization of Cases of Spontaneous Fatal Feline Severe Fever with Thrombocytopenia Syndrome, Japan

• Published in: Emerging infectious diseases Vol. 27; no. 4; pp. 1068 - 1076
• Main Authors: Sakai, Yusuke, Kuwabara, Yuko, Ishijima, Keita, Kagimoto, Saya, Mura, Serina, Tatemoto, Kango, Kuwata, Ryusei, Yonemitsu, Kenzo, Minami, Shohei, Kuroda, Yudai, Baba, Kenji, Okuda, Masaru, Shimoda, Hiroshi, Sakurai, Masashi, Morimoto, Masahiro, Maeda, Ken
• Format: Journal Article
• Language: English
• Published: United States U.S. National Center for Infectious Diseases 01.04.2021; Centers for Disease Control and Prevention
• Subjects: Animals; Antibodies; Antigens; Case reports; Cats; Cloning; Cytokeratin; Development and progression; Disease transmission; Diseases; Fever; Gastrointestinal tract; Hemorrhage; Histopathological Characterization of Cases of Spontaneous Fatal Feline Severe Fever with Thrombocytopenia Syndrome, Japan; histopathology; Infections; Infectious diseases; Lesions; Lymphatic system; Lymphocytes; Mammals; Morphology; Prevention; Severe fever with thrombocytopenia syndrome virus; SFTS; SFTSV; Spleen; Thrombocytopenia; Thymus gland; Ulcers; zoonoses; Japan; Severe fever with thrombocytopenia syndrome virus; viruses; cats; vector-borne infections; SFTS; Japan; SFTSV; felines; histopathology; tickborne diseases; zoonoses

Severe fever with thrombocytopenia syndrome (SFTS) is an emerging tickborne infectious disease caused by SFTS virus (SFTSV). We report 7 cases of spontaneous fatal SFTS in felines. Necropsies revealed characteristic lesions, including necrotizing lymphadenitis in 5 cases and necrotizing splenitis an...