A single, improbable B cell receptor mutation confers potent neutralization against cytomegalovirus - Jenks, Jennifer A.; Amin, Sharmi; Sponholtz, Madeline R.; Kumar, Amit; Wrapp, Daniel; Venkatayogi, Sravani; Tu, Joshua J.; Karthigeyan, Krithika; Valencia, Sarah M.; Connors, Megan; Harnois, Melissa J.; Hora, Bhavna; et al. (PLoS pathogens, 2023)
Keywords: Amino acids; Antibodies; Antibodies, Neutralizing - genetics; Antibodies, Neutralizing - immunology; Antibodies, Viral - genetics; Antibodies, Viral - immunology; Antigens; BASIC BIOLOGICAL SCIENCES; Biology and Life Sciences; Care and treatment; Cell receptors; Cloning; Congenital diseases; Cytomegalovirus; Cytomegalovirus - genetics; Cytomegalovirus - immunology; Cytomegalovirus infections; Cytomegalovirus Infections - genetics; Cytomegalovirus Infections - immunology; Cytomegalovirus Vaccines - therapeutic use; Development and progression; Epitopes; Gene mutations; Genealogy; Genetic aspects; Glycoprotein B; Glycoproteins; Health aspects; Hearing loss; Host-virus relationships; Humans; Immune response; Infections; Lymphocytes B; Medicine and Health Sciences; Microbiology; Mutation; Neutralization; Neutralizing; Parasitology; Phylogenetics; Receptors, Antigen, B-Cell - genetics; Receptors, Antigen, B-Cell - immunology; Somatic hypermutation; Vaccines; Viral Envelope Proteins - genetics; Viral Envelope Proteins - immunology; Virology; United States