Synthesis and Phytotoxic Activities of N-Substituted Phenyl Isothiazolone Derivatives

• Published in: Journal of Pesticide Science Vol. 28; no. 3; pp. 293 - 300
• Main Authors: MIYAMOTO, Yoshiko, IKEDA, Yumi, WAKABAYASHI, Ko
• Format: Journal Article
• Language: English; Japanese
• Published: Tokyo Pesticide Science Society of Japan 01.01.2003; Japan Science and Technology Agency
• Subjects: 3(2H)-oxo-N-(substituted phenyl)-4,5,6,7-tetrahydro-1,2-benzisothiazoles; 3-oxo-4,5,6,7-tetrahydro-1,2-benzisothiazole-1,1-dioxides; 3-oxo-4,5,6,7-tetrahydro-1,2-benzisothiazole-1-oxides; Biological and medical sciences; Fundamental and applied biological sciences. Psychology; peroxidizing activity; Phytopathology. Animal pests. Plant and forest protection; protoporphyrinogen-IX oxidase; Scenedesmus acutus; Zea mays; 3-oxo-4,5,6,7-tetrahydro-1,2-benzisothiazole-1,1-dioxides; peroxidizing activity; Enzyme; 3-oxo-4,5,6,7-tetrahydro-1,2-benzisothiazole-1-oxides; Oxidase; Pesticides; protoporphyrinogen-IX oxidase; Oxidoreductases; 3(2H)-oxo-N-(substituted phenyl)-4,5,6,7-tetrathydro-1,2-benzisothiazoles

A series of 3(2H)-oxo-N-(substituted phenyl)-4,5,6,7-tetrahydro-1,2-benzisothiazoles (2) were obtained via four reaction steps starting from 2-chlorocyclohexene-1-carboxylic acid. The sulfur atom of 3-oxo-4,5,6,7-tetrahydro-1,2-benzisothiazoles (2) was oxidized with an equimolecular amount of 3-chlo...